Matches in SemOpenAlex for { <https://semopenalex.org/work/W2964672079> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2964672079 endingPage "943" @default.
- W2964672079 startingPage "935" @default.
- W2964672079 abstract "Background: Recent improvements in optimal cardiovascular therapy have questioned the beneficial effects of polyunsaturated fatty acids (PUFAs) observed in previous studies. Aims: We investigated the fatty acid (FA) composition in serum phospholipids in patients with an established acute phase of myocardial infarction (MI) and in high‑risk patients with stable atherosclerotic cardiovascular disease (CVD). Methods: We studied 83 patients hospitalized within 12 hours from the onset of the first clinical symptoms of MI. As a control group, we assessed 74 patients at high cardiovascular risk with an established stable atherosclerotic CVD treated at an outpatient cardiology clinic. Gas chromatography was used to evaluate the FA composition in serum phospholipids in both groups. Results: The final analysis included 52 patients with acute MI and 74 controls. In both groups, saturated FAs constituted the largest fraction of serum phospholipid FAs (median, 1574.67 μmol/l), followed by n‑6 PUFAs (median, 1106.99 μmol/l). The levels of total saturated FAs, monounsaturated FAs, n‑6 PUFAs, as well as the ratio of n‑6 to n‑3 PUFAs significantly differed between groups. Palmitic acid constituted the largest fraction of serum phospholipids both in patients and controls (31.9% and 31.16%, respectively). In a multivariate logistic regression analysis, body mass index, low‑density lipoprotein cholesterol, aspartate aminotransferase, high‑sensitivity C‑reactive protein, and palmitoleic and eicosadienoic acids were independently associated with MI. Conclusions: We showed major differences in the FA composition of serum phospholipids between patients with acute MI and high‑risk individuals with stable atherosclerotic CVD. Eicosadienoic and palmitoleic acids, apart from typical cardiovascular risk factors, were independently associated with MI." @default.
- W2964672079 created "2019-08-13" @default.
- W2964672079 creator A5001190600 @default.
- W2964672079 creator A5016462644 @default.
- W2964672079 creator A5020822991 @default.
- W2964672079 creator A5024093697 @default.
- W2964672079 creator A5025085756 @default.
- W2964672079 creator A5030149598 @default.
- W2964672079 creator A5060775652 @default.
- W2964672079 creator A5061454014 @default.
- W2964672079 creator A5062831144 @default.
- W2964672079 creator A5069033622 @default.
- W2964672079 date "2019-10-25" @default.
- W2964672079 modified "2023-09-30" @default.
- W2964672079 title "Unsaturated fatty acid composition in serum phospholipids in patients in the acute phase of myocardial infarction" @default.
- W2964672079 doi "https://doi.org/10.33963/kp.14923" @default.
- W2964672079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31387982" @default.
- W2964672079 hasPublicationYear "2019" @default.
- W2964672079 type Work @default.
- W2964672079 sameAs 2964672079 @default.
- W2964672079 citedByCount "5" @default.
- W2964672079 countsByYear W29646720792020 @default.
- W2964672079 countsByYear W29646720792021 @default.
- W2964672079 countsByYear W29646720792022 @default.
- W2964672079 crossrefType "journal-article" @default.
- W2964672079 hasAuthorship W2964672079A5001190600 @default.
- W2964672079 hasAuthorship W2964672079A5016462644 @default.
- W2964672079 hasAuthorship W2964672079A5020822991 @default.
- W2964672079 hasAuthorship W2964672079A5024093697 @default.
- W2964672079 hasAuthorship W2964672079A5025085756 @default.
- W2964672079 hasAuthorship W2964672079A5030149598 @default.
- W2964672079 hasAuthorship W2964672079A5060775652 @default.
- W2964672079 hasAuthorship W2964672079A5061454014 @default.
- W2964672079 hasAuthorship W2964672079A5062831144 @default.
- W2964672079 hasAuthorship W2964672079A5069033622 @default.
- W2964672079 hasBestOaLocation W29646720791 @default.
- W2964672079 hasConcept C126322002 @default.
- W2964672079 hasConcept C134018914 @default.
- W2964672079 hasConcept C185592680 @default.
- W2964672079 hasConcept C19038510 @default.
- W2964672079 hasConcept C2778163477 @default.
- W2964672079 hasConcept C2778918659 @default.
- W2964672079 hasConcept C2779641957 @default.
- W2964672079 hasConcept C2779936771 @default.
- W2964672079 hasConcept C2780221984 @default.
- W2964672079 hasConcept C41625074 @default.
- W2964672079 hasConcept C500558357 @default.
- W2964672079 hasConcept C543025807 @default.
- W2964672079 hasConcept C55493867 @default.
- W2964672079 hasConcept C71924100 @default.
- W2964672079 hasConcept C90924648 @default.
- W2964672079 hasConceptScore W2964672079C126322002 @default.
- W2964672079 hasConceptScore W2964672079C134018914 @default.
- W2964672079 hasConceptScore W2964672079C185592680 @default.
- W2964672079 hasConceptScore W2964672079C19038510 @default.
- W2964672079 hasConceptScore W2964672079C2778163477 @default.
- W2964672079 hasConceptScore W2964672079C2778918659 @default.
- W2964672079 hasConceptScore W2964672079C2779641957 @default.
- W2964672079 hasConceptScore W2964672079C2779936771 @default.
- W2964672079 hasConceptScore W2964672079C2780221984 @default.
- W2964672079 hasConceptScore W2964672079C41625074 @default.
- W2964672079 hasConceptScore W2964672079C500558357 @default.
- W2964672079 hasConceptScore W2964672079C543025807 @default.
- W2964672079 hasConceptScore W2964672079C55493867 @default.
- W2964672079 hasConceptScore W2964672079C71924100 @default.
- W2964672079 hasConceptScore W2964672079C90924648 @default.
- W2964672079 hasIssue "10" @default.
- W2964672079 hasLocation W29646720791 @default.
- W2964672079 hasLocation W29646720792 @default.
- W2964672079 hasLocation W29646720793 @default.
- W2964672079 hasOpenAccess W2964672079 @default.
- W2964672079 hasPrimaryLocation W29646720791 @default.
- W2964672079 hasRelatedWork W1968557336 @default.
- W2964672079 hasRelatedWork W2119874811 @default.
- W2964672079 hasRelatedWork W2222972601 @default.
- W2964672079 hasRelatedWork W2504578072 @default.
- W2964672079 hasRelatedWork W2765787588 @default.
- W2964672079 hasRelatedWork W2806054105 @default.
- W2964672079 hasRelatedWork W3125677434 @default.
- W2964672079 hasRelatedWork W4252215692 @default.
- W2964672079 hasRelatedWork W57542679 @default.
- W2964672079 hasRelatedWork W966258111 @default.
- W2964672079 hasVolume "77" @default.
- W2964672079 isParatext "false" @default.
- W2964672079 isRetracted "false" @default.
- W2964672079 magId "2964672079" @default.
- W2964672079 workType "article" @default.