FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2964674038> ?p ?o ?g. }

• W2964674038 endingPage "97" @default.
• W2964674038 startingPage "91" @default.
• W2964674038 abstract "Acetylcholinesterase (AChE), an efficient biocatalyst known to hydrolyze the neurotransmitter acetylcholine, could be inactivated in the presence of insecticides, nerve agents or other drug inhibitors to thus result in disrupted neurotransmission. Improvement in the peripheral cholinergic function, as well as overall cognition and neuronal functions of an exposed system could be achieved if the mechanisms of inhibitions are deactivated in a controlled fashion and with rapid response time. Herein, we proposed to develop a simple AChE biosensor capable to realize the rapid detection of neurotoxins. Our approach uses a nanoporous gold film (NPGF) and reduced graphene oxide-tin dioxide nanoparticle (RGO-SnO2) nanocomposite to define the highly active electrode interface where the electrochemical monitoring of the interaction between AChE and its target molecule, fasciculin, could take place. Our results demonstrate that the established biosensor had the ability to monitor fasciculin concentrations at the ultra-low limit of detection of 8 pM, an inhibition rate of 8% and within only 30min of electrochemical exposure. Our study provides a convenient technology for the rapid and ultrasensitive detection of neurotoxins and has the potential for large applicability to other drugs or toxins screening." @default.
• W2964674038 created "2019-08-13" @default.
• W2964674038 creator A5031109115 @default.
• W2964674038 creator A5035799232 @default.
• W2964674038 date "2019-11-01" @default.
• W2964674038 modified "2023-09-26" @default.
• W2964674038 title "Nanoporous gold electrode for ultrasensitive detection of neurotoxin fasciculin" @default.
• W2964674038 cites W1536459857 @default.
• W2964674038 cites W1964532701 @default.
• W2964674038 cites W1976840708 @default.
• W2964674038 cites W1993588466 @default.
• W2964674038 cites W1997585234 @default.
• W2964674038 cites W2004964314 @default.
• W2964674038 cites W2005975895 @default.
• W2964674038 cites W2015399821 @default.
• W2964674038 cites W2022326355 @default.
• W2964674038 cites W2024214628 @default.
• W2964674038 cites W2034028211 @default.
• W2964674038 cites W2039443450 @default.
• W2964674038 cites W2040201607 @default.
• W2964674038 cites W2047890697 @default.
• W2964674038 cites W2056901753 @default.
• W2964674038 cites W2058994454 @default.
• W2964674038 cites W2059718082 @default.
• W2964674038 cites W2068885078 @default.
• W2964674038 cites W2071437690 @default.
• W2964674038 cites W2074538331 @default.
• W2964674038 cites W2079248608 @default.
• W2964674038 cites W2080548892 @default.
• W2964674038 cites W2085907924 @default.
• W2964674038 cites W2113337802 @default.
• W2964674038 cites W2141957506 @default.
• W2964674038 cites W2151233652 @default.
• W2964674038 cites W2160580407 @default.
• W2964674038 cites W2176951640 @default.
• W2964674038 cites W2313045075 @default.
• W2964674038 cites W2319038105 @default.
• W2964674038 cites W2510032947 @default.
• W2964674038 cites W2619530431 @default.
• W2964674038 cites W2791369602 @default.
• W2964674038 cites W4211157318 @default.
• W2964674038 doi "https://doi.org/10.1016/j.aca.2019.07.067" @default.
• W2964674038 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31522735" @default.
• W2964674038 hasPublicationYear "2019" @default.
• W2964674038 type Work @default.
• W2964674038 sameAs 2964674038 @default.
• W2964674038 citedByCount "3" @default.
• W2964674038 countsByYear W29646740382021 @default.
• W2964674038 countsByYear W29646740382022 @default.
• W2964674038 crossrefType "journal-article" @default.
• W2964674038 hasAuthorship W2964674038A5031109115 @default.
• W2964674038 hasAuthorship W2964674038A5035799232 @default.
• W2964674038 hasBestOaLocation W29646740381 @default.
• W2964674038 hasConcept C104819515 @default.
• W2964674038 hasConcept C119128265 @default.
• W2964674038 hasConcept C155672457 @default.
• W2964674038 hasConcept C160756335 @default.
• W2964674038 hasConcept C171250308 @default.
• W2964674038 hasConcept C181199279 @default.
• W2964674038 hasConcept C185592680 @default.
• W2964674038 hasConcept C192562407 @default.
• W2964674038 hasConcept C21951064 @default.
• W2964674038 hasConcept C2775910092 @default.
• W2964674038 hasConcept C2778816929 @default.
• W2964674038 hasConcept C2780358027 @default.
• W2964674038 hasConcept C43617362 @default.
• W2964674038 hasConcept C55493867 @default.
• W2964674038 hasConcept C71924100 @default.
• W2964674038 hasConcept C98274493 @default.
• W2964674038 hasConceptScore W2964674038C104819515 @default.
• W2964674038 hasConceptScore W2964674038C119128265 @default.
• W2964674038 hasConceptScore W2964674038C155672457 @default.
• W2964674038 hasConceptScore W2964674038C160756335 @default.
• W2964674038 hasConceptScore W2964674038C171250308 @default.
• W2964674038 hasConceptScore W2964674038C181199279 @default.
• W2964674038 hasConceptScore W2964674038C185592680 @default.
• W2964674038 hasConceptScore W2964674038C192562407 @default.
• W2964674038 hasConceptScore W2964674038C21951064 @default.
• W2964674038 hasConceptScore W2964674038C2775910092 @default.
• W2964674038 hasConceptScore W2964674038C2778816929 @default.
• W2964674038 hasConceptScore W2964674038C2780358027 @default.
• W2964674038 hasConceptScore W2964674038C43617362 @default.
• W2964674038 hasConceptScore W2964674038C55493867 @default.
• W2964674038 hasConceptScore W2964674038C71924100 @default.
• W2964674038 hasConceptScore W2964674038C98274493 @default.
• W2964674038 hasFunder F4320306076 @default.
• W2964674038 hasLocation W29646740381 @default.
• W2964674038 hasLocation W29646740382 @default.
• W2964674038 hasOpenAccess W2964674038 @default.
• W2964674038 hasPrimaryLocation W29646740381 @default.
• W2964674038 hasRelatedWork W1476210231 @default.
• W2964674038 hasRelatedWork W2020992299 @default.
• W2964674038 hasRelatedWork W2079420693 @default.
• W2964674038 hasRelatedWork W2080974378 @default.
• W2964674038 hasRelatedWork W2117085255 @default.
• W2964674038 hasRelatedWork W2379337788 @default.
• W2964674038 hasRelatedWork W2466955330 @default.
• W2964674038 hasRelatedWork W3215014983 @default.

• next