Matches in SemOpenAlex for { <https://semopenalex.org/work/W2964871706> ?p ?o ?g. }
- W2964871706 endingPage "86" @default.
- W2964871706 startingPage "86" @default.
- W2964871706 abstract "Women with polycystic ovary syndrome (PCOS) exhibit compromised psychiatric health. Independent of obesity, women with PCOS are more susceptible to have anxiety and depression diagnoses and other neuropsychiatric disorders. During pregnancy women with PCOS display high circulating androgen levels that may cause prenatal androgen exposure affecting the growing fetus and increasing the risk of mood disorders in offspring. Increasing evidence supports a non-genetic, maternal contribution to the development of PCOS and anxiety disorders in the next generation. Prenatal androgenized rodent models reflecting the anxiety-like phenotype of PCOS in the offspring, found evidence for the altered placenta and androgen receptor function in the amygdala, together with changes in the expression of genes associated with emotional regulation and steroid receptors in the amygdala and hippocampus. These findings defined a previously unknown mechanism that may be critical in understanding how maternal androgen excess can increase the risk of developing anxiety disorders in daughters and partly in sons of PCOS mothers. Maternal obesity is another common feature of PCOS causing an unfavorable intrauterine environment which may contribute to psychiatric problems in the offspring. Whether environmental factors such as prenatal androgen exposure and obesity increase the offspring's susceptibility to develop psychiatric ill-health will be discussed." @default.
- W2964871706 created "2019-08-13" @default.
- W2964871706 creator A5017588197 @default.
- W2964871706 creator A5018694155 @default.
- W2964871706 creator A5020474991 @default.
- W2964871706 creator A5034344913 @default.
- W2964871706 creator A5044153066 @default.
- W2964871706 creator A5080231897 @default.
- W2964871706 date "2019-08-05" @default.
- W2964871706 modified "2023-10-13" @default.
- W2964871706 title "Origins and Impact of Psychological Traits in Polycystic Ovary Syndrome" @default.
- W2964871706 cites W1509494994 @default.
- W2964871706 cites W1648886063 @default.
- W2964871706 cites W1651317852 @default.
- W2964871706 cites W1892484122 @default.
- W2964871706 cites W1965007428 @default.
- W2964871706 cites W1966552488 @default.
- W2964871706 cites W1972008706 @default.
- W2964871706 cites W1995855934 @default.
- W2964871706 cites W2037394967 @default.
- W2964871706 cites W2045245727 @default.
- W2964871706 cites W2052785258 @default.
- W2964871706 cites W2056553615 @default.
- W2964871706 cites W2072345165 @default.
- W2964871706 cites W2090160399 @default.
- W2964871706 cites W2092058779 @default.
- W2964871706 cites W2097109759 @default.
- W2964871706 cites W2113329249 @default.
- W2964871706 cites W2124047224 @default.
- W2964871706 cites W2135705669 @default.
- W2964871706 cites W2152809034 @default.
- W2964871706 cites W2157240276 @default.
- W2964871706 cites W2162300184 @default.
- W2964871706 cites W2163267780 @default.
- W2964871706 cites W2166089648 @default.
- W2964871706 cites W2171001171 @default.
- W2964871706 cites W2181053434 @default.
- W2964871706 cites W2193080956 @default.
- W2964871706 cites W2228917354 @default.
- W2964871706 cites W2328563242 @default.
- W2964871706 cites W2337530519 @default.
- W2964871706 cites W2346799376 @default.
- W2964871706 cites W2444481702 @default.
- W2964871706 cites W2488412037 @default.
- W2964871706 cites W2510719007 @default.
- W2964871706 cites W2529680825 @default.
- W2964871706 cites W2558495858 @default.
- W2964871706 cites W2564413725 @default.
- W2964871706 cites W2565294145 @default.
- W2964871706 cites W2592269563 @default.
- W2964871706 cites W2599497774 @default.
- W2964871706 cites W2616520918 @default.
- W2964871706 cites W2745250401 @default.
- W2964871706 cites W2751923968 @default.
- W2964871706 cites W2754934464 @default.
- W2964871706 cites W2755788843 @default.
- W2964871706 cites W2772098745 @default.
- W2964871706 cites W2784049362 @default.
- W2964871706 cites W2784200480 @default.
- W2964871706 cites W2789387689 @default.
- W2964871706 cites W2791934655 @default.
- W2964871706 cites W2795286808 @default.
- W2964871706 cites W2804217905 @default.
- W2964871706 cites W2807678485 @default.
- W2964871706 cites W2808547776 @default.
- W2964871706 cites W2809846828 @default.
- W2964871706 cites W2883713519 @default.
- W2964871706 cites W2884536266 @default.
- W2964871706 cites W2885250903 @default.
- W2964871706 cites W2886652575 @default.
- W2964871706 cites W2901919511 @default.
- W2964871706 cites W2907939901 @default.
- W2964871706 cites W2913432589 @default.
- W2964871706 cites W2914893853 @default.
- W2964871706 cites W2922186175 @default.
- W2964871706 cites W2935716359 @default.
- W2964871706 cites W2936954914 @default.
- W2964871706 cites W2944563270 @default.
- W2964871706 cites W4212784858 @default.
- W2964871706 doi "https://doi.org/10.3390/medsci7080086" @default.
- W2964871706 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6723772" @default.
- W2964871706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31387252" @default.
- W2964871706 hasPublicationYear "2019" @default.
- W2964871706 type Work @default.
- W2964871706 sameAs 2964871706 @default.
- W2964871706 citedByCount "8" @default.
- W2964871706 countsByYear W29648717062019 @default.
- W2964871706 countsByYear W29648717062020 @default.
- W2964871706 countsByYear W29648717062021 @default.
- W2964871706 countsByYear W29648717062022 @default.
- W2964871706 crossrefType "journal-article" @default.
- W2964871706 hasAuthorship W2964871706A5017588197 @default.
- W2964871706 hasAuthorship W2964871706A5018694155 @default.
- W2964871706 hasAuthorship W2964871706A5020474991 @default.
- W2964871706 hasAuthorship W2964871706A5034344913 @default.
- W2964871706 hasAuthorship W2964871706A5044153066 @default.
- W2964871706 hasAuthorship W2964871706A5080231897 @default.
- W2964871706 hasBestOaLocation W29648717061 @default.