FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2965334713> ?p ?o ?g. }

• W2965334713 abstract "Abstract The complexities of the human musculoskeletal system and its interactions with the environment creates a difficult challenge for the neural control of movement. The consensus is that the nervous system solves this challenge by embedding the dynamical properties of the body and the environment. However, the modality of control signals and how they are generated appropriately for the task demands are a matter of active debate. We used transcranial magnetic stimulation over the primary motor cortex to show that the excitability of the corticospinal tract is modulated to compensate for limb dynamics during reaching tasks in humans. Surprisingly, few profiles of corticospinal modulation in some muscles and conditions reflected Newtonian parameters of movement, such as kinematics or active torques. Instead, the overall corticospinal excitability was differentially modulated in proximal and distal muscles, which corresponded to different stiffness at proximal and distal joints. This suggests that the descending corticospinal signal determines the proximal and distal impedance of the arm for independent functional control of reaching and grasping. Significance Statement The nervous system integrates both the physical properties of the human body and the environment to create a rich repertoire of actions. How these calculations are happening remains poorly understood. Neural activity is known to be correlated with different variables from the Newtonian equations of motion that describe forces acting on the body. In contrast, our data show that the overall activity of the descending neural signals is less related to the individual Newtonian variables and more related to limb impedance. We show that the physical properties of the arm are controlled by two distinct proximal and distal descending neural signals modulating components of limb stiffness. This identifies distinct neural control mechanisms for the transport and manipulation actions of reach." @default.
• W2965334713 created "2019-08-13" @default.
• W2965334713 creator A5038487365 @default.
• W2965334713 creator A5064774535 @default.
• W2965334713 creator A5078340570 @default.
• W2965334713 date "2019-08-02" @default.
• W2965334713 modified "2023-10-17" @default.
• W2965334713 title "Distinct Proximal and Distal Corticospinal Signals Embed Limb Dynamics Through the Modulation of Stiffness" @default.
• W2965334713 cites W1237300015 @default.
• W2965334713 cites W1507199205 @default.
• W2965334713 cites W1552041080 @default.
• W2965334713 cites W1565140245 @default.
• W2965334713 cites W1799331832 @default.
• W2965334713 cites W1809394698 @default.
• W2965334713 cites W1885639605 @default.
• W2965334713 cites W1892385946 @default.
• W2965334713 cites W1922715780 @default.
• W2965334713 cites W1956636948 @default.
• W2965334713 cites W1957096125 @default.
• W2965334713 cites W1965098788 @default.
• W2965334713 cites W1971476140 @default.
• W2965334713 cites W1974803102 @default.
• W2965334713 cites W1976410593 @default.
• W2965334713 cites W1976463849 @default.
• W2965334713 cites W1977042228 @default.
• W2965334713 cites W1980440818 @default.
• W2965334713 cites W1984177076 @default.
• W2965334713 cites W1987011372 @default.
• W2965334713 cites W1991512494 @default.
• W2965334713 cites W2018259456 @default.
• W2965334713 cites W2025036434 @default.
• W2965334713 cites W2027795063 @default.
• W2965334713 cites W2032527661 @default.
• W2965334713 cites W2034753893 @default.
• W2965334713 cites W2037082312 @default.
• W2965334713 cites W2040531906 @default.
• W2965334713 cites W2040739363 @default.
• W2965334713 cites W2041049393 @default.
• W2965334713 cites W2041408427 @default.
• W2965334713 cites W2043289509 @default.
• W2965334713 cites W2049855535 @default.
• W2965334713 cites W2056505888 @default.
• W2965334713 cites W2057566546 @default.
• W2965334713 cites W2059968919 @default.
• W2965334713 cites W2072554570 @default.
• W2965334713 cites W2075199075 @default.
• W2965334713 cites W2078344101 @default.
• W2965334713 cites W2080487795 @default.
• W2965334713 cites W2083770481 @default.
• W2965334713 cites W2083831782 @default.
• W2965334713 cites W2089275835 @default.
• W2965334713 cites W2095037267 @default.
• W2965334713 cites W2142265225 @default.
• W2965334713 cites W2153754775 @default.
• W2965334713 cites W2189979991 @default.
• W2965334713 cites W2492979475 @default.
• W2965334713 cites W2531651136 @default.
• W2965334713 cites W2580741296 @default.
• W2965334713 cites W2621961142 @default.
• W2965334713 cites W2769078659 @default.
• W2965334713 cites W2781324873 @default.
• W2965334713 cites W4211003818 @default.
• W2965334713 cites W998690604 @default.
• W2965334713 doi "https://doi.org/10.1101/723056" @default.
• W2965334713 hasPublicationYear "2019" @default.
• W2965334713 type Work @default.
• W2965334713 sameAs 2965334713 @default.
• W2965334713 citedByCount "0" @default.
• W2965334713 crossrefType "posted-content" @default.
• W2965334713 hasAuthorship W2965334713A5038487365 @default.
• W2965334713 hasAuthorship W2965334713A5064774535 @default.
• W2965334713 hasAuthorship W2965334713A5078340570 @default.
• W2965334713 hasBestOaLocation W29653347131 @default.
• W2965334713 hasConcept C121332964 @default.
• W2965334713 hasConcept C126838900 @default.
• W2965334713 hasConcept C137813230 @default.
• W2965334713 hasConcept C143409427 @default.
• W2965334713 hasConcept C149550507 @default.
• W2965334713 hasConcept C15744967 @default.
• W2965334713 hasConcept C169760540 @default.
• W2965334713 hasConcept C24998067 @default.
• W2965334713 hasConcept C2778581513 @default.
• W2965334713 hasConcept C2779779279 @default.
• W2965334713 hasConcept C2780307956 @default.
• W2965334713 hasConcept C39920418 @default.
• W2965334713 hasConcept C41008148 @default.
• W2965334713 hasConcept C71924100 @default.
• W2965334713 hasConcept C74650414 @default.
• W2965334713 hasConcept C99508421 @default.
• W2965334713 hasConceptScore W2965334713C121332964 @default.
• W2965334713 hasConceptScore W2965334713C126838900 @default.
• W2965334713 hasConceptScore W2965334713C137813230 @default.
• W2965334713 hasConceptScore W2965334713C143409427 @default.
• W2965334713 hasConceptScore W2965334713C149550507 @default.
• W2965334713 hasConceptScore W2965334713C15744967 @default.
• W2965334713 hasConceptScore W2965334713C169760540 @default.
• W2965334713 hasConceptScore W2965334713C24998067 @default.
• W2965334713 hasConceptScore W2965334713C2778581513 @default.
• W2965334713 hasConceptScore W2965334713C2779779279 @default.
• W2965334713 hasConceptScore W2965334713C2780307956 @default.

• next