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- W2965349360 abstract "Breast cancer is the predominant form of cancer among females, with one in eight women likely to develop this disease in their lifetime. The protein INPP4B is a tumour suppressor that is lost in a subset of breast cancers, leading to increased tumour growth. However, the findings in this thesis show that INPP4B levels are increased in a different subset of breast cancers with poorer prognosis. Paradoxically, INPP4B overexpression was found to promote tumour growth via a previously uncharacterised signalling mechanism. These findings could lead to the development of novel therapeutic strategies for breast cancers." @default.
- W2965349360 created "2019-08-13" @default.
- W2965349360 creator A5060118604 @default.
- W2965349360 date "2019-07-29" @default.
- W2965349360 modified "2023-09-28" @default.
- W2965349360 title "The role of INPP4B overexpression in breast cancer pathogenesis" @default.
- W2965349360 doi "https://doi.org/10.26180/5d3eaba18c817" @default.
- W2965349360 hasPublicationYear "2019" @default.
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