Matches in SemOpenAlex for { <https://semopenalex.org/work/W2965358532> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2965358532 endingPage "381e" @default.
- W2965358532 startingPage "375e" @default.
- W2965358532 abstract "Background: Recent research has indicated that botulinum toxin type A may have an inhibitory effect on the formation of fibroblasts and thus possibly decreases the severity of scar formation. Therefore, a trial was designed to assess the effects of botulinum toxin type A on scar formation after thyroid surgery. Methods: A double-blind, randomized, controlled trial was designed. All patients underwent a preoperative survey to assess scar history. All patients underwent a total thyroidectomy, hemithyroidectomy, or parathyroidectomy through a standardized incision. At the conclusion of the case, one half of the incision was injected with botulinum toxin type A, and the other half was injected with saline (placebo). The scars were then evaluated at 4 weeks, 6 months, and 1 year postoperatively using subjective scar analysis scales. Results: A total of 40 patients were enrolled. There was no significant difference in scarring at any of the time points between the botulinum toxin type A–treated and placebo sides of the incision. A subgroup analysis was performed that examined the effects of botulinum toxin type A on those with a severe scar history. This demonstrated a significant decrease in scarring at 6 months postoperatively on the botulinum toxin type A–treated side. Conclusions: This study indicates that botulinum toxin type A administration immediately after surgical closure of a thyroid incision does not demonstrate a difference in scar outcomes compared with the control side. However, there was less scarring in subjects who had a severe scar history. This study found opposite results to a similarly designed study. Further study is required to determine the optimal use of botulinum toxin type A for wound healing. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, II." @default.
- W2965358532 created "2019-08-13" @default.
- W2965358532 creator A5008151204 @default.
- W2965358532 creator A5038125163 @default.
- W2965358532 creator A5041608016 @default.
- W2965358532 creator A5058983509 @default.
- W2965358532 creator A5067445120 @default.
- W2965358532 creator A5078076184 @default.
- W2965358532 creator A5081486513 @default.
- W2965358532 creator A5082578081 @default.
- W2965358532 date "2019-02-01" @default.
- W2965358532 modified "2023-10-18" @default.
- W2965358532 title "The Use of Botulinum Toxin Type A in the Healing of Thyroidectomy Wounds" @default.
- W2965358532 cites W1606096607 @default.
- W2965358532 cites W1971179316 @default.
- W2965358532 cites W1981358772 @default.
- W2965358532 cites W1982656188 @default.
- W2965358532 cites W1989542317 @default.
- W2965358532 cites W1991904281 @default.
- W2965358532 cites W2002587282 @default.
- W2965358532 cites W2006423508 @default.
- W2965358532 cites W2013292682 @default.
- W2965358532 cites W2020834319 @default.
- W2965358532 cites W2078003934 @default.
- W2965358532 cites W2081616349 @default.
- W2965358532 cites W2083129069 @default.
- W2965358532 cites W2087554786 @default.
- W2965358532 cites W2095659113 @default.
- W2965358532 cites W2102036660 @default.
- W2965358532 cites W2129772426 @default.
- W2965358532 cites W2151769227 @default.
- W2965358532 cites W2168747898 @default.
- W2965358532 cites W2234331248 @default.
- W2965358532 cites W37226225 @default.
- W2965358532 cites W4251347563 @default.
- W2965358532 doi "https://doi.org/10.1097/prs.0000000000005264" @default.
- W2965358532 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30688903" @default.
- W2965358532 hasPublicationYear "2019" @default.
- W2965358532 type Work @default.
- W2965358532 sameAs 2965358532 @default.
- W2965358532 citedByCount "25" @default.
- W2965358532 countsByYear W29653585322019 @default.
- W2965358532 countsByYear W29653585322020 @default.
- W2965358532 countsByYear W29653585322021 @default.
- W2965358532 countsByYear W29653585322022 @default.
- W2965358532 countsByYear W29653585322023 @default.
- W2965358532 crossrefType "journal-article" @default.
- W2965358532 hasAuthorship W2965358532A5008151204 @default.
- W2965358532 hasAuthorship W2965358532A5038125163 @default.
- W2965358532 hasAuthorship W2965358532A5041608016 @default.
- W2965358532 hasAuthorship W2965358532A5058983509 @default.
- W2965358532 hasAuthorship W2965358532A5067445120 @default.
- W2965358532 hasAuthorship W2965358532A5078076184 @default.
- W2965358532 hasAuthorship W2965358532A5081486513 @default.
- W2965358532 hasAuthorship W2965358532A5082578081 @default.
- W2965358532 hasConcept C126322002 @default.
- W2965358532 hasConcept C141071460 @default.
- W2965358532 hasConcept C142724271 @default.
- W2965358532 hasConcept C204787440 @default.
- W2965358532 hasConcept C27081682 @default.
- W2965358532 hasConcept C2777074255 @default.
- W2965358532 hasConcept C2777397205 @default.
- W2965358532 hasConcept C2777478456 @default.
- W2965358532 hasConcept C2777642821 @default.
- W2965358532 hasConcept C42219234 @default.
- W2965358532 hasConcept C526584372 @default.
- W2965358532 hasConcept C71924100 @default.
- W2965358532 hasConceptScore W2965358532C126322002 @default.
- W2965358532 hasConceptScore W2965358532C141071460 @default.
- W2965358532 hasConceptScore W2965358532C142724271 @default.
- W2965358532 hasConceptScore W2965358532C204787440 @default.
- W2965358532 hasConceptScore W2965358532C27081682 @default.
- W2965358532 hasConceptScore W2965358532C2777074255 @default.
- W2965358532 hasConceptScore W2965358532C2777397205 @default.
- W2965358532 hasConceptScore W2965358532C2777478456 @default.
- W2965358532 hasConceptScore W2965358532C2777642821 @default.
- W2965358532 hasConceptScore W2965358532C42219234 @default.
- W2965358532 hasConceptScore W2965358532C526584372 @default.
- W2965358532 hasConceptScore W2965358532C71924100 @default.
- W2965358532 hasIssue "2" @default.
- W2965358532 hasLocation W29653585321 @default.
- W2965358532 hasOpenAccess W2965358532 @default.
- W2965358532 hasPrimaryLocation W29653585321 @default.
- W2965358532 hasRelatedWork W2046557702 @default.
- W2965358532 hasRelatedWork W2048511078 @default.
- W2965358532 hasRelatedWork W2075420748 @default.
- W2965358532 hasRelatedWork W2387245843 @default.
- W2965358532 hasRelatedWork W2393365542 @default.
- W2965358532 hasRelatedWork W2748952813 @default.
- W2965358532 hasRelatedWork W3112292354 @default.
- W2965358532 hasRelatedWork W3172812805 @default.
- W2965358532 hasRelatedWork W3175590630 @default.
- W2965358532 hasRelatedWork W3213723737 @default.
- W2965358532 hasVolume "143" @default.
- W2965358532 isParatext "false" @default.
- W2965358532 isRetracted "false" @default.
- W2965358532 magId "2965358532" @default.
- W2965358532 workType "article" @default.