FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2965408026> ?p ?o ?g. }

• W2965408026 endingPage "7301" @default.
• W2965408026 startingPage "7290" @default.
• W2965408026 abstract "Electrochemical measurements of electron transfer from an electrode to proteins immobilized at protective layers of varying thickness have shown the presence of two characteristic regimes: (i) exponential (tunneling) decay of the rate constant with the distance to the electrode and (ii) a plateau region where the rate is independent of the distance to the electrode. The reaction in the plateau region is viewed as friction-controlled electron transfer, with the rate constant inversely proportional to the medium relaxation time. Fitting the rates to established theories requires medium relaxation times far exceeding common estimates and relaxation times obtained from computer simulations of the Stokes-shift dynamics. There is a significant disconnect between experimental observations and theoretical expectations. This difficulty is resolved here by allowing additional dissipative dynamics consisting of protein's low-frequency oscillations in a soft harmonic potential describing binding of the protein to the substrate. Protein translational motions modulate the electrode-protein electronic coupling, leading to a new time-scale appearing, along with the Stokes-shift relaxation time, in the pre-exponential factor of the rate constant. The new model provides a consistent account of the experimental data. The anticipated range of friction-controlled kinetics is significantly extended, since the effective relaxation time entering the rate pre-exponential factor gains an exponential dependence on the mean-square displacement of the protein. Since the mean-square displacement is proportional to temperature, the enthalpy of activation acquires a significant and nontrivial temperature dependence. The possibility of a negative reaction enthalpy is predicted." @default.
• W2965408026 created "2019-08-13" @default.
• W2965408026 creator A5003059556 @default.
• W2965408026 date "2019-08-05" @default.
• W2965408026 modified "2023-09-29" @default.
• W2965408026 title "Dynamical Effects in Protein Electrochemistry" @default.
• W2965408026 cites W1512361887 @default.
• W2965408026 cites W1544897999 @default.
• W2965408026 cites W1966624508 @default.
• W2965408026 cites W1967979368 @default.
• W2965408026 cites W1973747581 @default.
• W2965408026 cites W1985519286 @default.
• W2965408026 cites W1987374645 @default.
• W2965408026 cites W1987586112 @default.
• W2965408026 cites W1987616212 @default.
• W2965408026 cites W1998064253 @default.
• W2965408026 cites W1998941397 @default.
• W2965408026 cites W2001709194 @default.
• W2965408026 cites W2001883528 @default.
• W2965408026 cites W2003590595 @default.
• W2965408026 cites W2007772297 @default.
• W2965408026 cites W2008631597 @default.
• W2965408026 cites W2010160707 @default.
• W2965408026 cites W2014805454 @default.
• W2965408026 cites W2015363615 @default.
• W2965408026 cites W2016090732 @default.
• W2965408026 cites W2021308443 @default.
• W2965408026 cites W2022205840 @default.
• W2965408026 cites W2024872256 @default.
• W2965408026 cites W2029834077 @default.
• W2965408026 cites W2031573489 @default.
• W2965408026 cites W2031904472 @default.
• W2965408026 cites W2038108868 @default.
• W2965408026 cites W2041894087 @default.
• W2965408026 cites W2043821600 @default.
• W2965408026 cites W2046679394 @default.
• W2965408026 cites W2052846767 @default.
• W2965408026 cites W2054524275 @default.
• W2965408026 cites W2055863460 @default.
• W2965408026 cites W2056592537 @default.
• W2965408026 cites W2056688621 @default.
• W2965408026 cites W2058686920 @default.
• W2965408026 cites W2063145455 @default.
• W2965408026 cites W2065965559 @default.
• W2965408026 cites W2070159662 @default.
• W2965408026 cites W2070820417 @default.
• W2965408026 cites W2072110215 @default.
• W2965408026 cites W2072828948 @default.
• W2965408026 cites W2074768610 @default.
• W2965408026 cites W2076004384 @default.
• W2965408026 cites W2076330818 @default.
• W2965408026 cites W2076602648 @default.
• W2965408026 cites W2084526460 @default.
• W2965408026 cites W2085266415 @default.
• W2965408026 cites W2086949118 @default.
• W2965408026 cites W2088040260 @default.
• W2965408026 cites W2088909645 @default.
• W2965408026 cites W2091975638 @default.
• W2965408026 cites W2092173086 @default.
• W2965408026 cites W2097450126 @default.
• W2965408026 cites W2097522324 @default.
• W2965408026 cites W2100971786 @default.
• W2965408026 cites W2104166397 @default.
• W2965408026 cites W2105348198 @default.
• W2965408026 cites W2115615940 @default.
• W2965408026 cites W2123210368 @default.
• W2965408026 cites W2148362226 @default.
• W2965408026 cites W2211526811 @default.
• W2965408026 cites W2250847750 @default.
• W2965408026 cites W2316023309 @default.
• W2965408026 cites W2321984390 @default.
• W2965408026 cites W2438567645 @default.
• W2965408026 cites W2474022387 @default.
• W2965408026 cites W2510973594 @default.
• W2965408026 cites W2608913994 @default.
• W2965408026 cites W2735539461 @default.
• W2965408026 cites W2762968408 @default.
• W2965408026 cites W2780169351 @default.
• W2965408026 cites W2803019715 @default.
• W2965408026 cites W2809269069 @default.
• W2965408026 cites W2897805270 @default.
• W2965408026 cites W2922512504 @default.
• W2965408026 cites W2944267279 @default.
• W2965408026 cites W4250824547 @default.
• W2965408026 cites W83025536 @default.
• W2965408026 doi "https://doi.org/10.1021/acs.jpcb.9b04516" @default.
• W2965408026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31381347" @default.
• W2965408026 hasPublicationYear "2019" @default.
• W2965408026 type Work @default.
• W2965408026 sameAs 2965408026 @default.
• W2965408026 citedByCount "14" @default.
• W2965408026 countsByYear W29654080262020 @default.
• W2965408026 countsByYear W29654080262021 @default.
• W2965408026 countsByYear W29654080262022 @default.
• W2965408026 countsByYear W29654080262023 @default.
• W2965408026 crossrefType "journal-article" @default.
• W2965408026 hasAuthorship W2965408026A5003059556 @default.
• W2965408026 hasConcept C120398109 @default.

• next