FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2965420365> ?p ?o ?g. }

• W2965420365 abstract "A bstract High-throughput sequencing technologies are a proposed solution for accessing the molecular data in historic specimens. However, degraded DNA combined with the computational demands of short-read assemblies has posed significant laboratory and bioinformatics challenges. Linked-read or ‘synthetic long-read’ sequencing technologies, such as 10X Genomics, may provide a cost-effective alternative solution to assemble higher quality de novo genomes from degraded specimens. Here, we compare assembly quality (e.g., genome contiguity and completeness, presence of orthogroups) between four published genomes assembled from a single shotgun library and four deer mouse ( Peromyscus spp.) genomes assembled using 10X Genomics technology. At a similar price-point, these approaches produce vastly different assemblies, with linked-read assemblies having overall higher quality, measured by larger N50 values and greater gene content. Although not without caveats, our results suggest that linked-read sequencing technologies may represent a viable option to build de novo genomes from historic museum specimens, which may prove particularly valuable for extinct, rare, or difficult to collect taxa." @default.
• W2965420365 created "2019-08-13" @default.
• W2965420365 creator A5001413380 @default.
• W2965420365 creator A5030458261 @default.
• W2965420365 creator A5090015516 @default.
• W2965420365 date "2019-07-28" @default.
• W2965420365 modified "2023-09-23" @default.
• W2965420365 title "Higher quality de novo genome assemblies from degraded museum specimens: a linked-read approach to museomics" @default.
• W2965420365 cites W1900937478 @default.
• W2965420365 cites W1964350046 @default.
• W2965420365 cites W1966822396 @default.
• W2965420365 cites W1967080197 @default.
• W2965420365 cites W1970835031 @default.
• W2965420365 cites W1977964679 @default.
• W2965420365 cites W1987754412 @default.
• W2965420365 cites W1998541584 @default.
• W2965420365 cites W2030846608 @default.
• W2965420365 cites W2032725566 @default.
• W2965420365 cites W2036815225 @default.
• W2965420365 cites W2038686775 @default.
• W2965420365 cites W2046233233 @default.
• W2965420365 cites W2061338306 @default.
• W2965420365 cites W2074089769 @default.
• W2965420365 cites W2078272638 @default.
• W2965420365 cites W2088238164 @default.
• W2965420365 cites W2096557606 @default.
• W2965420365 cites W2103209538 @default.
• W2965420365 cites W2105067980 @default.
• W2965420365 cites W2111647009 @default.
• W2965420365 cites W2114133992 @default.
• W2965420365 cites W2124362779 @default.
• W2965420365 cites W2134259738 @default.
• W2965420365 cites W2138009108 @default.
• W2965420365 cites W2149471901 @default.
• W2965420365 cites W2163023674 @default.
• W2965420365 cites W2166654698 @default.
• W2965420365 cites W2167227133 @default.
• W2965420365 cites W2168292723 @default.
• W2965420365 cites W2179652410 @default.
• W2965420365 cites W2264578395 @default.
• W2965420365 cites W2283105747 @default.
• W2965420365 cites W2337513885 @default.
• W2965420365 cites W2396849069 @default.
• W2965420365 cites W2590583044 @default.
• W2965420365 cites W2756236522 @default.
• W2965420365 cites W2772850277 @default.
• W2965420365 cites W2773267230 @default.
• W2965420365 cites W2781497091 @default.
• W2965420365 cites W2809646241 @default.
• W2965420365 cites W2810239869 @default.
• W2965420365 cites W2898472894 @default.
• W2965420365 cites W2899788848 @default.
• W2965420365 cites W2919564569 @default.
• W2965420365 cites W2950682063 @default.
• W2965420365 cites W2952224179 @default.
• W2965420365 cites W4246617914 @default.
• W2965420365 doi "https://doi.org/10.1101/716506" @default.
• W2965420365 hasPublicationYear "2019" @default.
• W2965420365 type Work @default.
• W2965420365 sameAs 2965420365 @default.
• W2965420365 citedByCount "1" @default.
• W2965420365 countsByYear W29654203652019 @default.
• W2965420365 crossrefType "posted-content" @default.
• W2965420365 hasAuthorship W2965420365A5001413380 @default.
• W2965420365 hasAuthorship W2965420365A5030458261 @default.
• W2965420365 hasAuthorship W2965420365A5090015516 @default.
• W2965420365 hasBestOaLocation W29654203651 @default.
• W2965420365 hasConcept C101985253 @default.
• W2965420365 hasConcept C104317684 @default.
• W2965420365 hasConcept C113425843 @default.
• W2965420365 hasConcept C141231307 @default.
• W2965420365 hasConcept C150194340 @default.
• W2965420365 hasConcept C15151743 @default.
• W2965420365 hasConcept C162317418 @default.
• W2965420365 hasConcept C189206191 @default.
• W2965420365 hasConcept C18949551 @default.
• W2965420365 hasConcept C41008148 @default.
• W2965420365 hasConcept C51679486 @default.
• W2965420365 hasConcept C54355233 @default.
• W2965420365 hasConcept C70721500 @default.
• W2965420365 hasConcept C86803240 @default.
• W2965420365 hasConceptScore W2965420365C101985253 @default.
• W2965420365 hasConceptScore W2965420365C104317684 @default.
• W2965420365 hasConceptScore W2965420365C113425843 @default.
• W2965420365 hasConceptScore W2965420365C141231307 @default.
• W2965420365 hasConceptScore W2965420365C150194340 @default.
• W2965420365 hasConceptScore W2965420365C15151743 @default.
• W2965420365 hasConceptScore W2965420365C162317418 @default.
• W2965420365 hasConceptScore W2965420365C189206191 @default.
• W2965420365 hasConceptScore W2965420365C18949551 @default.
• W2965420365 hasConceptScore W2965420365C41008148 @default.
• W2965420365 hasConceptScore W2965420365C51679486 @default.
• W2965420365 hasConceptScore W2965420365C54355233 @default.
• W2965420365 hasConceptScore W2965420365C70721500 @default.
• W2965420365 hasConceptScore W2965420365C86803240 @default.
• W2965420365 hasLocation W29654203651 @default.
• W2965420365 hasLocation W29654203652 @default.
• W2965420365 hasOpenAccess W2965420365 @default.
• W2965420365 hasPrimaryLocation W29654203651 @default.
• W2965420365 hasRelatedWork W1967080197 @default.

• next