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- W2965481124 abstract "Three new brassinosteroid analogues, named sulphurenolide A, sulphurenolide B and sulphurenolide C, were isolated from the methanolic extract of fruiting bodies of Laetiporus sulphureus. Their structures were established on the basis of extensive spectroscopic analysis (1D, 2D NMR, and HRESIMS) and ECD calculation. Sulphurenolides A and B are a pair of C-20 epimer, and sulphurenolide B represents the first naturally occurring 20R-brassinosteroid. Moreover, sulphurenolides A–C are firstly reported 5-hydroxylation and homo-6-oxa derivatives of brassinosteroids from natural sources. Anti-inflammatory assay revealed that sulphurenolides B and C exhibited significant inhibitory effects on NO production in lipopolysaccharide-induced RAW264.7 cells, and sulphurenolide C showed stronger inhibition than that of positive control, minocycline." @default.
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- W2965481124 date "2019-11-01" @default.
- W2965481124 modified "2023-10-14" @default.
- W2965481124 title "Brassinosteroid analogues from the fruiting bodies of Laetiporus sulphureus and their anti-inflammatory activity" @default.
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- W2965481124 doi "https://doi.org/10.1016/j.steroids.2019.108468" @default.
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