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- W2965642169 endingPage "2223" @default.
- W2965642169 startingPage "2210" @default.
- W2965642169 abstract "Some of the most disabling aspects of mild traumatic brain injury (mTBI) include lingering deficits in executive functioning. It is known that mTBI can damage white matter tracts, but it remains unknown how this structural brain damage translates into cognitive deficits. This experiment utilized theta band phase synchrony to identify the dysfunctional neural operations that contribute to cognitive problems following mTBI. Sub-acute stage (< 2 weeks) mTBI patients (N = 52) and healthy matched controls (N = 32) completed a control-demanding task with concurrent EEG. Structural MRI was also collected. While there were no performance-specific behavioral differences between groups in the dot probe expectancy task, the degree of theta band phase synchrony immediately following injury predicted the degree of symptom recovery two months later. Although there were no differences in fractional anisotropy (FA) between groups, joint independent components analysis revealed that a smaller network of lower FA-valued voxels contributed to a diminished frontal theta phase synchrony network in the mTBI group. This finding suggests that frontal theta band markers of cognitive control are sensitive to sub-threshold structural aberrations following mTBI." @default.
- W2965642169 created "2019-08-13" @default.
- W2965642169 creator A5016787454 @default.
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- W2965642169 creator A5038046589 @default.
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- W2965642169 creator A5060087829 @default.
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- W2965642169 creator A5083667156 @default.
- W2965642169 date "2019-07-31" @default.
- W2965642169 modified "2023-10-06" @default.
- W2965642169 title "Joint analysis of frontal theta synchrony and white matter following mild traumatic brain injury" @default.
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- W2965642169 doi "https://doi.org/10.1007/s11682-019-00171-y" @default.