FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2965860470> ?p ?o ?g. }

• W2965860470 endingPage "495" @default.
• W2965860470 startingPage "486" @default.
• W2965860470 abstract "Background/Aims Information about familial aggregation of inflammatory bowel disease (IBD) in Asia is limited. We aimed to analyze the prevalence and risk of familial IBD in an Indian cohort and compare familial and sporadic cases. Methods Familial IBD cases were identified from a large prospectively maintained IBD registry. The prevalence of IBD in first- and seconddegree relatives of index cases was evaluated. The disease behavior was compared to that of sporadic cases. Results Total 3,553 patients (ulcerative colitis [UC], 2,053; Crohn’s disease [CD], 1,500) were included. Familial IBD was noted in 4.13% of CD and 4.34% of UC patients. Family history was commoner in pediatric group (< 18 years) (P= 0.0002; odds ratio [OR], 2.8; 95% confidence interval [CI], 1.6-4.8). Majority had paternal transmission (UC, 67.42%; CD, 70.97%). Concordance of disease type was higher in UC (79.7%) compared to CD (37.1%). Familial IBD was associated with higher cumulative relapse rate (CD, P< 0.001; UC, P< 0.001), higher cumulative rate of surgery (CD, P< 0.001; UC, P< 0.001) and higher rate of biologic use (CD, P= 0.010; UC, P= 0.015). Pan-colitis was higher in familial UC (P= 0.003; OR, 1.935; 95% CI, 1.248-3.000). Fistulizing disease was commoner in familial CD (P= 0.041; OR, 2.044; 95% CI, 1.030-4.056). Conclusions The prevalence of familial IBD in India appears comparable to rest of Asia but lower than the West. It is associated with a younger age of onset, higher incidence of pan-colitis in UC and fistulizing complications in CD. Familial IBD has higher cumulative relapse, surgery and biologic use rates. Hence, family history of IBD could have important prognostic implications. Keywords: Inflammatory bowel disease; Colitis, ulcerative; Crohn disease" @default.
• W2965860470 created "2019-08-13" @default.
• W2965860470 creator A5002607987 @default.
• W2965860470 creator A5008246672 @default.
• W2965860470 creator A5033506939 @default.
• W2965860470 creator A5040367060 @default.
• W2965860470 creator A5051473333 @default.
• W2965860470 date "2019-10-31" @default.
• W2965860470 modified "2023-10-03" @default.
• W2965860470 title "Familial aggregation of inflammatory bowel disease in India: prevalence, risks and impact on disease behavior" @default.
• W2965860470 cites W1236393439 @default.
• W2965860470 cites W1556100818 @default.
• W2965860470 cites W1904655665 @default.
• W2965860470 cites W1966419516 @default.
• W2965860470 cites W1968067289 @default.
• W2965860470 cites W1971104055 @default.
• W2965860470 cites W1975761055 @default.
• W2965860470 cites W1979948289 @default.
• W2965860470 cites W1981099603 @default.
• W2965860470 cites W1990694932 @default.
• W2965860470 cites W1991724593 @default.
• W2965860470 cites W1991987314 @default.
• W2965860470 cites W1993295283 @default.
• W2965860470 cites W1999712740 @default.
• W2965860470 cites W2013078570 @default.
• W2965860470 cites W2013843556 @default.
• W2965860470 cites W201464490 @default.
• W2965860470 cites W2017967205 @default.
• W2965860470 cites W2018518908 @default.
• W2965860470 cites W2031035500 @default.
• W2965860470 cites W2032041705 @default.
• W2965860470 cites W2033275384 @default.
• W2965860470 cites W2038876182 @default.
• W2965860470 cites W2047338785 @default.
• W2965860470 cites W2051653937 @default.
• W2965860470 cites W2067733990 @default.
• W2965860470 cites W2071774207 @default.
• W2965860470 cites W2078376050 @default.
• W2965860470 cites W2105795048 @default.
• W2965860470 cites W2106183074 @default.
• W2965860470 cites W2107537096 @default.
• W2965860470 cites W2116989960 @default.
• W2965860470 cites W2120522488 @default.
• W2965860470 cites W2120712876 @default.
• W2965860470 cites W2138474643 @default.
• W2965860470 cites W2142252231 @default.
• W2965860470 cites W2144798387 @default.
• W2965860470 cites W2150235251 @default.
• W2965860470 cites W2158507534 @default.
• W2965860470 cites W2171613149 @default.
• W2965860470 cites W2182578492 @default.
• W2965860470 cites W2303775789 @default.
• W2965860470 cites W2337711722 @default.
• W2965860470 cites W2469856006 @default.
• W2965860470 cites W2523706394 @default.
• W2965860470 cites W2545556066 @default.
• W2965860470 cites W2604483966 @default.
• W2965860470 cites W2626596346 @default.
• W2965860470 cites W2900641451 @default.
• W2965860470 cites W4210662453 @default.
• W2965860470 cites W4239222201 @default.
• W2965860470 cites W87870251 @default.
• W2965860470 doi "https://doi.org/10.5217/ir.2018.00174" @default.
• W2965860470 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6821951" @default.
• W2965860470 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31370386" @default.
• W2965860470 hasPublicationYear "2019" @default.
• W2965860470 type Work @default.
• W2965860470 sameAs 2965860470 @default.
• W2965860470 citedByCount "15" @default.
• W2965860470 countsByYear W29658604702020 @default.
• W2965860470 countsByYear W29658604702021 @default.
• W2965860470 countsByYear W29658604702022 @default.
• W2965860470 crossrefType "journal-article" @default.
• W2965860470 hasAuthorship W2965860470A5002607987 @default.
• W2965860470 hasAuthorship W2965860470A5008246672 @default.
• W2965860470 hasAuthorship W2965860470A5033506939 @default.
• W2965860470 hasAuthorship W2965860470A5040367060 @default.
• W2965860470 hasAuthorship W2965860470A5051473333 @default.
• W2965860470 hasBestOaLocation W29658604701 @default.
• W2965860470 hasConcept C126322002 @default.
• W2965860470 hasConcept C156957248 @default.
• W2965860470 hasConcept C160798450 @default.
• W2965860470 hasConcept C2778260677 @default.
• W2965860470 hasConcept C2779134260 @default.
• W2965860470 hasConcept C2780479503 @default.
• W2965860470 hasConcept C2781179581 @default.
• W2965860470 hasConcept C44249647 @default.
• W2965860470 hasConcept C71924100 @default.
• W2965860470 hasConcept C72563966 @default.
• W2965860470 hasConcept C90924648 @default.
• W2965860470 hasConceptScore W2965860470C126322002 @default.
• W2965860470 hasConceptScore W2965860470C156957248 @default.
• W2965860470 hasConceptScore W2965860470C160798450 @default.
• W2965860470 hasConceptScore W2965860470C2778260677 @default.
• W2965860470 hasConceptScore W2965860470C2779134260 @default.
• W2965860470 hasConceptScore W2965860470C2780479503 @default.
• W2965860470 hasConceptScore W2965860470C2781179581 @default.
• W2965860470 hasConceptScore W2965860470C44249647 @default.

• next