FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2965920543> ?p ?o ?g. }

• W2965920543 endingPage "1693" @default.
• W2965920543 startingPage "1689" @default.
• W2965920543 abstract "Caffeic acid phenethyl ester (CAPE), an active polyphenolic component of honeybee propolis, has been demonstrated to have many medicinal properties. However, the antitumor effect and mechanism of CAPE on laryngeal carcinoma cells have not been examined. In this study, we treated HEp2 cells with various concentration of CAPE, and the results showed that CAPE can reduce the viability of HEp2 cells with IC50 values of 23.8 ± 0.7 µM for 72 h. Meanwhile, CAPE significantly inhibited activation of signal transducer and activator of transcription (Stat)3 in a concentration dependent manner in HEp2 cells and regulated the expression and transcription of Plk1. AG490, a specific Stat3 inhibitor, not only inhibited the activation and expression of Stat3, but also inhibited the expression of Plk1 in HEp2 cells, so Stat3 was probably involved in the regulation of Plk1 in HEp2 cells. In addition, treatment of CAPE leaded to a blockage of cell cycle in S phase in HEp2 cells. Therefore, CAPE inhibited the proliferation of HEp2 Cells probably by regulating Stat3/Plk1 pathway and inducing S phase arrest." @default.
• W2965920543 created "2019-08-13" @default.
• W2965920543 creator A5012087277 @default.
• W2965920543 creator A5055889919 @default.
• W2965920543 creator A5056125182 @default.
• W2965920543 creator A5060107207 @default.
• W2965920543 creator A5069625184 @default.
• W2965920543 creator A5080125836 @default.
• W2965920543 date "2019-10-01" @default.
• W2965920543 modified "2023-10-13" @default.
• W2965920543 title "Caffeic Acid Phenethyl Ester Inhibits the Proliferation of HEp2 Cells by Regulating Stat3/Plk1 Pathway and Inducing S Phase Arrest" @default.
• W2965920543 cites W1966025347 @default.
• W2965920543 cites W1975776530 @default.
• W2965920543 cites W2006663083 @default.
• W2965920543 cites W2013824927 @default.
• W2965920543 cites W2036238945 @default.
• W2965920543 cites W2039347141 @default.
• W2965920543 cites W2053050231 @default.
• W2965920543 cites W2063461424 @default.
• W2965920543 cites W2067179898 @default.
• W2965920543 cites W2081120437 @default.
• W2965920543 cites W2086579355 @default.
• W2965920543 cites W2087832022 @default.
• W2965920543 cites W2105187139 @default.
• W2965920543 cites W2105269215 @default.
• W2965920543 cites W2131420159 @default.
• W2965920543 cites W2146572998 @default.
• W2965920543 cites W2274041246 @default.
• W2965920543 cites W2883461704 @default.
• W2965920543 cites W2890139110 @default.
• W2965920543 cites W2901659739 @default.
• W2965920543 doi "https://doi.org/10.1248/bpb.b19-00315" @default.
• W2965920543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31366853" @default.
• W2965920543 hasPublicationYear "2019" @default.
• W2965920543 type Work @default.
• W2965920543 sameAs 2965920543 @default.
• W2965920543 citedByCount "11" @default.
• W2965920543 countsByYear W29659205432020 @default.
• W2965920543 countsByYear W29659205432021 @default.
• W2965920543 countsByYear W29659205432022 @default.
• W2965920543 countsByYear W29659205432023 @default.
• W2965920543 crossrefType "journal-article" @default.
• W2965920543 hasAuthorship W2965920543A5012087277 @default.
• W2965920543 hasAuthorship W2965920543A5055889919 @default.
• W2965920543 hasAuthorship W2965920543A5056125182 @default.
• W2965920543 hasAuthorship W2965920543A5060107207 @default.
• W2965920543 hasAuthorship W2965920543A5069625184 @default.
• W2965920543 hasAuthorship W2965920543A5080125836 @default.
• W2965920543 hasBestOaLocation W29659205431 @default.
• W2965920543 hasConcept C105696609 @default.
• W2965920543 hasConcept C146276462 @default.
• W2965920543 hasConcept C171958077 @default.
• W2965920543 hasConcept C185592680 @default.
• W2965920543 hasConcept C190283241 @default.
• W2965920543 hasConcept C2776992468 @default.
• W2965920543 hasConcept C2778004101 @default.
• W2965920543 hasConcept C2778224086 @default.
• W2965920543 hasConcept C2778277574 @default.
• W2965920543 hasConcept C2778923194 @default.
• W2965920543 hasConcept C29537977 @default.
• W2965920543 hasConcept C55493867 @default.
• W2965920543 hasConcept C62112901 @default.
• W2965920543 hasConcept C86803240 @default.
• W2965920543 hasConcept C95444343 @default.
• W2965920543 hasConceptScore W2965920543C105696609 @default.
• W2965920543 hasConceptScore W2965920543C146276462 @default.
• W2965920543 hasConceptScore W2965920543C171958077 @default.
• W2965920543 hasConceptScore W2965920543C185592680 @default.
• W2965920543 hasConceptScore W2965920543C190283241 @default.
• W2965920543 hasConceptScore W2965920543C2776992468 @default.
• W2965920543 hasConceptScore W2965920543C2778004101 @default.
• W2965920543 hasConceptScore W2965920543C2778224086 @default.
• W2965920543 hasConceptScore W2965920543C2778277574 @default.
• W2965920543 hasConceptScore W2965920543C2778923194 @default.
• W2965920543 hasConceptScore W2965920543C29537977 @default.
• W2965920543 hasConceptScore W2965920543C55493867 @default.
• W2965920543 hasConceptScore W2965920543C62112901 @default.
• W2965920543 hasConceptScore W2965920543C86803240 @default.
• W2965920543 hasConceptScore W2965920543C95444343 @default.
• W2965920543 hasIssue "10" @default.
• W2965920543 hasLocation W29659205431 @default.
• W2965920543 hasLocation W29659205432 @default.
• W2965920543 hasOpenAccess W2965920543 @default.
• W2965920543 hasPrimaryLocation W29659205431 @default.
• W2965920543 hasRelatedWork W1983974405 @default.
• W2965920543 hasRelatedWork W1985198089 @default.
• W2965920543 hasRelatedWork W2358007372 @default.
• W2965920543 hasRelatedWork W2367374011 @default.
• W2965920543 hasRelatedWork W2374987808 @default.
• W2965920543 hasRelatedWork W2383141715 @default.
• W2965920543 hasRelatedWork W2891863700 @default.
• W2965920543 hasRelatedWork W2965920543 @default.
• W2965920543 hasRelatedWork W3024783490 @default.
• W2965920543 hasRelatedWork W2004445097 @default.
• W2965920543 hasVolume "42" @default.
• W2965920543 isParatext "false" @default.
• W2965920543 isRetracted "false" @default.
• W2965920543 magId "2965920543" @default.

• next