Matches in SemOpenAlex for { <https://semopenalex.org/work/W2965930178> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2965930178 abstract "The emergence of drug-resistant tuberculosis is a growing disease worldwide. The lack of safe and effective drugs, together with the frequent development of adverse drug reactions could result in worse condition. Therefore, new drugs able to booster the current tuberculosis treatment regimen are urgently required. Novel drugs that are effective and safe against Mycobacterium tuberculosis are required to reduce the number of drugs and the duration of treatment in both drug-susceptible tuberculosis and multi-drug-resistant tuberculosis. Due to increased number of multidrugresistant and extensively drug-resistant strains and the ineffectiveness of the current treatment against latent tuberculosis are challenges to be overcome in future. The scenario of drug discovery becomes upsetting when it is considered that the number of new drugs does not increase proportionally to the emergence of drug resistance. In this review, we will demonstrate the recent advances in anti-tubercular drug discovery, centre of attention on the research of compounds with potent anti-tuberculosis activity against multidrug-resistant tuberculosis strains. Although, the best treatment regimen for achieving better results and preventing adverse drug reactions remains yet to be determined, with safety concerns regarding cardiac events due to QT prolongation still to be addressed. Therefore a simple and short treatment with higher efficacy, and lesser adverse drug reactions and drug-drug interaction is expected for patients with multidrug-resistant and extensively drug-resistant tuberculosis." @default.
- W2965930178 created "2019-08-13" @default.
- W2965930178 creator A5017765202 @default.
- W2965930178 creator A5028358118 @default.
- W2965930178 date "2019-01-01" @default.
- W2965930178 modified "2023-09-24" @default.
- W2965930178 title "Recent Advances in Tuberculosis Drug Development" @default.
- W2965930178 doi "https://doi.org/10.31838/ijprt/08.02.01" @default.
- W2965930178 hasPublicationYear "2019" @default.
- W2965930178 type Work @default.
- W2965930178 sameAs 2965930178 @default.
- W2965930178 citedByCount "0" @default.
- W2965930178 crossrefType "journal-article" @default.
- W2965930178 hasAuthorship W2965930178A5017765202 @default.
- W2965930178 hasAuthorship W2965930178A5028358118 @default.
- W2965930178 hasBestOaLocation W29659301781 @default.
- W2965930178 hasConcept C114851261 @default.
- W2965930178 hasConcept C141071460 @default.
- W2965930178 hasConcept C142724271 @default.
- W2965930178 hasConcept C177713679 @default.
- W2965930178 hasConcept C197934379 @default.
- W2965930178 hasConcept C2777107064 @default.
- W2965930178 hasConcept C2777975735 @default.
- W2965930178 hasConcept C2780035454 @default.
- W2965930178 hasConcept C2780544761 @default.
- W2965930178 hasConcept C2781069245 @default.
- W2965930178 hasConcept C2781413609 @default.
- W2965930178 hasConcept C71924100 @default.
- W2965930178 hasConcept C86803240 @default.
- W2965930178 hasConcept C89423630 @default.
- W2965930178 hasConcept C98274493 @default.
- W2965930178 hasConceptScore W2965930178C114851261 @default.
- W2965930178 hasConceptScore W2965930178C141071460 @default.
- W2965930178 hasConceptScore W2965930178C142724271 @default.
- W2965930178 hasConceptScore W2965930178C177713679 @default.
- W2965930178 hasConceptScore W2965930178C197934379 @default.
- W2965930178 hasConceptScore W2965930178C2777107064 @default.
- W2965930178 hasConceptScore W2965930178C2777975735 @default.
- W2965930178 hasConceptScore W2965930178C2780035454 @default.
- W2965930178 hasConceptScore W2965930178C2780544761 @default.
- W2965930178 hasConceptScore W2965930178C2781069245 @default.
- W2965930178 hasConceptScore W2965930178C2781413609 @default.
- W2965930178 hasConceptScore W2965930178C71924100 @default.
- W2965930178 hasConceptScore W2965930178C86803240 @default.
- W2965930178 hasConceptScore W2965930178C89423630 @default.
- W2965930178 hasConceptScore W2965930178C98274493 @default.
- W2965930178 hasIssue "2" @default.
- W2965930178 hasLocation W29659301781 @default.
- W2965930178 hasOpenAccess W2965930178 @default.
- W2965930178 hasPrimaryLocation W29659301781 @default.
- W2965930178 hasRelatedWork W1986605018 @default.
- W2965930178 hasRelatedWork W1988061233 @default.
- W2965930178 hasRelatedWork W2011358501 @default.
- W2965930178 hasRelatedWork W2132468620 @default.
- W2965930178 hasRelatedWork W2190838350 @default.
- W2965930178 hasRelatedWork W2300465082 @default.
- W2965930178 hasRelatedWork W2359554423 @default.
- W2965930178 hasRelatedWork W2435986190 @default.
- W2965930178 hasRelatedWork W2466483069 @default.
- W2965930178 hasRelatedWork W2468095797 @default.
- W2965930178 hasRelatedWork W2471509732 @default.
- W2965930178 hasRelatedWork W2790605859 @default.
- W2965930178 hasRelatedWork W2791214549 @default.
- W2965930178 hasRelatedWork W2797869638 @default.
- W2965930178 hasRelatedWork W2993020823 @default.
- W2965930178 hasRelatedWork W3005252851 @default.
- W2965930178 hasRelatedWork W3021896690 @default.
- W2965930178 hasRelatedWork W3040358078 @default.
- W2965930178 hasRelatedWork W1744139790 @default.
- W2965930178 hasRelatedWork W2623171878 @default.
- W2965930178 hasVolume "8" @default.
- W2965930178 isParatext "false" @default.
- W2965930178 isRetracted "false" @default.
- W2965930178 magId "2965930178" @default.
- W2965930178 workType "article" @default.