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- W2966453421 abstract "Objectives The aim of this study was to investigate the influence of xenon-based anesthesia on somatosensory-evoked potentials. Design Observational cohort study. Setting University hospital. Participants Twenty subsequent adult patients undergoing elective carotid endarterectomy. Interventions Xenon-based anesthesia. Measurements and Main Results Cortical-evoked responses to median nerve stimulation were quantified by measurement of the amplitude and latency of the N20 wave, which are typically assessed during carotid surgery to detect intraoperative cerebral hypoperfusion and ischemia. Primary (N20 amplitude and latency) and secondary (mean arterial pressure, norepinephrine requirements and depth of anesthesia) were assessed during (1) propofol/remifentanil and (2) subsequent xenon/remifentanil anesthesia. Xenon at an inspiratory fraction of 62.5 ± 7% decreased norepinephrine requirement (0.067 ± 0.04 v 0.028 ± 0.02 µg/kg/min, p Conclusions Xenon influences somatosensory-evoked potentials measurement by reducing N20 wave amplitude but not latency. When xenon is considered as an anesthetic for carotid endarterectomy, wash-in needs to be completed before carotid surgery is commenced to provide stable baseline somatosensory-evoked potential measurement." @default.
- W2966453421 created "2019-08-13" @default.
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- W2966453421 date "2020-01-01" @default.
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- W2966453421 title "The Effect of Xenon-Based Anesthesia on Somatosensory-Evoked Potentials in Patients Undergoing Carotid Endarterectomy" @default.
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- W2966453421 doi "https://doi.org/10.1053/j.jvca.2019.07.148" @default.
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