Matches in SemOpenAlex for { <https://semopenalex.org/work/W2966680863> ?p ?o ?g. }
- W2966680863 endingPage "12802" @default.
- W2966680863 startingPage "12790" @default.
- W2966680863 abstract "Multicomponent self-assembly of Mn2(CO)10, a bis-chelating aminoquinonato (ON∩ON) bridge (L), and an ester/amide-functionalized flexible neutral ditopic linker (L′) has resulted into the formation of M2LL′-type manganese(I)-based dinuclear metallastirrups of general formula [{(CO)3Mn(μ-η4-L)Mn(CO)3}(μ-L′)] (1–10). Compounds 1–10 were accomplished via orthogonal bonding of the aminoquinone ligand (2,5-bis(n-butylamino)-1,4-benzoquinone/2,5-bis(phenethylamino)-1,4-benzoquinone) and ditopic pyridyl ligand to manganese carbonyl. The resultant metallastirrups were characterized using elemental analyses and IR, UV–vis, 1H NMR, and electrospray ionization-mass spectroscopic techniques. The molecular structure of 6 was confirmed by single-crystal X-ray diffraction methods. Furthermore, molecular recognition capabilities of 1, 5, 7, and 9 were evaluated with aromatic compounds containing hydroxy/amine functionalities. Anticancer activities of compounds 1−3, 5−7, 9, and 10 were investigated against three cancer cell lines, that is, lung (A549), colon (HCT-15), and cervical (HeLa) as well as on normal cells (HEK 293). Compound 9 showed a broad-spectrum inhibition toward these cancer cells upon exposure to visible light. The myoglobin assay was performed using UV–vis absorption spectroscopy to investigate the visible-light-triggered CO release from 5 and 9 that could be related to their ability to effectively inhibit cancer cells. In addition, morphological studies confirmed the induction of autophagy due to the treatment of cancer cells using compound 9." @default.
- W2966680863 created "2019-08-13" @default.
- W2966680863 creator A5013911436 @default.
- W2966680863 creator A5014963488 @default.
- W2966680863 creator A5019723040 @default.
- W2966680863 creator A5060399191 @default.
- W2966680863 creator A5068509816 @default.
- W2966680863 date "2019-07-26" @default.
- W2966680863 modified "2023-10-11" @default.
- W2966680863 title "Single-Pot Self-Assembly of Heteroleptic Mn(I)-Based Aminoquinonato-Bridged Ester/Amide-Functionalized Dinuclear Metallastirrups: Potential Anticancer and Visible-Light-Triggered CORMs" @default.
- W2966680863 cites W153335941 @default.
- W2966680863 cites W1718978953 @default.
- W2966680863 cites W1795782978 @default.
- W2966680863 cites W1967143694 @default.
- W2966680863 cites W1970159920 @default.
- W2966680863 cites W1970684567 @default.
- W2966680863 cites W1975246679 @default.
- W2966680863 cites W1976254490 @default.
- W2966680863 cites W1977029846 @default.
- W2966680863 cites W1983683512 @default.
- W2966680863 cites W1989712133 @default.
- W2966680863 cites W1990711291 @default.
- W2966680863 cites W1995488137 @default.
- W2966680863 cites W1996227152 @default.
- W2966680863 cites W1996733738 @default.
- W2966680863 cites W1999839042 @default.
- W2966680863 cites W2004889129 @default.
- W2966680863 cites W2007821559 @default.
- W2966680863 cites W2011330420 @default.
- W2966680863 cites W2011966001 @default.
- W2966680863 cites W2014482614 @default.
- W2966680863 cites W2018953463 @default.
- W2966680863 cites W2020403270 @default.
- W2966680863 cites W2024786531 @default.
- W2966680863 cites W2029483113 @default.
- W2966680863 cites W2035960780 @default.
- W2966680863 cites W2039312580 @default.
- W2966680863 cites W2039914623 @default.
- W2966680863 cites W2042590692 @default.
- W2966680863 cites W2043166802 @default.
- W2966680863 cites W2051060354 @default.
- W2966680863 cites W2052066414 @default.
- W2966680863 cites W2055106534 @default.
- W2966680863 cites W2057133008 @default.
- W2966680863 cites W2059020082 @default.
- W2966680863 cites W2063919294 @default.
- W2966680863 cites W2064010970 @default.
- W2966680863 cites W2065753886 @default.
- W2966680863 cites W2066567032 @default.
- W2966680863 cites W2068371586 @default.
- W2966680863 cites W2069210041 @default.
- W2966680863 cites W2070087900 @default.
- W2966680863 cites W2075586791 @default.
- W2966680863 cites W2077091994 @default.
- W2966680863 cites W2078408605 @default.
- W2966680863 cites W2082000155 @default.
- W2966680863 cites W2091936495 @default.
- W2966680863 cites W2093220493 @default.
- W2966680863 cites W2093403996 @default.
- W2966680863 cites W2101084723 @default.
- W2966680863 cites W2105204874 @default.
- W2966680863 cites W2119388539 @default.
- W2966680863 cites W2124670769 @default.
- W2966680863 cites W2131184266 @default.
- W2966680863 cites W2131350133 @default.
- W2966680863 cites W2142664741 @default.
- W2966680863 cites W2151003442 @default.
- W2966680863 cites W2170942810 @default.
- W2966680863 cites W2172750220 @default.
- W2966680863 cites W2213147035 @default.
- W2966680863 cites W2234255680 @default.
- W2966680863 cites W2238911903 @default.
- W2966680863 cites W2259649099 @default.
- W2966680863 cites W2283801716 @default.
- W2966680863 cites W2288692284 @default.
- W2966680863 cites W2312218940 @default.
- W2966680863 cites W2314541876 @default.
- W2966680863 cites W2316935074 @default.
- W2966680863 cites W2319105492 @default.
- W2966680863 cites W2320782215 @default.
- W2966680863 cites W2324549725 @default.
- W2966680863 cites W2325082067 @default.
- W2966680863 cites W2326752902 @default.
- W2966680863 cites W2330918455 @default.
- W2966680863 cites W2331231369 @default.
- W2966680863 cites W2331419692 @default.
- W2966680863 cites W2395840227 @default.
- W2966680863 cites W2469936327 @default.
- W2966680863 cites W2516547036 @default.
- W2966680863 cites W2535659243 @default.
- W2966680863 cites W2601656695 @default.
- W2966680863 cites W2605593378 @default.
- W2966680863 cites W2605999615 @default.
- W2966680863 cites W2606003973 @default.
- W2966680863 cites W2609881085 @default.
- W2966680863 cites W2611101105 @default.
- W2966680863 cites W2622159360 @default.
- W2966680863 cites W2724660973 @default.