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- W2966879040 abstract "BackgroundMeasles is a highly contagious and a vaccine-preventable disease. On 14 August 2015, a measles outbreak was reported in Langkat District, North Sumatra province of Indonesia. To investigate the risk factors of the outbreak and to recommend control measures, an epidemiological investigation was undertaken.MethodA 1:1 matched case-control study was conducted. All suspect and confirmed cases were recruited and included. Controls were healthy neighbors of cases, matched for age and gender. House-to-house search for cases was carried out. Structural interviews were conducted to solicit demographic data, clinical data, as well as the risk factors. A two-step logistic regression was employed to assess the potential risk factors associated with the infection.ResultsDuring 20 July to 25 September 2015, a total of 28 measles cases were identified with no death. All tested blood samples were positive for measles-specific IgM antibodies confirming the outbreak. All cases presented with fever and rash; cough (80%), coryza (65%), and conjunctivitis (25%). The attack rate (AR) was 14.1% (age ranged between 1 and 14 years old), the highest AR (50.0%) occurred among those aged 1–4 years. In multivariate model, those who have not received measless vaccication and those who had contact with a measles case had higher odds of having infection, with adjusted odds ratio (aOR): 2.31 (95%CI: 1.22–4.27) and aOR: 1.15 (95%CI: 1.12–3.70), respectively.ConclusionsBeing unvaccinated and having a contact history increased the risk of measles are two risk factors of measles infection. A mass measles immunization to the school children was undertaken and a strict measles surveillance and notification system were recommended to control the transmission in the future." @default.
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- W2966879040 date "2020-03-01" @default.
- W2966879040 modified "2023-10-17" @default.
- W2966879040 title "Being unvaccinated and contact with measles cases as the risk factors of measles outbreak, North Sumatera, Indonesia" @default.
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- W2966879040 doi "https://doi.org/10.1016/j.cegh.2019.08.006" @default.
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