Matches in SemOpenAlex for { <https://semopenalex.org/work/W2966952952> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2966952952 endingPage "376" @default.
- W2966952952 startingPage "370" @default.
- W2966952952 abstract "Burn patients frequently require autograft harvesting to facilitate wound healing, often resulting in significant pain. Liposomal bupivacaine is indicated for administration into a surgical site to produce postsurgical analgesia. The objective of this study was to evaluate efficacy, safety, and duration of postoperative analgesia with liposomal bupivacaine for donor site pain in burn patients. This was an observational, case–control study including adult patients with <20% total body surface area (TBSA) burned who received liposomal bupivacaine for postoperative pain management after autograft harvesting from lower extremity donor site(s). Patients from the case group were matched to historical control patients treated with traditional pain management. The primary outcome was the cumulative pain scores on postoperative day one measured by the area under the curve (AUC0–24). Secondary outcomes included AUC0–72, total milligram morphine equivalents (MME), length of stay, and adverse events. Data were collected in 36 patients who received liposomal bupivacaine, with 21 patients eligible for matching to historical controls. Patients included in the intervention and control groups were well-matched at baseline. Patients in the intervention group had a significantly lower median (IQR) AUC0–24 [578 (408,740) vs. 680 (544,803); p = 0.05] and shorter length of stay [4 days (1,9.5) vs. 6 days (318); p = 0.01]. No differences in adverse events related to the administration of liposomal bupivacaine or opioid-related adverse events were observed. Results indicate liposomal bupivacaine is safe and effective in burn patients. The results of this study add to the limited body of literature examining efficacy in this population." @default.
- W2966952952 created "2019-08-22" @default.
- W2966952952 creator A5009637931 @default.
- W2966952952 creator A5014795482 @default.
- W2966952952 creator A5017882056 @default.
- W2966952952 creator A5030444201 @default.
- W2966952952 creator A5035250203 @default.
- W2966952952 creator A5044979009 @default.
- W2966952952 creator A5062538265 @default.
- W2966952952 date "2020-03-01" @default.
- W2966952952 modified "2023-09-26" @default.
- W2966952952 title "A prospective analysis describing the innovative use of liposomal bupivacaine in burn patients" @default.
- W2966952952 cites W1986056295 @default.
- W2966952952 cites W1993424947 @default.
- W2966952952 cites W2032088839 @default.
- W2966952952 cites W2087046377 @default.
- W2966952952 cites W2095175406 @default.
- W2966952952 cites W2130271602 @default.
- W2966952952 cites W2316519281 @default.
- W2966952952 cites W2323650991 @default.
- W2966952952 cites W2338918802 @default.
- W2966952952 cites W2526457179 @default.
- W2966952952 cites W2603392745 @default.
- W2966952952 cites W2773296735 @default.
- W2966952952 cites W2922505700 @default.
- W2966952952 cites W4211036686 @default.
- W2966952952 doi "https://doi.org/10.1016/j.burns.2019.07.031" @default.
- W2966952952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31420265" @default.
- W2966952952 hasPublicationYear "2020" @default.
- W2966952952 type Work @default.
- W2966952952 sameAs 2966952952 @default.
- W2966952952 citedByCount "4" @default.
- W2966952952 countsByYear W29669529522021 @default.
- W2966952952 countsByYear W29669529522022 @default.
- W2966952952 countsByYear W29669529522023 @default.
- W2966952952 crossrefType "journal-article" @default.
- W2966952952 hasAuthorship W2966952952A5009637931 @default.
- W2966952952 hasAuthorship W2966952952A5014795482 @default.
- W2966952952 hasAuthorship W2966952952A5017882056 @default.
- W2966952952 hasAuthorship W2966952952A5030444201 @default.
- W2966952952 hasAuthorship W2966952952A5035250203 @default.
- W2966952952 hasAuthorship W2966952952A5044979009 @default.
- W2966952952 hasAuthorship W2966952952A5062538265 @default.
- W2966952952 hasBestOaLocation W29669529522 @default.
- W2966952952 hasConcept C126322002 @default.
- W2966952952 hasConcept C141071460 @default.
- W2966952952 hasConcept C170493617 @default.
- W2966952952 hasConcept C197934379 @default.
- W2966952952 hasConcept C23131810 @default.
- W2966952952 hasConcept C2777389121 @default.
- W2966952952 hasConcept C2780820201 @default.
- W2966952952 hasConcept C2781063702 @default.
- W2966952952 hasConcept C2781328992 @default.
- W2966952952 hasConcept C2993242423 @default.
- W2966952952 hasConcept C42219234 @default.
- W2966952952 hasConcept C71924100 @default.
- W2966952952 hasConceptScore W2966952952C126322002 @default.
- W2966952952 hasConceptScore W2966952952C141071460 @default.
- W2966952952 hasConceptScore W2966952952C170493617 @default.
- W2966952952 hasConceptScore W2966952952C197934379 @default.
- W2966952952 hasConceptScore W2966952952C23131810 @default.
- W2966952952 hasConceptScore W2966952952C2777389121 @default.
- W2966952952 hasConceptScore W2966952952C2780820201 @default.
- W2966952952 hasConceptScore W2966952952C2781063702 @default.
- W2966952952 hasConceptScore W2966952952C2781328992 @default.
- W2966952952 hasConceptScore W2966952952C2993242423 @default.
- W2966952952 hasConceptScore W2966952952C42219234 @default.
- W2966952952 hasConceptScore W2966952952C71924100 @default.
- W2966952952 hasIssue "2" @default.
- W2966952952 hasLocation W29669529521 @default.
- W2966952952 hasLocation W29669529522 @default.
- W2966952952 hasOpenAccess W2966952952 @default.
- W2966952952 hasPrimaryLocation W29669529521 @default.
- W2966952952 hasRelatedWork W1992361843 @default.
- W2966952952 hasRelatedWork W2002578214 @default.
- W2966952952 hasRelatedWork W2022116026 @default.
- W2966952952 hasRelatedWork W2049917025 @default.
- W2966952952 hasRelatedWork W2081628824 @default.
- W2966952952 hasRelatedWork W2156524244 @default.
- W2966952952 hasRelatedWork W2171970202 @default.
- W2966952952 hasRelatedWork W2419667953 @default.
- W2966952952 hasRelatedWork W4231944436 @default.
- W2966952952 hasRelatedWork W1553783295 @default.
- W2966952952 hasVolume "46" @default.
- W2966952952 isParatext "false" @default.
- W2966952952 isRetracted "false" @default.
- W2966952952 magId "2966952952" @default.
- W2966952952 workType "article" @default.