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- W2966989360 abstract "An improved and practical method is reported here for accessing 3′,4′,5′-trifluoro-[1,1′-biphenyl]-2-amine (1), a key intermediate for Fluxapyroxad. The overall yield for the preparation of 1 was 73%, with a purity of 99.88%, after a three-step process. More importantly, this process was an improvement in the manufacture of biphenyl compounds by Suzuki–Miyaura coupling, which enabled catalyst loading as low as 0.04 mol %. This method could provide an economic and environment-friendly process leading to extensive prospects in industrial applications." @default.
- W2966989360 created "2019-08-22" @default.
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- W2966989360 date "2019-08-14" @default.
- W2966989360 modified "2023-10-14" @default.
- W2966989360 title "Efficient and Practical Synthesis of 3′,4′,5′-Trifluoro-[1,1′-biphenyl]-2-amine: A Key Intermediate of Fluxapyroxad" @default.
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- W2966989360 doi "https://doi.org/10.1021/acs.oprd.9b00208" @default.
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