FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2967436981> ?p ?o ?g. }

• W2967436981 endingPage "2678" @default.
• W2967436981 startingPage "2661" @default.
• W2967436981 abstract "As well established for patients with chronic pain, patients suffering from chronic itch also exhibit signs of peripheral and central sensitization. This has been linked to parallel neuroplastic sensitization processes. However, for chronic itch, sensitization has not yet been systematically assessed, studied, and hence validated. This review (Prospero CRD42016043002) summarizes and meta-analytically evaluates whether sensory aberrations including sensitization for itch occur in chronic itch. Databases PubMed, Embase, and Cochrane Library were searched for studies investigating somatosensory sensitivity assessment by quantitative sensory testing stimuli, including experimental cutaneous chemical pruritic provocations, in patients with chronic itch from skin/neurological conditions and compared with healthy controls. Outcomes were extracted for lesional and nonlesional skin, and risk of biases were assessed. Meta-analyses were performed when sufficient quantitative data were available. Of 4667 identified articles, 46 were included and 25 were eligible for meta-analyses. Patients (66% atopic dermatitis [AD]) were found more sensitive than the controls to histamine-evoked itch in lesional skin (standardized mean difference [SMD]: 0.66 confidence interval [CI]: 0.16-1.15), but not nonlesionally (SMD: −0.26 [CI: −0.58 to 0.06]). Cowhage did not evoke more itch in nonlesional skin of patients as compared to the controls (SMD: 0.38 [CI: −0.04 to 0.81]). For numerous other chemical provocations as well as for mechanical, thermal, and electrical stimulation paradigms, results were ambiguous or based on few studies. Patients with chronic itch are only robustly sensitized to various chemical pruritic stimuli when applied lesionally. More studies on somatosensory aberrations in chronic itch conditions other than AD are needed to establish whether sensitization is robustly present across chronic itch conditions." @default.
• W2967436981 created "2019-08-22" @default.
• W2967436981 creator A5016157357 @default.
• W2967436981 creator A5027265019 @default.
• W2967436981 creator A5032105584 @default.
• W2967436981 creator A5036711095 @default.
• W2967436981 creator A5078339011 @default.
• W2967436981 creator A5083430100 @default.
• W2967436981 date "2019-08-10" @default.
• W2967436981 modified "2023-10-09" @default.
• W2967436981 title "Itch sensitization? A systematic review of studies using quantitative sensory testing in patients with chronic itch" @default.
• W2967436981 cites W1006559644 @default.
• W2967436981 cites W1522281198 @default.
• W2967436981 cites W1532603208 @default.
• W2967436981 cites W1595172481 @default.
• W2967436981 cites W1910754645 @default.
• W2967436981 cites W1951576969 @default.
• W2967436981 cites W1964030186 @default.
• W2967436981 cites W1968974481 @default.
• W2967436981 cites W1970075861 @default.
• W2967436981 cites W1970404910 @default.
• W2967436981 cites W1971121229 @default.
• W2967436981 cites W1974079991 @default.
• W2967436981 cites W1975377094 @default.
• W2967436981 cites W1977380441 @default.
• W2967436981 cites W1978828993 @default.
• W2967436981 cites W1982134608 @default.
• W2967436981 cites W1983014867 @default.
• W2967436981 cites W1984144008 @default.
• W2967436981 cites W1988408110 @default.
• W2967436981 cites W1990820382 @default.
• W2967436981 cites W1993874766 @default.
• W2967436981 cites W1996903618 @default.
• W2967436981 cites W1996967496 @default.
• W2967436981 cites W2006363519 @default.
• W2967436981 cites W2008452682 @default.
• W2967436981 cites W2008486809 @default.
• W2967436981 cites W2010673261 @default.
• W2967436981 cites W2011367371 @default.
• W2967436981 cites W2012514045 @default.
• W2967436981 cites W2020279617 @default.
• W2967436981 cites W2022279793 @default.
• W2967436981 cites W2023711648 @default.
• W2967436981 cites W2030880840 @default.
• W2967436981 cites W2034452985 @default.
• W2967436981 cites W2034691182 @default.
• W2967436981 cites W2040792219 @default.
• W2967436981 cites W2045470823 @default.
• W2967436981 cites W2054124635 @default.
• W2967436981 cites W2055349649 @default.
• W2967436981 cites W2058376429 @default.
• W2967436981 cites W2059768248 @default.
• W2967436981 cites W2061267120 @default.
• W2967436981 cites W2062625412 @default.
• W2967436981 cites W2065246339 @default.
• W2967436981 cites W2069927357 @default.
• W2967436981 cites W2071203761 @default.
• W2967436981 cites W2077137686 @default.
• W2967436981 cites W2077885131 @default.
• W2967436981 cites W2079954055 @default.
• W2967436981 cites W2080742293 @default.
• W2967436981 cites W2083409227 @default.
• W2967436981 cites W2086182737 @default.
• W2967436981 cites W2096194006 @default.
• W2967436981 cites W2098416088 @default.
• W2967436981 cites W2100517893 @default.
• W2967436981 cites W2101665273 @default.
• W2967436981 cites W2105923823 @default.
• W2967436981 cites W2106444954 @default.
• W2967436981 cites W2108112094 @default.
• W2967436981 cites W2116230226 @default.
• W2967436981 cites W2117032899 @default.
• W2967436981 cites W2117127328 @default.
• W2967436981 cites W2119500165 @default.
• W2967436981 cites W2128692107 @default.
• W2967436981 cites W2131239942 @default.
• W2967436981 cites W2131309533 @default.
• W2967436981 cites W2131894401 @default.
• W2967436981 cites W2146263464 @default.
• W2967436981 cites W2151626900 @default.
• W2967436981 cites W2155524482 @default.
• W2967436981 cites W2160867877 @default.
• W2967436981 cites W2161388492 @default.
• W2967436981 cites W2164680396 @default.
• W2967436981 cites W2164830294 @default.
• W2967436981 cites W2167563559 @default.
• W2967436981 cites W2170313358 @default.
• W2967436981 cites W2171390525 @default.
• W2967436981 cites W2171495888 @default.
• W2967436981 cites W2171591960 @default.
• W2967436981 cites W2177655369 @default.
• W2967436981 cites W2191692978 @default.
• W2967436981 cites W2227955023 @default.
• W2967436981 cites W2260845459 @default.
• W2967436981 cites W2269577867 @default.
• W2967436981 cites W2331694814 @default.
• W2967436981 cites W2395704789 @default.
• W2967436981 cites W2401477714 @default.

• next