Matches in SemOpenAlex for { <https://semopenalex.org/work/W2967443126> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2967443126 endingPage "576" @default.
- W2967443126 startingPage "576" @default.
- W2967443126 abstract "576 OBJECTIVES: Previously other groups have demonstrated Mycoplasma hyorhinis in gastrointestinal tumors. Recently, our group reported that subjecting human cells to a M. hyorhinis protein, p37 was associated with cellular and genetic changes indicative of a more aggressive malignancy. To help elucidate cause and effect, M. hyorhinis must be present in human prostate specimens. Our objectives were to demonstrate M. hyorhinis in human prostate specimens and to evaluate the association of mycoplasmal expression with the presence of prostatic carcinoma and clinical outcomes. METHODS: Immunohistochemical staining for M. hyorhinis was performed on archival frozen prostate tissue specimens from 24 normal (BPH) controls and 26 consecutive prostate cancer patients from our tissue bank. M. hyorhinis was considered present when more than 5% of the cells were immunoreactive. As a means to confirm these results, nested PCR was performed utilizing primers for M. hyorhinis. RESULTS: M. hyorhinis was present in 69% of the tumor specimens vs. 33% of the benign specimens. These results were confirmed with nested PCR. Though not powered to detect such a difference, M hyorhinis immunoreactivity was associated with higher grades and higher stages prostatic carcinomas. CONCLUSIONS: We report the first experience of detecting M hyrohinis in human prostatic tissue. In addition, a higher correlation of M. hyrohinis immunoreactivity was noted in prostatic tumors compared to benign prostates. Currently a larger study is underway to correlate M hyrohinis infection with prostate cancer, specifically higher grade and higher stage tumors." @default.
- W2967443126 created "2019-08-22" @default.
- W2967443126 creator A5020966829 @default.
- W2967443126 creator A5024594616 @default.
- W2967443126 creator A5040870373 @default.
- W2967443126 creator A5062727443 @default.
- W2967443126 creator A5071174564 @default.
- W2967443126 creator A5082611981 @default.
- W2967443126 date "2008-05-01" @default.
- W2967443126 modified "2023-09-26" @default.
- W2967443126 title "Mycoplasma hyorhinis expression in patients with carcinoma of the prostate" @default.
- W2967443126 hasPublicationYear "2008" @default.
- W2967443126 type Work @default.
- W2967443126 sameAs 2967443126 @default.
- W2967443126 citedByCount "0" @default.
- W2967443126 crossrefType "journal-article" @default.
- W2967443126 hasAuthorship W2967443126A5020966829 @default.
- W2967443126 hasAuthorship W2967443126A5024594616 @default.
- W2967443126 hasAuthorship W2967443126A5040870373 @default.
- W2967443126 hasAuthorship W2967443126A5062727443 @default.
- W2967443126 hasAuthorship W2967443126A5071174564 @default.
- W2967443126 hasAuthorship W2967443126A5082611981 @default.
- W2967443126 hasConcept C121608353 @default.
- W2967443126 hasConcept C126322002 @default.
- W2967443126 hasConcept C142724271 @default.
- W2967443126 hasConcept C204232928 @default.
- W2967443126 hasConcept C2776235491 @default.
- W2967443126 hasConcept C2777546739 @default.
- W2967443126 hasConcept C2779399171 @default.
- W2967443126 hasConcept C2780192828 @default.
- W2967443126 hasConcept C71924100 @default.
- W2967443126 hasConcept C86803240 @default.
- W2967443126 hasConceptScore W2967443126C121608353 @default.
- W2967443126 hasConceptScore W2967443126C126322002 @default.
- W2967443126 hasConceptScore W2967443126C142724271 @default.
- W2967443126 hasConceptScore W2967443126C204232928 @default.
- W2967443126 hasConceptScore W2967443126C2776235491 @default.
- W2967443126 hasConceptScore W2967443126C2777546739 @default.
- W2967443126 hasConceptScore W2967443126C2779399171 @default.
- W2967443126 hasConceptScore W2967443126C2780192828 @default.
- W2967443126 hasConceptScore W2967443126C71924100 @default.
- W2967443126 hasConceptScore W2967443126C86803240 @default.
- W2967443126 hasLocation W29674431261 @default.
- W2967443126 hasOpenAccess W2967443126 @default.
- W2967443126 hasPrimaryLocation W29674431261 @default.
- W2967443126 hasRelatedWork W102221133 @default.
- W2967443126 hasRelatedWork W1892433663 @default.
- W2967443126 hasRelatedWork W2053554578 @default.
- W2967443126 hasRelatedWork W2070040127 @default.
- W2967443126 hasRelatedWork W2072177768 @default.
- W2967443126 hasRelatedWork W2103449692 @default.
- W2967443126 hasRelatedWork W2112023494 @default.
- W2967443126 hasRelatedWork W2355059910 @default.
- W2967443126 hasRelatedWork W2356539871 @default.
- W2967443126 hasRelatedWork W2365482481 @default.
- W2967443126 hasRelatedWork W2367205880 @default.
- W2967443126 hasRelatedWork W2387006846 @default.
- W2967443126 hasRelatedWork W2391303918 @default.
- W2967443126 hasRelatedWork W2397249834 @default.
- W2967443126 hasRelatedWork W2408770394 @default.
- W2967443126 hasRelatedWork W2557115668 @default.
- W2967443126 hasRelatedWork W2781531139 @default.
- W2967443126 hasRelatedWork W2979278210 @default.
- W2967443126 hasRelatedWork W3013162516 @default.
- W2967443126 hasRelatedWork W3204139218 @default.
- W2967443126 hasVolume "68" @default.
- W2967443126 isParatext "false" @default.
- W2967443126 isRetracted "false" @default.
- W2967443126 magId "2967443126" @default.
- W2967443126 workType "article" @default.