Matches in SemOpenAlex for { <https://semopenalex.org/work/W2967598413> ?p ?o ?g. }
- W2967598413 endingPage "100594" @default.
- W2967598413 startingPage "100594" @default.
- W2967598413 abstract "Thalassemia is among the most common monogenic diseases worldwide. Stem cell transplantation can be curative but is reserved for young patients, as probably gene therapy will be in the future. Adult thalassemia patients are treated with transfusion therapy and iron chelation, and improvements in the safety of transfusion protocols, use of iron chelation, monitoring of iron overload, and management of comorbidities have substantially prolonged survival, increasing the proportion of adult patients in the thalassemic population. However, older patients are more likely to develop multiple disease-related morbidities, including osteoporosis, endocrine disorders, liver disease, renal dysfunction, and cancer. Thus, the main objective of this article is to describe new challenges posed by the increasing life expectancy of patients with thalassemia, focusing on data from Italy where there is a well-documented history of thalassemia management. It is hoped that the mortality and morbidity benefits already seen in patients with thalassemia will continue to improve with ongoing advances in the quality of treatment." @default.
- W2967598413 created "2019-08-22" @default.
- W2967598413 creator A5062525225 @default.
- W2967598413 creator A5062662374 @default.
- W2967598413 creator A5069087191 @default.
- W2967598413 creator A5071250802 @default.
- W2967598413 creator A5077360808 @default.
- W2967598413 date "2019-11-01" @default.
- W2967598413 modified "2023-10-17" @default.
- W2967598413 title "Management of the aging beta-thalassemia transfusion-dependent population – The Italian experience" @default.
- W2967598413 cites W1498809087 @default.
- W2967598413 cites W1601979602 @default.
- W2967598413 cites W1604424051 @default.
- W2967598413 cites W1861356633 @default.
- W2967598413 cites W1971975530 @default.
- W2967598413 cites W1974602569 @default.
- W2967598413 cites W1974664679 @default.
- W2967598413 cites W1986972140 @default.
- W2967598413 cites W1997498169 @default.
- W2967598413 cites W1998629756 @default.
- W2967598413 cites W1999094142 @default.
- W2967598413 cites W2000076808 @default.
- W2967598413 cites W2003246990 @default.
- W2967598413 cites W2009093680 @default.
- W2967598413 cites W2012930548 @default.
- W2967598413 cites W2013316106 @default.
- W2967598413 cites W2016503316 @default.
- W2967598413 cites W2017787343 @default.
- W2967598413 cites W2021468175 @default.
- W2967598413 cites W2024054494 @default.
- W2967598413 cites W2028135932 @default.
- W2967598413 cites W2028638897 @default.
- W2967598413 cites W2032313248 @default.
- W2967598413 cites W2032889420 @default.
- W2967598413 cites W2033149201 @default.
- W2967598413 cites W2033775802 @default.
- W2967598413 cites W2034307554 @default.
- W2967598413 cites W2034754474 @default.
- W2967598413 cites W2039582673 @default.
- W2967598413 cites W2039715247 @default.
- W2967598413 cites W2046530009 @default.
- W2967598413 cites W2047584784 @default.
- W2967598413 cites W2057721700 @default.
- W2967598413 cites W2061809972 @default.
- W2967598413 cites W2064144223 @default.
- W2967598413 cites W2067697375 @default.
- W2967598413 cites W2069134767 @default.
- W2967598413 cites W2071375355 @default.
- W2967598413 cites W2072585152 @default.
- W2967598413 cites W2080142095 @default.
- W2967598413 cites W2087655054 @default.
- W2967598413 cites W2088277031 @default.
- W2967598413 cites W2099727192 @default.
- W2967598413 cites W2105511156 @default.
- W2967598413 cites W2119692077 @default.
- W2967598413 cites W2121824589 @default.
- W2967598413 cites W2123138541 @default.
- W2967598413 cites W2128195071 @default.
- W2967598413 cites W2130512886 @default.
- W2967598413 cites W2158458517 @default.
- W2967598413 cites W2160940874 @default.
- W2967598413 cites W2168463967 @default.
- W2967598413 cites W2168749033 @default.
- W2967598413 cites W2169781168 @default.
- W2967598413 cites W2238351347 @default.
- W2967598413 cites W2259787136 @default.
- W2967598413 cites W2278710601 @default.
- W2967598413 cites W2296530714 @default.
- W2967598413 cites W2324042292 @default.
- W2967598413 cites W2336289657 @default.
- W2967598413 cites W2337170605 @default.
- W2967598413 cites W2339716350 @default.
- W2967598413 cites W2419890632 @default.
- W2967598413 cites W2530520270 @default.
- W2967598413 cites W2559586911 @default.
- W2967598413 cites W2585979817 @default.
- W2967598413 cites W2594443641 @default.
- W2967598413 cites W2601947118 @default.
- W2967598413 cites W2602578275 @default.
- W2967598413 cites W2610995082 @default.
- W2967598413 cites W2625260273 @default.
- W2967598413 cites W2724824688 @default.
- W2967598413 cites W2753758710 @default.
- W2967598413 cites W2754256779 @default.
- W2967598413 cites W2765421968 @default.
- W2967598413 cites W2772146267 @default.
- W2967598413 cites W2775513502 @default.
- W2967598413 cites W2783530719 @default.
- W2967598413 cites W2791689013 @default.
- W2967598413 cites W2793167495 @default.
- W2967598413 cites W2793295368 @default.
- W2967598413 cites W2800189181 @default.
- W2967598413 cites W2801187948 @default.
- W2967598413 cites W2808877428 @default.
- W2967598413 cites W2888091897 @default.
- W2967598413 cites W2890816711 @default.
- W2967598413 cites W2892257334 @default.
- W2967598413 cites W2897606226 @default.