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• W2967661239 abstract "Abstract Background Neural stem cells (NSC) have been extensively used as a tool to investigate the mechanisms responsible for neural repair, and they have been also considered as the source for a series of promising replacement therapies in various neurodegenerative diseases. However, their use is limited by their relative rarity and anatomical localization, and also because, the methods for isolation and characterization are usually time consuming and have some technical limitations. Results In this study, we describe a resource and method for obtaining immortalized cells with NSC characteristics obtained from mouse brain embryo. Conclusions Because these cells can be maintained indefinitely in culture, they may constitute a permanent source of NSC that can be used for research studies on neural development and regeneration." @default.
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• W2967661239 date "2019-08-31" @default.
• W2967661239 modified "2023-09-25" @default.
• W2967661239 title "Immortalization of a cell line with neural stem cell characteristics derived from mouse embryo brain" @default.
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• W2967661239 doi "https://doi.org/10.1002/dvdy.103" @default.
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