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- W2967684849 abstract "(Cancer Cell 35, 504–518.e1–e7; March 18, 2019) In the originally published version of this article, an error was made in Figure S6G. When assembling and formatting the figure, we mistakenly duplicated H&E tissue images from the PTEN YF knockin treatment group (T) to the PTEN YF knockin control group (C). The revised figure now shows the correct control group tissues and has been corrected in the online article. We apologize for any confusion this error may have caused.Figure S6(Original)View Large Image Figure ViewerDownload Hi-res image Download (PPT) Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA RepairMa et al.Cancer CellFebruary 28, 2019In BriefMa et al. show that ionizing irradiation (IR) induces PTEN Y240 phosphorylation (pY240-PTEN) by FGFR2 in glioblastoma (GBM) cells. pY240-PTEN binds to chromatin and recruits RAD51 to promote DNA repair. Inhibition of Y240 phosphorylation sensitizes GBM to IR and prolongs the survival of GBM preclinical models. Full-Text PDF Open Archive" @default.
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- W2967684849 date "2019-12-01" @default.
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- W2967684849 title "Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair" @default.
- W2967684849 doi "https://doi.org/10.1016/j.ccell.2019.11.008" @default.
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