FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2967685063> ?p ?o ?g. }

• W2967685063 endingPage "120258" @default.
• W2967685063 startingPage "120258" @default.
• W2967685063 abstract "Utilizing G-quadruplex as the signal report probe, an ultrasensitive and label-free autocatalytic DNA circuit for Hg2+ detection on the basis of exonuclease III (Exo III)-assisted cascade signal amplification has been proposed. In the absence of Hg2+, the hairpin A and the DNA1 cannot hybridize due to the thymine-thymine (T-T) mismatches. Therefore, hairpin probes with the 3′-protruding terminus can be resistant to Exo III digestion, preventing the G-rich sequence to be released. In the presence of Hg2+, the combination of the DNA1 with the 3′ end-extruding hairpin A via T-Hg2+-T coordination chemistry triggers the digestion reaction of Exo III, leading to the release of the DNA1 and the sequence with domains c, d, and e. Both of the DNA1 and the sequence with domains c, d, and e can combine with other hairpin probes and activate another round of the cleavage reaction. The produced G-rich sequence can form G-quadruplex structure by binding with N-Methyl mesoporphyrin IX (NMM). The biosensor exhibits excellent selectivity and high sensitivity for Hg2+. The linear range of this biosensor is from 10 fM to 100 nM, and the linear equation can be expressed as: F610 = 1.3 × 105 Lg C + 7.40 × 104 (R2 = 0.998), in which F610 is the fluorescence intensity at 610 nm, C represents the Hg2+ concentrations, and Lg is the logarithm of 10. The detection limit is 10 fM. The biosensor is robust and can be applied to the detection of Hg2+ in water samples. By substituting the target-recognition elements, this sensing system can also be used for the detection of other metal ions." @default.
• W2967685063 created "2019-08-22" @default.
• W2967685063 creator A5010441193 @default.
• W2967685063 creator A5018386036 @default.
• W2967685063 creator A5025382217 @default.
• W2967685063 creator A5063619612 @default.
• W2967685063 creator A5089888613 @default.
• W2967685063 date "2020-01-01" @default.
• W2967685063 modified "2023-09-24" @default.
• W2967685063 title "Autocatalytic DNA circuit for Hg2+ detection with high sensitivity and selectivity based on exonuclease III and G-quadruplex DNAzyme" @default.
• W2967685063 cites W1663891098 @default.
• W2967685063 cites W1807029083 @default.
• W2967685063 cites W1973695166 @default.
• W2967685063 cites W1980451925 @default.
• W2967685063 cites W2001325691 @default.
• W2967685063 cites W2005615084 @default.
• W2967685063 cites W2007524989 @default.
• W2967685063 cites W2012020160 @default.
• W2967685063 cites W2049989960 @default.
• W2967685063 cites W2063912934 @default.
• W2967685063 cites W2068469077 @default.
• W2967685063 cites W2093468673 @default.
• W2967685063 cites W2164876360 @default.
• W2967685063 cites W2313142763 @default.
• W2967685063 cites W2327071748 @default.
• W2967685063 cites W2735032214 @default.
• W2967685063 cites W2738617810 @default.
• W2967685063 cites W2749669441 @default.
• W2967685063 cites W2773653115 @default.
• W2967685063 cites W2781977062 @default.
• W2967685063 cites W2782271669 @default.
• W2967685063 cites W2810235321 @default.
• W2967685063 cites W2897612111 @default.
• W2967685063 cites W2902938418 @default.
• W2967685063 cites W2907011108 @default.
• W2967685063 cites W2912110578 @default.
• W2967685063 cites W2913103850 @default.
• W2967685063 cites W2914504975 @default.
• W2967685063 cites W2918207729 @default.
• W2967685063 cites W2945662149 @default.
• W2967685063 cites W2945757386 @default.
• W2967685063 cites W934351548 @default.
• W2967685063 doi "https://doi.org/10.1016/j.talanta.2019.120258" @default.
• W2967685063 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31594619" @default.
• W2967685063 hasPublicationYear "2020" @default.
• W2967685063 type Work @default.
• W2967685063 sameAs 2967685063 @default.
• W2967685063 citedByCount "23" @default.
• W2967685063 countsByYear W29676850632020 @default.
• W2967685063 countsByYear W29676850632021 @default.
• W2967685063 countsByYear W29676850632022 @default.
• W2967685063 countsByYear W29676850632023 @default.
• W2967685063 crossrefType "journal-article" @default.
• W2967685063 hasAuthorship W2967685063A5010441193 @default.
• W2967685063 hasAuthorship W2967685063A5018386036 @default.
• W2967685063 hasAuthorship W2967685063A5025382217 @default.
• W2967685063 hasAuthorship W2967685063A5063619612 @default.
• W2967685063 hasAuthorship W2967685063A5089888613 @default.
• W2967685063 hasConcept C100594029 @default.
• W2967685063 hasConcept C104317684 @default.
• W2967685063 hasConcept C118792377 @default.
• W2967685063 hasConcept C119128265 @default.
• W2967685063 hasConcept C128319531 @default.
• W2967685063 hasConcept C160756335 @default.
• W2967685063 hasConcept C161790260 @default.
• W2967685063 hasConcept C178790620 @default.
• W2967685063 hasConcept C185592680 @default.
• W2967685063 hasConcept C21951064 @default.
• W2967685063 hasConcept C2756471 @default.
• W2967685063 hasConcept C2776858809 @default.
• W2967685063 hasConcept C2777501222 @default.
• W2967685063 hasConcept C2781243718 @default.
• W2967685063 hasConcept C37263863 @default.
• W2967685063 hasConcept C43617362 @default.
• W2967685063 hasConcept C547475151 @default.
• W2967685063 hasConcept C552990157 @default.
• W2967685063 hasConcept C55493867 @default.
• W2967685063 hasConcept C71240020 @default.
• W2967685063 hasConcept C84211826 @default.
• W2967685063 hasConceptScore W2967685063C100594029 @default.
• W2967685063 hasConceptScore W2967685063C104317684 @default.
• W2967685063 hasConceptScore W2967685063C118792377 @default.
• W2967685063 hasConceptScore W2967685063C119128265 @default.
• W2967685063 hasConceptScore W2967685063C128319531 @default.
• W2967685063 hasConceptScore W2967685063C160756335 @default.
• W2967685063 hasConceptScore W2967685063C161790260 @default.
• W2967685063 hasConceptScore W2967685063C178790620 @default.
• W2967685063 hasConceptScore W2967685063C185592680 @default.
• W2967685063 hasConceptScore W2967685063C21951064 @default.
• W2967685063 hasConceptScore W2967685063C2756471 @default.
• W2967685063 hasConceptScore W2967685063C2776858809 @default.
• W2967685063 hasConceptScore W2967685063C2777501222 @default.
• W2967685063 hasConceptScore W2967685063C2781243718 @default.
• W2967685063 hasConceptScore W2967685063C37263863 @default.
• W2967685063 hasConceptScore W2967685063C43617362 @default.
• W2967685063 hasConceptScore W2967685063C547475151 @default.
• W2967685063 hasConceptScore W2967685063C552990157 @default.
• W2967685063 hasConceptScore W2967685063C55493867 @default.

• next