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- W2967803412 endingPage "350" @default.
- W2967803412 startingPage "343" @default.
- W2967803412 abstract "Gene transcription is a crucial step in the sequence of molecular, synaptic, cellular, and systems mechanisms underlying learning and memory. Here, we review the experimental evidence demonstrating that alterations in the levels and functionality of the methylated DNA-binding transcriptional regulator MeCP2 are implicated in the learning and memory deficits present in mouse models of Rett syndrome and MECP2 duplication syndrome. The significant impact that MeCP2 has on gene transcription through a variety of mechanisms, combined with well-defined models of learning and memory, make MeCP2 an excellent candidate to exemplify the role of gene transcription in learning and memory. Together, these studies have strengthened the concept that precise control of activity-dependent gene transcription is a fundamental mechanism that ensures long-term adaptive behaviors necessary for the survival of individuals interacting with their congeners in an ever-changing environment." @default.
- W2967803412 created "2019-08-22" @default.
- W2967803412 creator A5026174239 @default.
- W2967803412 creator A5080296924 @default.
- W2967803412 date "2019-08-15" @default.
- W2967803412 modified "2023-09-24" @default.
- W2967803412 title "The role of MeCP2 in learning and memory" @default.
- W2967803412 cites W1211743152 @default.
- W2967803412 cites W1485187747 @default.
- W2967803412 cites W1488115555 @default.
- W2967803412 cites W1519629411 @default.
- W2967803412 cites W1559742681 @default.
- W2967803412 cites W1659536617 @default.
- W2967803412 cites W1784857457 @default.
- W2967803412 cites W1874007049 @default.
- W2967803412 cites W1964159332 @default.
- W2967803412 cites W1970207114 @default.
- W2967803412 cites W1971263143 @default.
- W2967803412 cites W1971407164 @default.
- W2967803412 cites W1974814280 @default.
- W2967803412 cites W1975714469 @default.
- W2967803412 cites W1975791071 @default.
- W2967803412 cites W1977591411 @default.
- W2967803412 cites W1977838998 @default.
- W2967803412 cites W1979526394 @default.
- W2967803412 cites W1982831423 @default.
- W2967803412 cites W1983005863 @default.
- W2967803412 cites W1987397557 @default.
- W2967803412 cites W1990645591 @default.
- W2967803412 cites W1992789817 @default.
- W2967803412 cites W1993341628 @default.
- W2967803412 cites W1995470989 @default.
- W2967803412 cites W1995502179 @default.
- W2967803412 cites W1998297242 @default.
- W2967803412 cites W1999775510 @default.
- W2967803412 cites W1999828796 @default.
- W2967803412 cites W2005729136 @default.
- W2967803412 cites W2008922065 @default.
- W2967803412 cites W2010491620 @default.
- W2967803412 cites W2016291340 @default.
- W2967803412 cites W2017816448 @default.
- W2967803412 cites W2018209199 @default.
- W2967803412 cites W2019474060 @default.
- W2967803412 cites W2021284263 @default.
- W2967803412 cites W2023796149 @default.
- W2967803412 cites W2026751327 @default.
- W2967803412 cites W2029439522 @default.
- W2967803412 cites W2029712849 @default.
- W2967803412 cites W2033063515 @default.
- W2967803412 cites W2033609439 @default.
- W2967803412 cites W2033730529 @default.
- W2967803412 cites W2035016973 @default.
- W2967803412 cites W2035090622 @default.
- W2967803412 cites W2039276157 @default.
- W2967803412 cites W2040914733 @default.
- W2967803412 cites W2041174212 @default.
- W2967803412 cites W2046022138 @default.
- W2967803412 cites W2047867886 @default.
- W2967803412 cites W2052898293 @default.
- W2967803412 cites W2057281863 @default.
- W2967803412 cites W2059045825 @default.
- W2967803412 cites W2061966117 @default.
- W2967803412 cites W2066619092 @default.
- W2967803412 cites W2074898309 @default.
- W2967803412 cites W2081854080 @default.
- W2967803412 cites W2091414779 @default.
- W2967803412 cites W2091845852 @default.
- W2967803412 cites W2093896423 @default.
- W2967803412 cites W2098277878 @default.
- W2967803412 cites W2099242898 @default.
- W2967803412 cites W2102573876 @default.
- W2967803412 cites W2102682111 @default.
- W2967803412 cites W2106360880 @default.
- W2967803412 cites W2109091674 @default.
- W2967803412 cites W2111977586 @default.
- W2967803412 cites W2113377321 @default.
- W2967803412 cites W2116602562 @default.
- W2967803412 cites W2118104607 @default.
- W2967803412 cites W2118775306 @default.
- W2967803412 cites W2122522583 @default.
- W2967803412 cites W2124105093 @default.
- W2967803412 cites W2127311839 @default.
- W2967803412 cites W2129032286 @default.
- W2967803412 cites W2149119305 @default.
- W2967803412 cites W2150661038 @default.
- W2967803412 cites W2152792694 @default.
- W2967803412 cites W2153810829 @default.
- W2967803412 cites W2155388782 @default.
- W2967803412 cites W2155543956 @default.
- W2967803412 cites W2163051245 @default.
- W2967803412 cites W2164198678 @default.
- W2967803412 cites W2165978081 @default.
- W2967803412 cites W2167375975 @default.
- W2967803412 cites W2170015414 @default.
- W2967803412 cites W2171657985 @default.
- W2967803412 cites W2172197806 @default.
- W2967803412 cites W2178727006 @default.
- W2967803412 cites W2207327903 @default.