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• W2967874046 abstract "Abstract Animals respond to sleep loss with compensatory rebound sleep, and this is thought to be critical for the maintenance of physiological homeostasis. Sleep duration varies dramatically across animal species, but it is not known whether evolutionary differences in sleep duration are associated with differences in sleep homeostasis. The Mexican cavefish, Astyanax mexicanus , has emerged as a powerful model for studying the evolution of sleep. While eyed surface populations of A. mexicanus sleep approximately eight hours each day, multiple blind cavefish populations have converged on sleep patterns that total as little as two hours each day, providing the opportunity to examine whether the evolution of sleep loss is accompanied by changes in sleep homeostasis. Here, we examine the behavioral and molecular response to sleep deprivation across four independent populations of A. mexicanus . Our behavioral analysis indicates that surface fish and all three cavefish populations display robust recovery sleep during the day following nighttime sleep deprivation, suggesting sleep homeostasis remains intact in cavefish. We profiled transcriptome-wide changes associated with sleep deprivation in surface fish and cavefish. While the total number of differentially expressed genes was not greater for the surface population, the surface population exhibited the highest number of uniquely differentially expressed genes than any other population. Strikingly, a majority of the differentially expressed genes are unique to individual cave populations, suggesting unique expression responses are exhibited across independently evolved cavefish populations. Together, these findings suggest sleep homeostasis is intact in cavefish despite a dramatic reduction in overall sleep duration." @default.
• W2967874046 created "2019-08-22" @default.
• W2967874046 creator A5009570519 @default.
• W2967874046 creator A5033001511 @default.
• W2967874046 creator A5041865755 @default.
• W2967874046 creator A5046921798 @default.
• W2967874046 creator A5068564206 @default.
• W2967874046 date "2019-08-15" @default.
• W2967874046 modified "2023-10-03" @default.
• W2967874046 title "Unique transcriptional signatures of sleep loss across independently evolved cavefish populations" @default.
• W2967874046 cites W1508670761 @default.
• W2967874046 cites W1539118047 @default.
• W2967874046 cites W1602910220 @default.
• W2967874046 cites W1731155272 @default.
• W2967874046 cites W1869105380 @default.
• W2967874046 cites W1969264427 @default.
• W2967874046 cites W1970896932 @default.
• W2967874046 cites W1973655938 @default.
• W2967874046 cites W1981105146 @default.
• W2967874046 cites W198372057 @default.
• W2967874046 cites W1992530682 @default.
• W2967874046 cites W2009101708 @default.
• W2967874046 cites W2009184553 @default.
• W2967874046 cites W2011577754 @default.
• W2967874046 cites W2013913648 @default.
• W2967874046 cites W2018107046 @default.
• W2967874046 cites W2020775714 @default.
• W2967874046 cites W2021001937 @default.
• W2967874046 cites W2022172978 @default.
• W2967874046 cites W2026345487 @default.
• W2967874046 cites W2027141772 @default.
• W2967874046 cites W2033092613 @default.
• W2967874046 cites W2045989867 @default.
• W2967874046 cites W2047578534 @default.
• W2967874046 cites W2056304509 @default.
• W2967874046 cites W2067356799 @default.
• W2967874046 cites W2079320127 @default.
• W2967874046 cites W2086185798 @default.
• W2967874046 cites W2088741298 @default.
• W2967874046 cites W2091898070 @default.
• W2967874046 cites W2093595105 @default.
• W2967874046 cites W2098139061 @default.
• W2967874046 cites W2100269353 @default.
• W2967874046 cites W2104005232 @default.
• W2967874046 cites W2106954432 @default.
• W2967874046 cites W2113136381 @default.
• W2967874046 cites W2114104545 @default.
• W2967874046 cites W2117375244 @default.
• W2967874046 cites W2128797181 @default.
• W2967874046 cites W2131271579 @default.
• W2967874046 cites W2132471961 @default.
• W2967874046 cites W2132612712 @default.
• W2967874046 cites W2134943302 @default.
• W2967874046 cites W2136823344 @default.
• W2967874046 cites W2139672495 @default.
• W2967874046 cites W2140642455 @default.
• W2967874046 cites W2168129076 @default.
• W2967874046 cites W2169456326 @default.
• W2967874046 cites W2169755065 @default.
• W2967874046 cites W2236052756 @default.
• W2967874046 cites W2252561783 @default.
• W2967874046 cites W2263310282 @default.
• W2967874046 cites W2279216355 @default.
• W2967874046 cites W2317389022 @default.
• W2967874046 cites W2395416306 @default.
• W2967874046 cites W2398266006 @default.
• W2967874046 cites W2510875395 @default.
• W2967874046 cites W2518901523 @default.
• W2967874046 cites W2520366561 @default.
• W2967874046 cites W2530172213 @default.
• W2967874046 cites W2534346109 @default.
• W2967874046 cites W2565049056 @default.
• W2967874046 cites W2574631281 @default.
• W2967874046 cites W2588419755 @default.
• W2967874046 cites W2594051410 @default.
• W2967874046 cites W2605954927 @default.
• W2967874046 cites W2623137383 @default.
• W2967874046 cites W2625934280 @default.
• W2967874046 cites W2749109001 @default.
• W2967874046 cites W2756734175 @default.
• W2967874046 cites W2785754928 @default.
• W2967874046 cites W2786031037 @default.
• W2967874046 cites W2800995660 @default.
• W2967874046 cites W2806176244 @default.
• W2967874046 cites W2807828646 @default.
• W2967874046 cites W2808214907 @default.
• W2967874046 cites W2884829456 @default.
• W2967874046 cites W2886338089 @default.
• W2967874046 cites W2888269462 @default.
• W2967874046 cites W2897314875 @default.
• W2967874046 cites W2900610658 @default.
• W2967874046 cites W2914134328 @default.
• W2967874046 cites W2920346466 @default.
• W2967874046 cites W2952378441 @default.
• W2967874046 cites W2952827404 @default.
• W2967874046 cites W4240332619 @default.
• W2967874046 doi "https://doi.org/10.1101/734673" @default.
• W2967874046 hasPublicationYear "2019" @default.
• W2967874046 type Work @default.
• W2967874046 sameAs 2967874046 @default.

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