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- W2968013346 endingPage "471" @default.
- W2968013346 startingPage "454" @default.
- W2968013346 abstract "Fine needle aspiration (FNA) is currently the standard of care for sampling pancreatic solid masses by using endoscopic ultrasound (EUS). The accuracy of the technique is reported to be high, especially if coupled with the rapid on site evaluation (ROSE), and it has a high safety profile. However, FNA presents some limitations, such as the small amount of tissue that can be collected and the inability of obtaining a core tissue with intact histological architecture, which is relevant to perform immunohistochemical analysis, molecular profiling and, therefore, targeted therapies. Moreover, the presence of the ROSE by an expert cytopathologist is very important to maximize the diagnostic yield of FNA technique; however, it is not widely available, especially in small centers. Hence, the introduction of EUS fine needle biopsy (FNB) with a new generation of needles, which show a high safety profile too and a satisfying diagnostic accuracy even in the absence of ROSE, could be the key to overcome the limitations of FNA. However, FNB has not yet shown diagnostic superiority over FNA. Considering all the technical aspects of FNA and FNB, the different types of needle currently available, comparisons in term of diagnostic yield, and the different techniques of sampling, a tailored approach should be used in order to determine the needle that is most appropriate for the different specific scenarios." @default.
- W2968013346 created "2019-08-22" @default.
- W2968013346 creator A5001856271 @default.
- W2968013346 creator A5037046840 @default.
- W2968013346 creator A5046862678 @default.
- W2968013346 date "2019-08-16" @default.
- W2968013346 modified "2023-10-03" @default.
- W2968013346 title "Endoscopic ultrasound-guided sampling of solid pancreatic masses: the fine needle aspiration or fine needle biopsy dilemma. Is the best needle yet to come?" @default.
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- W2968013346 doi "https://doi.org/10.4253/wjge.v11.i8.454" @default.
- W2968013346 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6715568" @default.