Matches in SemOpenAlex for { <https://semopenalex.org/work/W2968016123> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2968016123 abstract "Summary Retinal ganglion cells (RGCs) form the connection between the eye and the brain, with this connectivity disrupted in numerous blinding disorders. Previous studies have demonstrated the ability to derive RGCs from human pluripotent stem cells (hPSCs); however, these cells exhibited some characteristics that indicated a limited state of maturation. Among the many factors known to influence RGC development in the retina, astrocytes are known to play a significant role in their functional maturation. Thus, efforts of the current study examined the functional maturation of hPSC-derived RGCs, including the ability of astrocytes to modulate this developmental timeline. Morphological and functional properties of RGCs were found to increase over time, with astrocytes significantly accelerating the functional maturation of hPSC-derived RGCs. The results of this study clearly demonstrate the functional and morphological maturation of RGCs in vitro, including the effects of astrocytes on the maturation of hPSC-derived RGCs." @default.
- W2968016123 created "2019-08-22" @default.
- W2968016123 creator A5015094027 @default.
- W2968016123 creator A5017293822 @default.
- W2968016123 creator A5023824785 @default.
- W2968016123 creator A5042085641 @default.
- W2968016123 creator A5044333096 @default.
- W2968016123 creator A5063469751 @default.
- W2968016123 creator A5073611357 @default.
- W2968016123 creator A5077534501 @default.
- W2968016123 creator A5078097835 @default.
- W2968016123 creator A5078303221 @default.
- W2968016123 date "2019-02-12" @default.
- W2968016123 modified "2023-09-27" @default.
- W2968016123 title "Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells" @default.
- W2968016123 hasPublicationYear "2019" @default.
- W2968016123 type Work @default.
- W2968016123 sameAs 2968016123 @default.
- W2968016123 citedByCount "0" @default.
- W2968016123 crossrefType "journal-article" @default.
- W2968016123 hasAuthorship W2968016123A5015094027 @default.
- W2968016123 hasAuthorship W2968016123A5017293822 @default.
- W2968016123 hasAuthorship W2968016123A5023824785 @default.
- W2968016123 hasAuthorship W2968016123A5042085641 @default.
- W2968016123 hasAuthorship W2968016123A5044333096 @default.
- W2968016123 hasAuthorship W2968016123A5063469751 @default.
- W2968016123 hasAuthorship W2968016123A5073611357 @default.
- W2968016123 hasAuthorship W2968016123A5077534501 @default.
- W2968016123 hasAuthorship W2968016123A5078097835 @default.
- W2968016123 hasAuthorship W2968016123A5078303221 @default.
- W2968016123 hasConcept C104317684 @default.
- W2968016123 hasConcept C107459253 @default.
- W2968016123 hasConcept C145103041 @default.
- W2968016123 hasConcept C169760540 @default.
- W2968016123 hasConcept C2777093970 @default.
- W2968016123 hasConcept C28328180 @default.
- W2968016123 hasConcept C54355233 @default.
- W2968016123 hasConcept C86803240 @default.
- W2968016123 hasConcept C95444343 @default.
- W2968016123 hasConceptScore W2968016123C104317684 @default.
- W2968016123 hasConceptScore W2968016123C107459253 @default.
- W2968016123 hasConceptScore W2968016123C145103041 @default.
- W2968016123 hasConceptScore W2968016123C169760540 @default.
- W2968016123 hasConceptScore W2968016123C2777093970 @default.
- W2968016123 hasConceptScore W2968016123C28328180 @default.
- W2968016123 hasConceptScore W2968016123C54355233 @default.
- W2968016123 hasConceptScore W2968016123C86803240 @default.
- W2968016123 hasConceptScore W2968016123C95444343 @default.
- W2968016123 hasLocation W29680161231 @default.
- W2968016123 hasOpenAccess W2968016123 @default.
- W2968016123 hasPrimaryLocation W29680161231 @default.
- W2968016123 hasRelatedWork W1523528078 @default.
- W2968016123 hasRelatedWork W1526495503 @default.
- W2968016123 hasRelatedWork W1989484181 @default.
- W2968016123 hasRelatedWork W2067485884 @default.
- W2968016123 hasRelatedWork W2088886159 @default.
- W2968016123 hasRelatedWork W2309414351 @default.
- W2968016123 hasRelatedWork W2326860902 @default.
- W2968016123 hasRelatedWork W2467909618 @default.
- W2968016123 hasRelatedWork W2482409759 @default.
- W2968016123 hasRelatedWork W2527991441 @default.
- W2968016123 hasRelatedWork W2583338587 @default.
- W2968016123 hasRelatedWork W2591452691 @default.
- W2968016123 hasRelatedWork W2943675120 @default.
- W2968016123 hasRelatedWork W2949108249 @default.
- W2968016123 hasRelatedWork W2951866836 @default.
- W2968016123 hasRelatedWork W2959930022 @default.
- W2968016123 hasRelatedWork W2992169743 @default.
- W2968016123 hasRelatedWork W3013293981 @default.
- W2968016123 hasRelatedWork W3171218066 @default.
- W2968016123 hasRelatedWork W3193327507 @default.
- W2968016123 isParatext "false" @default.
- W2968016123 isRetracted "false" @default.
- W2968016123 magId "2968016123" @default.
- W2968016123 workType "article" @default.