Matches in SemOpenAlex for { <https://semopenalex.org/work/W2968020478> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2968020478 abstract "Background:Life threatening refractory asthma requiring intubation and mechanical ventilation is often associated with a high incidence of ventilator induced trauma (VILI) and has a mortality rate of around eight percent. Often these patients present with high level of arterial PaCO2 which require both a high minute ventilation and airway pressures despite lung protective ventilation and the administration of Heliox gas mixture. These ventilator requirements place this patient population at risk for excessive auto-PEEP and barotrauma. Another approach to meet gas exchange goals and to provide maximum lung protective is to place these patients on venous-venous extracorporeal oxygenation membrane (ECMO) support. The clinical rational for this management would be to protect the lung from any additional VILI and provide a stable level of ventilation and acid-base balance. Methods: During a two year time frame we placed six status asthmaticus patients with refractory gas exchange on V-V ECMO. Five of the six patients were management on V-V ECMO until the asthma exacerbation was stabilized and progressed to both ECMO and ventilator liberation. One patient expired secondary to multi-system organ failure unrelated to asthma. All patients were ventilated via pressure or volume target modes to achieve an exhaled tidal volume between 4-5cc/kg/IBW and PEEP was set via either a pressure/volume tool or via transpulmonary monitoring. ECMO parameters we set to achieve a SpO2>88% and a PH>7. 25. Results: There was no additional occurrences of additional VILI post ECMO intervention. And all patients receive pharmacological paralytics, Heliox, and continuous beta-agonist therapy for the first forty hours of mechanical ventilation and ECMO support. (Table 1) Conclusions: Based on our clinical experiences, V-V ECMO along with lung protective ventilation can provide a safe management of the status asthmaticus with refractory gas exchange." @default.
- W2968020478 created "2019-08-22" @default.
- W2968020478 creator A5040311885 @default.
- W2968020478 creator A5046428177 @default.
- W2968020478 creator A5082791570 @default.
- W2968020478 date "2018-10-01" @default.
- W2968020478 modified "2023-09-23" @default.
- W2968020478 title "The Utilization of Venous-Venous Extracorporeal Membrane Oxygenation Membrane for the Management of Status Asthmaticus" @default.
- W2968020478 hasPublicationYear "2018" @default.
- W2968020478 type Work @default.
- W2968020478 sameAs 2968020478 @default.
- W2968020478 citedByCount "0" @default.
- W2968020478 crossrefType "journal-article" @default.
- W2968020478 hasAuthorship W2968020478A5040311885 @default.
- W2968020478 hasAuthorship W2968020478A5046428177 @default.
- W2968020478 hasAuthorship W2968020478A5082791570 @default.
- W2968020478 hasConcept C126322002 @default.
- W2968020478 hasConcept C127413603 @default.
- W2968020478 hasConcept C177713679 @default.
- W2968020478 hasConcept C200457457 @default.
- W2968020478 hasConcept C27101514 @default.
- W2968020478 hasConcept C2776858399 @default.
- W2968020478 hasConcept C2777080012 @default.
- W2968020478 hasConcept C2777257755 @default.
- W2968020478 hasConcept C2777421782 @default.
- W2968020478 hasConcept C2777714996 @default.
- W2968020478 hasConcept C2780467175 @default.
- W2968020478 hasConcept C2780807750 @default.
- W2968020478 hasConcept C2908647359 @default.
- W2968020478 hasConcept C42219234 @default.
- W2968020478 hasConcept C534529494 @default.
- W2968020478 hasConcept C71924100 @default.
- W2968020478 hasConcept C78519656 @default.
- W2968020478 hasConcept C99454951 @default.
- W2968020478 hasConceptScore W2968020478C126322002 @default.
- W2968020478 hasConceptScore W2968020478C127413603 @default.
- W2968020478 hasConceptScore W2968020478C177713679 @default.
- W2968020478 hasConceptScore W2968020478C200457457 @default.
- W2968020478 hasConceptScore W2968020478C27101514 @default.
- W2968020478 hasConceptScore W2968020478C2776858399 @default.
- W2968020478 hasConceptScore W2968020478C2777080012 @default.
- W2968020478 hasConceptScore W2968020478C2777257755 @default.
- W2968020478 hasConceptScore W2968020478C2777421782 @default.
- W2968020478 hasConceptScore W2968020478C2777714996 @default.
- W2968020478 hasConceptScore W2968020478C2780467175 @default.
- W2968020478 hasConceptScore W2968020478C2780807750 @default.
- W2968020478 hasConceptScore W2968020478C2908647359 @default.
- W2968020478 hasConceptScore W2968020478C42219234 @default.
- W2968020478 hasConceptScore W2968020478C534529494 @default.
- W2968020478 hasConceptScore W2968020478C71924100 @default.
- W2968020478 hasConceptScore W2968020478C78519656 @default.
- W2968020478 hasConceptScore W2968020478C99454951 @default.
- W2968020478 hasLocation W29680204781 @default.
- W2968020478 hasOpenAccess W2968020478 @default.
- W2968020478 hasPrimaryLocation W29680204781 @default.
- W2968020478 hasRelatedWork W116078635 @default.
- W2968020478 hasRelatedWork W2024380038 @default.
- W2968020478 hasRelatedWork W2033396449 @default.
- W2968020478 hasRelatedWork W2043886336 @default.
- W2968020478 hasRelatedWork W2077338437 @default.
- W2968020478 hasRelatedWork W2291916880 @default.
- W2968020478 hasRelatedWork W2515848350 @default.
- W2968020478 hasRelatedWork W2564579194 @default.
- W2968020478 hasRelatedWork W2564785003 @default.
- W2968020478 hasRelatedWork W2593090591 @default.
- W2968020478 hasRelatedWork W2896994747 @default.
- W2968020478 hasRelatedWork W2911826624 @default.
- W2968020478 hasRelatedWork W2999892449 @default.
- W2968020478 hasRelatedWork W3015621413 @default.
- W2968020478 hasRelatedWork W3048708378 @default.
- W2968020478 hasRelatedWork W3111328927 @default.
- W2968020478 hasRelatedWork W3158407957 @default.
- W2968020478 hasRelatedWork W3196560309 @default.
- W2968020478 hasRelatedWork W75338220 @default.
- W2968020478 hasRelatedWork W948860431 @default.
- W2968020478 hasVolume "63" @default.
- W2968020478 isParatext "false" @default.
- W2968020478 isRetracted "false" @default.
- W2968020478 magId "2968020478" @default.
- W2968020478 workType "article" @default.