Matches in SemOpenAlex for { <https://semopenalex.org/work/W2968071845> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2968071845 abstract "OBJECTIVE: The objective of this study was to evaluate the gray matter (GM) volume alterations in different clinical stages of Parkinson’s disease (PD) through voxel-based morphometry (VBM). BACKGROUND: Assessment of the clinical stages of PD is usually carried out using the Hoehn and Yahr (H–Y) scale. However, there is paucity of literature on the association of GM atrophy with the progression of motor symptoms in PD. METHODS: Forty-five patients with a diagnosis of PD (H–Y I: 15, H–Y II: 15, H–Y III: 15) and 45 healthy controls (HC) were recruited. T1-weighted images were obtained through a 3-Tesla magnetic resonance imaging machine. VBM was used to compare the regional changes in the GM volume of the three groups. RESULTS: No significant differences were observed in the demographic and clinical characteristics of the groups except in the duration of symptoms (H–Y I vs. H–Y III, 2.7 ± 1.9 vs. 7.4 ± 5.2 years, P < 0.01), and Unified Parkinson’s Disease Rating Scale III ON-state score (H–Y I vs. H–Y III, 16.2 ± 8.4 vs. 24.5 ± 8.3, P < 0.02). Volume of the left parahippocampal gyrus (Brodmann area 34) was significantly different among the four groups. Post hoc analysis revealed gradual reduction in the volume of the parahippocampal gyrus from H–Y stage I (highest) to H–Y stage III (lowest). CONCLUSION: There is progressive decrease in GM volume of the parahippocampal gyrus with the advancement of stage of PD. This result suggests that the volume of parahippocampal gyrus may represent one of the neuroimaging correlates of the H–Y staging of PD." @default.
- W2968071845 created "2019-08-22" @default.
- W2968071845 creator A5003832363 @default.
- W2968071845 creator A5006776113 @default.
- W2968071845 creator A5011473220 @default.
- W2968071845 creator A5020684143 @default.
- W2968071845 creator A5071719203 @default.
- W2968071845 creator A5075826065 @default.
- W2968071845 creator A5077448329 @default.
- W2968071845 creator A5081829255 @default.
- W2968071845 creator A5084573339 @default.
- W2968071845 creator A5086079046 @default.
- W2968071845 date "2019-01-01" @default.
- W2968071845 modified "2023-09-25" @default.
- W2968071845 title "Gray matter correlates of progression of motor symptoms in patients with Parkinson’s disease" @default.
- W2968071845 doi "https://doi.org/10.4103/aomd.aomd_8_19" @default.
- W2968071845 hasPublicationYear "2019" @default.
- W2968071845 type Work @default.
- W2968071845 sameAs 2968071845 @default.
- W2968071845 citedByCount "0" @default.
- W2968071845 crossrefType "journal-article" @default.
- W2968071845 hasAuthorship W2968071845A5003832363 @default.
- W2968071845 hasAuthorship W2968071845A5006776113 @default.
- W2968071845 hasAuthorship W2968071845A5011473220 @default.
- W2968071845 hasAuthorship W2968071845A5020684143 @default.
- W2968071845 hasAuthorship W2968071845A5071719203 @default.
- W2968071845 hasAuthorship W2968071845A5075826065 @default.
- W2968071845 hasAuthorship W2968071845A5077448329 @default.
- W2968071845 hasAuthorship W2968071845A5081829255 @default.
- W2968071845 hasAuthorship W2968071845A5084573339 @default.
- W2968071845 hasAuthorship W2968071845A5086079046 @default.
- W2968071845 hasBestOaLocation W29680718451 @default.
- W2968071845 hasConcept C118552586 @default.
- W2968071845 hasConcept C126322002 @default.
- W2968071845 hasConcept C126838900 @default.
- W2968071845 hasConcept C138496976 @default.
- W2968071845 hasConcept C143409427 @default.
- W2968071845 hasConcept C15744967 @default.
- W2968071845 hasConcept C200134340 @default.
- W2968071845 hasConcept C2778048536 @default.
- W2968071845 hasConcept C2778186239 @default.
- W2968071845 hasConcept C2779134260 @default.
- W2968071845 hasConcept C2779734285 @default.
- W2968071845 hasConcept C2779991468 @default.
- W2968071845 hasConcept C2781099131 @default.
- W2968071845 hasConcept C2781172350 @default.
- W2968071845 hasConcept C2781192897 @default.
- W2968071845 hasConcept C54170458 @default.
- W2968071845 hasConcept C71924100 @default.
- W2968071845 hasConcept C83849319 @default.
- W2968071845 hasConceptScore W2968071845C118552586 @default.
- W2968071845 hasConceptScore W2968071845C126322002 @default.
- W2968071845 hasConceptScore W2968071845C126838900 @default.
- W2968071845 hasConceptScore W2968071845C138496976 @default.
- W2968071845 hasConceptScore W2968071845C143409427 @default.
- W2968071845 hasConceptScore W2968071845C15744967 @default.
- W2968071845 hasConceptScore W2968071845C200134340 @default.
- W2968071845 hasConceptScore W2968071845C2778048536 @default.
- W2968071845 hasConceptScore W2968071845C2778186239 @default.
- W2968071845 hasConceptScore W2968071845C2779134260 @default.
- W2968071845 hasConceptScore W2968071845C2779734285 @default.
- W2968071845 hasConceptScore W2968071845C2779991468 @default.
- W2968071845 hasConceptScore W2968071845C2781099131 @default.
- W2968071845 hasConceptScore W2968071845C2781172350 @default.
- W2968071845 hasConceptScore W2968071845C2781192897 @default.
- W2968071845 hasConceptScore W2968071845C54170458 @default.
- W2968071845 hasConceptScore W2968071845C71924100 @default.
- W2968071845 hasConceptScore W2968071845C83849319 @default.
- W2968071845 hasLocation W29680718451 @default.
- W2968071845 hasOpenAccess W2968071845 @default.
- W2968071845 hasPrimaryLocation W29680718451 @default.
- W2968071845 hasRelatedWork W2129285381 @default.
- W2968071845 hasRelatedWork W2186798389 @default.
- W2968071845 hasRelatedWork W2367418845 @default.
- W2968071845 hasRelatedWork W2968071845 @default.
- W2968071845 hasRelatedWork W2969314677 @default.
- W2968071845 hasRelatedWork W3010456639 @default.
- W2968071845 hasRelatedWork W3031858424 @default.
- W2968071845 hasRelatedWork W3163373794 @default.
- W2968071845 hasRelatedWork W4286716112 @default.
- W2968071845 hasRelatedWork W59825710 @default.
- W2968071845 isParatext "false" @default.
- W2968071845 isRetracted "false" @default.
- W2968071845 magId "2968071845" @default.
- W2968071845 workType "article" @default.