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- W2968135071 endingPage "566" @default.
- W2968135071 startingPage "543" @default.
- W2968135071 abstract "The atypical demyelinating syndromes are a group of conditions, characterised pathologically by demyelination, that form part of the differential diagnosis of multiple sclerosis (MS) but differ from it due to variations in clinical presentation, MRI appearance, pathology, and response to treatment. The potential for some of these syndromes to overlap with conventional MS means that diagnostic uncertainties are common and therapeutic decision-making often focuses on whether to commence MS disease-modifying therapies (DMTs) or other immunosuppression. In this chapter, the spectrum of atypical demyelinating diseases is reviewed. I discuss the difficulties in diagnosing and distinguishing between conditions such as acute disseminated encephalomyelitis (ADEM), tumefactive demyelination, Balo’s concentric sclerosis, Marburg’s multiple sclerosis, and Schilder’s diffuse myelinoclastic sclerosis and contrast these conditions with conventional MS. Advances in magnetic resonance imaging (MRI) and immunobiology may prove useful in our future understanding of these conditions." @default.
- W2968135071 created "2019-08-22" @default.
- W2968135071 creator A5009930099 @default.
- W2968135071 date "2019-01-01" @default.
- W2968135071 modified "2023-09-28" @default.
- W2968135071 title "Atypical Inflammatory Demyelinating Syndromes of the Central Nervous System" @default.
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