Matches in SemOpenAlex for { <https://semopenalex.org/work/W2968140832> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2968140832 abstract "Background Heart failure (HF) patients undergoing CRT upgrades are more symptomatic and have lower rates of reverse LV remodelling compared with de novo implants. WiSE-CRT delivers endocardial LV pacing and has many advantages over epicardial CRT which can be particularly useful in this upgrade population. Currently, WiSE-CRT is reserved for patients considered high risk for epicardial CRT such as venous occlusion, risk of pocket infection and multiple co-morbidities placing patients at an increased risk. Objectives To determine whether patients undergoing high-risk CRT upgrades with WiSE-CRT had at least comparable outcomes to epicardial CRT upgrades. Methods Consecutive patients undergoing epicardial CRT upgrades at Guy's and St Thomas’ between 2014-2018 were compared with patients undergoing high-risk CRT upgrades with a WiSE-CRT. Results 95 patients were included; 58 epicardial and 37 endocardial CRT. Baseline demographics for epicardial vs. endocardial CRT upgrades include: 71.2±12.2 vs. 67.9±11.4 years (p=0.098), 77.6±0.4 vs. 83.8±0.4% (p=0.023) male, 39.7±0.5 vs. 37.8±0.5% (p=0.859) ischaemic, QRS 176.3±27.5 vs. 182.4±29.0ms (p=0.315) and LVEF 30.2±8.2 vs. 29.7±7.9% (p=0.796). At 6 month follow-up, epicardial CRT upgrades had an 81% improvement in clinical composite score (alive, no HF hospitalisations, improvement in NYHA or global assessment) and 78% had improvement following WiSE-CRT (p=0.784). There was a trend towards a non-significant improvement in LV remodelling following WiSE-CRT compared with epicardial CRT; 73.5±0.4 vs. 66.0±0.5% (p=0.367) of patients had an absolute change in LVEF≥5% and 69.0±0.5 vs. 52.8±0.5% (p=0.185) of patients had improvement in LVESV≥15%. Conclusion Patients undergoing high-risk CRT upgrades with WiSE-CRT have comparable outcomes with those patients undergoing epicardial CRT upgrades. There is a tendency towards improved LV remodelling following WiSE-CRT, however further studies are required to determine if this reaches significance in a larger patient cohort." @default.
- W2968140832 created "2019-08-22" @default.
- W2968140832 creator A5000654487 @default.
- W2968140832 creator A5003882320 @default.
- W2968140832 creator A5019535008 @default.
- W2968140832 creator A5025035201 @default.
- W2968140832 creator A5035122361 @default.
- W2968140832 creator A5039500853 @default.
- W2968140832 creator A5043700790 @default.
- W2968140832 creator A5044198285 @default.
- W2968140832 creator A5047162197 @default.
- W2968140832 creator A5052872504 @default.
- W2968140832 creator A5057144324 @default.
- W2968140832 creator A5058395111 @default.
- W2968140832 creator A5063866014 @default.
- W2968140832 creator A5068890461 @default.
- W2968140832 creator A5069248283 @default.
- W2968140832 creator A5069742108 @default.
- W2968140832 creator A5076338368 @default.
- W2968140832 creator A5076617466 @default.
- W2968140832 creator A5078586706 @default.
- W2968140832 creator A5082209762 @default.
- W2968140832 creator A5088921468 @default.
- W2968140832 date "2019-08-01" @default.
- W2968140832 modified "2023-10-11" @default.
- W2968140832 title "Patients Undergoing High-Risk CRT Upgrades with a WiSE-CRT System Have at Trend towards Improved Left Ventricular Remodelling Compared with Epicardial CRT Upgrades" @default.
- W2968140832 doi "https://doi.org/10.1016/j.cardfail.2019.07.525" @default.
- W2968140832 hasPublicationYear "2019" @default.
- W2968140832 type Work @default.
- W2968140832 sameAs 2968140832 @default.
- W2968140832 citedByCount "0" @default.
- W2968140832 crossrefType "journal-article" @default.
- W2968140832 hasAuthorship W2968140832A5000654487 @default.
- W2968140832 hasAuthorship W2968140832A5003882320 @default.
- W2968140832 hasAuthorship W2968140832A5019535008 @default.
- W2968140832 hasAuthorship W2968140832A5025035201 @default.
- W2968140832 hasAuthorship W2968140832A5035122361 @default.
- W2968140832 hasAuthorship W2968140832A5039500853 @default.
- W2968140832 hasAuthorship W2968140832A5043700790 @default.
- W2968140832 hasAuthorship W2968140832A5044198285 @default.
- W2968140832 hasAuthorship W2968140832A5047162197 @default.
- W2968140832 hasAuthorship W2968140832A5052872504 @default.
- W2968140832 hasAuthorship W2968140832A5057144324 @default.
- W2968140832 hasAuthorship W2968140832A5058395111 @default.
- W2968140832 hasAuthorship W2968140832A5063866014 @default.
- W2968140832 hasAuthorship W2968140832A5068890461 @default.
- W2968140832 hasAuthorship W2968140832A5069248283 @default.
- W2968140832 hasAuthorship W2968140832A5069742108 @default.
- W2968140832 hasAuthorship W2968140832A5076338368 @default.
- W2968140832 hasAuthorship W2968140832A5076617466 @default.
- W2968140832 hasAuthorship W2968140832A5078586706 @default.
- W2968140832 hasAuthorship W2968140832A5082209762 @default.
- W2968140832 hasAuthorship W2968140832A5088921468 @default.
- W2968140832 hasConcept C111773187 @default.
- W2968140832 hasConcept C126322002 @default.
- W2968140832 hasConcept C164705383 @default.
- W2968140832 hasConcept C2776034619 @default.
- W2968140832 hasConcept C2778198053 @default.
- W2968140832 hasConcept C71924100 @default.
- W2968140832 hasConcept C78085059 @default.
- W2968140832 hasConceptScore W2968140832C111773187 @default.
- W2968140832 hasConceptScore W2968140832C126322002 @default.
- W2968140832 hasConceptScore W2968140832C164705383 @default.
- W2968140832 hasConceptScore W2968140832C2776034619 @default.
- W2968140832 hasConceptScore W2968140832C2778198053 @default.
- W2968140832 hasConceptScore W2968140832C71924100 @default.
- W2968140832 hasConceptScore W2968140832C78085059 @default.
- W2968140832 hasLocation W29681408321 @default.
- W2968140832 hasOpenAccess W2968140832 @default.
- W2968140832 hasPrimaryLocation W29681408321 @default.
- W2968140832 hasRelatedWork W1489596796 @default.
- W2968140832 hasRelatedWork W1500977371 @default.
- W2968140832 hasRelatedWork W1998052305 @default.
- W2968140832 hasRelatedWork W2147641919 @default.
- W2968140832 hasRelatedWork W2552233940 @default.
- W2968140832 hasRelatedWork W2609175164 @default.
- W2968140832 hasRelatedWork W2626941768 @default.
- W2968140832 hasRelatedWork W2785699536 @default.
- W2968140832 hasRelatedWork W2790842279 @default.
- W2968140832 hasRelatedWork W2891273614 @default.
- W2968140832 hasRelatedWork W2899060742 @default.
- W2968140832 hasRelatedWork W2956633466 @default.
- W2968140832 hasRelatedWork W2969026547 @default.
- W2968140832 hasRelatedWork W2969041336 @default.
- W2968140832 hasRelatedWork W3018544310 @default.
- W2968140832 hasRelatedWork W3024332396 @default.
- W2968140832 hasRelatedWork W3031348439 @default.
- W2968140832 hasRelatedWork W3112144349 @default.
- W2968140832 hasRelatedWork W3176621618 @default.
- W2968140832 hasRelatedWork W3210055190 @default.
- W2968140832 isParatext "false" @default.
- W2968140832 isRetracted "false" @default.
- W2968140832 magId "2968140832" @default.
- W2968140832 workType "article" @default.