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- W2968173664 endingPage "827" @default.
- W2968173664 startingPage "813" @default.
- W2968173664 abstract "Several high-profile examples of adverse outcomes from medications used in the perioperative setting are well known (e.g., malignant hyperthermia, prolonged apnea, respiratory depression, inadequate analgesia), leading to an increased understanding of genetic susceptibilities underlying these risks. Pharmacogenomic information is increasingly being utilized in certain areas of medicine. Despite this, routine preoperative genetic screening to inform medication risk is not yet standard practice. In this review, we assess the current readiness of pharmacogenomic information for clinical consideration for several common perioperative medications, including description of key pharmacogenes, pharmacokinetic implications and potential clinical outcomes. The goal is to highlight medications for which emerging or considerable pharmacogenomic information exists and identify areas for future potential research." @default.
- W2968173664 created "2019-08-22" @default.
- W2968173664 creator A5018398274 @default.
- W2968173664 creator A5020257221 @default.
- W2968173664 creator A5042026807 @default.
- W2968173664 creator A5066377245 @default.
- W2968173664 creator A5068268371 @default.
- W2968173664 creator A5070939740 @default.
- W2968173664 creator A5078889411 @default.
- W2968173664 creator A5084343802 @default.
- W2968173664 date "2019-07-01" @default.
- W2968173664 modified "2023-10-16" @default.
- W2968173664 title "Pharmacogenomic considerations for medications in the perioperative setting" @default.
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