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• W2968201211 abstract "Cangrelor is a relatively new antiplatelet drug that has been approved for use as an adjunct therapy to percutaneous coronary intervention (PCI) to decrease peri-procedural myocardial infarction (MI), coronary revascularization, and stent thrombosis. Cangrelor is an adenosine triphosphate analogue with a pharmacokinetic mechanism based on a reversible, dose-dependent inhibition adenosine diphosphate (ADP)-induced platelet aggregation. This drug has lately been in the spotlight as a possible bridge therapy for anti-platelet medication prior to cardiac and non-cardiac surgeries. Platelet function is usually restored within sixty minutes of cessation of therapy, thereby decreasing the risk of bleeding while providing adequate pre-procedural coverage to reduce ischemic events. This manuscript reviews the literature on cangrelor and summarizes its role as a peri-procedural bridge." @default.
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• W2968201211 date "2019-09-01" @default.
• W2968201211 modified "2023-09-29" @default.
• W2968201211 title "Intravenous cangrelor as a peri-procedural bridge with applied uses in ischemic events" @default.
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• W2968201211 doi "https://doi.org/10.21037/atm.2019.07.64" @default.
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