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- W2968227346 abstract "O-(2-[18F]Fluoroethyl)-l-tyrosine ([18F]FET) has become one of the most successful amino acid tracers for human brain tumor imaging with positron emission tomography (PET). Facile fully automated radiosynthesis and quality control (QC) of [18F]FET using our home-built automated multi-purpose 18F-radiosynthesis module are described. [18F]FET was produced in 75-80 min overall synthesis time with 20-25% radiochemical yield decay corrected to end of bombardment (EOB), based on H[18F]F. The radiochemical and enantiomeric purities were >99%, and the molar activity (Am) was 189-411 GBq/μmol at EOB. The [18F]FET dose meets all QC criteria for clinical use, and is suitable for clinical PET study of brain tumor." @default.
- W2968227346 created "2019-08-22" @default.
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- W2968227346 date "2019-12-01" @default.
- W2968227346 modified "2023-09-23" @default.
- W2968227346 title "Facile fully automated radiosynthesis and quality control of O-(2-[18F]fluoroethyl)- -tyrosine ([18F]FET) for human brain tumor imaging" @default.
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- W2968227346 doi "https://doi.org/10.1016/j.apradiso.2019.108852" @default.
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