FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2968458064> ?p ?o ?g. }

• W2968458064 endingPage "616" @default.
• W2968458064 startingPage "616" @default.
• W2968458064 abstract "The SPP1, LAP3, and LCORL are located on chromosome 6 of sheep and a domain of 36.15-38.56 Mb, which plays an essential role in tissue and embryonic growth. In this study, we cloned the complete coding sequences of SPP1 and partial coding regions of LAP3 and LCORL from Hu sheep (Gansu Province, China) and analyzed their genomic structures. The RT-qPCR showed that the three genes were expressed widely in the different tissues of Hu sheep. The SPP1 expression was significantly higher in the kidney (p < 0.01) and LAP3 expression was significantly higher in the spleen, lung, kidney, and duodenum than in the other tissues (heart, liver, rumen, muscle, fat, and ovary; p < 0.05). The LCORL was preferentially expressed in the spleen, duodenum, and lung (p < 0.05). In addition, the nucleotide substitution NM_001009224.1:c.132A>C was found in SPP1; an association analysis showed that it was associated with birth weight and yearling weight (p < 0.05), and NM_001009224.1:c.132C was the dominant allele. Two mutations XM_012179698.3:c.232C>G and XM_012179698.3:c.1154C>T were identified in LAP3. The nucleotide substitution XM_012179698.3:c.232C>G was confirmed to be associated with birth weight, 1-month weight, 3-month weight (p < 0.05), and 2-month weight (p < 0.01). The nucleotide substitution XM_012179698.3:c.1154C>T was associated with birth weight (p < 0.01), 1-month weight, and 2-month weight (p < 0.05). The LAP3 gene XM_012179698.3:c.232C>G mutation with the C allele has higher body weight than other sheep, and CC genotype individuals show higher birth weight, 1-month weight, and weaning weight than the GG genotype individuals (p < 0.05). Our results support the conclusion that the mutations on ovine SPP1 and LAP3 successfully track functional alleles that affect growth in sheep, and these genes could be used as candidate genes for improving the growth traits of sheep during breeding." @default.
• W2968458064 created "2019-08-22" @default.
• W2968458064 creator A5025707218 @default.
• W2968458064 creator A5045070373 @default.
• W2968458064 creator A5051058073 @default.
• W2968458064 creator A5075155399 @default.
• W2968458064 creator A5081469211 @default.
• W2968458064 creator A5085102872 @default.
• W2968458064 creator A5090776989 @default.
• W2968458064 date "2019-08-14" @default.
• W2968458064 modified "2023-10-14" @default.
• W2968458064 title "Molecular Characterization and Expression of SPP1, LAP3 and LCORL and Their Association with Growth Traits in Sheep" @default.
• W2968458064 cites W1534534898 @default.
• W2968458064 cites W1534906897 @default.
• W2968458064 cites W1784982965 @default.
• W2968458064 cites W1977314055 @default.
• W2968458064 cites W1999885534 @default.
• W2968458064 cites W2020352839 @default.
• W2968458064 cites W2045846497 @default.
• W2968458064 cites W2047902687 @default.
• W2968458064 cites W2052493164 @default.
• W2968458064 cites W2079306403 @default.
• W2968458064 cites W2083601322 @default.
• W2968458064 cites W2100474697 @default.
• W2968458064 cites W2102185362 @default.
• W2968458064 cites W2102334268 @default.
• W2968458064 cites W2106026012 @default.
• W2968458064 cites W2107277218 @default.
• W2968458064 cites W2117123196 @default.
• W2968458064 cites W2125105410 @default.
• W2968458064 cites W2140906391 @default.
• W2968458064 cites W2141221040 @default.
• W2968458064 cites W2147755326 @default.
• W2968458064 cites W2159400153 @default.
• W2968458064 cites W2161998322 @default.
• W2968458064 cites W2192080449 @default.
• W2968458064 cites W2416012188 @default.
• W2968458064 cites W2901121255 @default.
• W2968458064 cites W4211142228 @default.
• W2968458064 doi "https://doi.org/10.3390/genes10080616" @default.
• W2968458064 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6723280" @default.
• W2968458064 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31416156" @default.
• W2968458064 hasPublicationYear "2019" @default.
• W2968458064 type Work @default.
• W2968458064 sameAs 2968458064 @default.
• W2968458064 citedByCount "14" @default.
• W2968458064 countsByYear W29684580642020 @default.
• W2968458064 countsByYear W29684580642021 @default.
• W2968458064 countsByYear W29684580642022 @default.
• W2968458064 countsByYear W29684580642023 @default.
• W2968458064 crossrefType "journal-article" @default.
• W2968458064 hasAuthorship W2968458064A5025707218 @default.
• W2968458064 hasAuthorship W2968458064A5045070373 @default.
• W2968458064 hasAuthorship W2968458064A5051058073 @default.
• W2968458064 hasAuthorship W2968458064A5075155399 @default.
• W2968458064 hasAuthorship W2968458064A5081469211 @default.
• W2968458064 hasAuthorship W2968458064A5085102872 @default.
• W2968458064 hasAuthorship W2968458064A5090776989 @default.
• W2968458064 hasBestOaLocation W29684580641 @default.
• W2968458064 hasConcept C104317684 @default.
• W2968458064 hasConcept C126322002 @default.
• W2968458064 hasConcept C134018914 @default.
• W2968458064 hasConcept C135763542 @default.
• W2968458064 hasConcept C153209595 @default.
• W2968458064 hasConcept C153911025 @default.
• W2968458064 hasConcept C16685009 @default.
• W2968458064 hasConcept C203014093 @default.
• W2968458064 hasConcept C2776809568 @default.
• W2968458064 hasConcept C2777226302 @default.
• W2968458064 hasConcept C2780091579 @default.
• W2968458064 hasConcept C2780931953 @default.
• W2968458064 hasConcept C54355233 @default.
• W2968458064 hasConcept C71924100 @default.
• W2968458064 hasConcept C86803240 @default.
• W2968458064 hasConceptScore W2968458064C104317684 @default.
• W2968458064 hasConceptScore W2968458064C126322002 @default.
• W2968458064 hasConceptScore W2968458064C134018914 @default.
• W2968458064 hasConceptScore W2968458064C135763542 @default.
• W2968458064 hasConceptScore W2968458064C153209595 @default.
• W2968458064 hasConceptScore W2968458064C153911025 @default.
• W2968458064 hasConceptScore W2968458064C16685009 @default.
• W2968458064 hasConceptScore W2968458064C203014093 @default.
• W2968458064 hasConceptScore W2968458064C2776809568 @default.
• W2968458064 hasConceptScore W2968458064C2777226302 @default.
• W2968458064 hasConceptScore W2968458064C2780091579 @default.
• W2968458064 hasConceptScore W2968458064C2780931953 @default.
• W2968458064 hasConceptScore W2968458064C54355233 @default.
• W2968458064 hasConceptScore W2968458064C71924100 @default.
• W2968458064 hasConceptScore W2968458064C86803240 @default.
• W2968458064 hasIssue "8" @default.
• W2968458064 hasLocation W29684580641 @default.
• W2968458064 hasLocation W29684580642 @default.
• W2968458064 hasLocation W29684580643 @default.
• W2968458064 hasLocation W29684580644 @default.
• W2968458064 hasLocation W29684580645 @default.
• W2968458064 hasOpenAccess W2968458064 @default.
• W2968458064 hasPrimaryLocation W29684580641 @default.
• W2968458064 hasRelatedWork W2002592681 @default.

• next