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- W2968576864 abstract "Dendritic cells (DCs) due to their ability to present antigens are essential during the immune response to infections. The aim of the study was to evaluate the influence of bovine leukaemia virus (BLV) infection on DC properties. Cytokine profiles of myeloid, plasmacytoid and mono- cyte derived DCs from BLV infected cattle were analysed. Concentrations of IL-6, IL-10, IL-12, IFN-γ, and TNF-α in DC cultures were measured by flow cytometry. Obtained results indicated activation of pDCs population, where a significant increase in production of the IFN-γ was shown. Meanwhile, a decrease in production of IFN-γ and increase in production of IL-10 were shown in mDCs; the main population responsible for antigens presentation. This may indicate a contribu- tory role of the population during the process of persistent infection. In MoDCs population a significant elevation in secretion of proinflammatory cytokines - IL-6 and TNF-α was noted." @default.
- W2968576864 created "2019-08-22" @default.
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- W2968576864 date "2023-10-04" @default.
- W2968576864 modified "2023-10-06" @default.
- W2968576864 title "Determination of cytokine profiles in populations of dendritic cells from cattle infected with bovine leukaemia virus" @default.
- W2968576864 doi "https://doi.org/10.24425/124306" @default.
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- W2968576864 hasPublicationYear "2023" @default.
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