Matches in SemOpenAlex for { <https://semopenalex.org/work/W2968647684> ?p ?o ?g. }
- W2968647684 endingPage "161" @default.
- W2968647684 startingPage "153" @default.
- W2968647684 abstract "Abstract The aversive consequences of withdrawal from chronic alcohol abuse are risk factors for relapse drinking and alcoholism, but the underlying neuronal mechanisms are not well-understood. Accumulating evidence suggests that the lateral habenula (LHb), an epithalamic structure that connects the forebrain with the midbrain may play a crucial role. This chapter centers on the recent evidence about the effects of alcohol on the activity and synaptic transmissions of the LHb. Multidisciplinary work in rodents collectively suggests that acute and repeated alcohol exposure increases the strength of excitatory synapses and excitability of LHb neurons, which is concomitant with the affective psychiatric behaviors occurring during alcohol withdrawal. We also review evidence about the amelioration of relapse drinking and psychiatric disorders in withdrawal animals through LHb inhibition. These findings highlight a critical role for the LHb and its circuits in alcohol use disorder and related psychiatric ailments." @default.
- W2968647684 created "2019-08-22" @default.
- W2968647684 creator A5012281126 @default.
- W2968647684 creator A5017153937 @default.
- W2968647684 creator A5085894922 @default.
- W2968647684 creator A5090388270 @default.
- W2968647684 date "2019-01-01" @default.
- W2968647684 modified "2023-09-25" @default.
- W2968647684 title "The Role of the Lateral Habenula Circuitries in Alcohol Use Disorders" @default.
- W2968647684 cites W1509978278 @default.
- W2968647684 cites W1977192770 @default.
- W2968647684 cites W1990592723 @default.
- W2968647684 cites W1991236735 @default.
- W2968647684 cites W1992778334 @default.
- W2968647684 cites W1996108093 @default.
- W2968647684 cites W2000401792 @default.
- W2968647684 cites W2009680578 @default.
- W2968647684 cites W2025036158 @default.
- W2968647684 cites W2032181599 @default.
- W2968647684 cites W2045688922 @default.
- W2968647684 cites W2048342840 @default.
- W2968647684 cites W2051701625 @default.
- W2968647684 cites W2052808411 @default.
- W2968647684 cites W2056527346 @default.
- W2968647684 cites W2058575080 @default.
- W2968647684 cites W2067951508 @default.
- W2968647684 cites W2077129553 @default.
- W2968647684 cites W2078542620 @default.
- W2968647684 cites W2084200679 @default.
- W2968647684 cites W2090763917 @default.
- W2968647684 cites W2093398004 @default.
- W2968647684 cites W2140986639 @default.
- W2968647684 cites W2154579172 @default.
- W2968647684 cites W2195327708 @default.
- W2968647684 cites W2224978811 @default.
- W2968647684 cites W2323146661 @default.
- W2968647684 cites W2333514000 @default.
- W2968647684 cites W2400945916 @default.
- W2968647684 cites W2413680873 @default.
- W2968647684 cites W2473866551 @default.
- W2968647684 cites W2491859250 @default.
- W2968647684 cites W2522042922 @default.
- W2968647684 cites W2525730056 @default.
- W2968647684 cites W2529712316 @default.
- W2968647684 cites W2567343056 @default.
- W2968647684 cites W2586162504 @default.
- W2968647684 cites W2598444008 @default.
- W2968647684 cites W2604515279 @default.
- W2968647684 cites W2608005042 @default.
- W2968647684 cites W2619748449 @default.
- W2968647684 cites W2626427251 @default.
- W2968647684 cites W2627055146 @default.
- W2968647684 cites W2724120353 @default.
- W2968647684 cites W2726996696 @default.
- W2968647684 cites W2749413142 @default.
- W2968647684 cites W2750749434 @default.
- W2968647684 cites W2767888497 @default.
- W2968647684 doi "https://doi.org/10.1016/b978-0-12-813125-1.00016-7" @default.
- W2968647684 hasPublicationYear "2019" @default.
- W2968647684 type Work @default.
- W2968647684 sameAs 2968647684 @default.
- W2968647684 citedByCount "1" @default.
- W2968647684 countsByYear W29686476842022 @default.
- W2968647684 crossrefType "book-chapter" @default.
- W2968647684 hasAuthorship W2968647684A5012281126 @default.
- W2968647684 hasAuthorship W2968647684A5017153937 @default.
- W2968647684 hasAuthorship W2968647684A5085894922 @default.
- W2968647684 hasAuthorship W2968647684A5090388270 @default.
- W2968647684 hasConcept C15744967 @default.
- W2968647684 hasConcept C169760540 @default.
- W2968647684 hasConcept C2780374578 @default.
- W2968647684 hasConcept C2781066024 @default.
- W2968647684 hasConcept C529278444 @default.
- W2968647684 hasConcept C55493867 @default.
- W2968647684 hasConcept C86803240 @default.
- W2968647684 hasConceptScore W2968647684C15744967 @default.
- W2968647684 hasConceptScore W2968647684C169760540 @default.
- W2968647684 hasConceptScore W2968647684C2780374578 @default.
- W2968647684 hasConceptScore W2968647684C2781066024 @default.
- W2968647684 hasConceptScore W2968647684C529278444 @default.
- W2968647684 hasConceptScore W2968647684C55493867 @default.
- W2968647684 hasConceptScore W2968647684C86803240 @default.
- W2968647684 hasLocation W29686476841 @default.
- W2968647684 hasOpenAccess W2968647684 @default.
- W2968647684 hasPrimaryLocation W29686476841 @default.
- W2968647684 hasRelatedWork W1971289253 @default.
- W2968647684 hasRelatedWork W2056527346 @default.
- W2968647684 hasRelatedWork W2073763059 @default.
- W2968647684 hasRelatedWork W2137316421 @default.
- W2968647684 hasRelatedWork W2340467567 @default.
- W2968647684 hasRelatedWork W2800343910 @default.
- W2968647684 hasRelatedWork W2947416344 @default.
- W2968647684 hasRelatedWork W2950254639 @default.
- W2968647684 hasRelatedWork W2969334401 @default.
- W2968647684 hasRelatedWork W3006252764 @default.
- W2968647684 isParatext "false" @default.
- W2968647684 isRetracted "false" @default.
- W2968647684 magId "2968647684" @default.