Matches in SemOpenAlex for { <https://semopenalex.org/work/W2968705572> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2968705572 endingPage "78" @default.
- W2968705572 startingPage "73" @default.
- W2968705572 abstract "Aim . To present a technique for obtaining fibrinogen concentrate purified from ballast proteins, which can be used in hemostatic drug production. Materials and methods. The proposed method is based on isolating fibrinogen from a cryoprecipitate solution by its precipitation with a polyethylene glycol solution followed by virus inactivation by a solvent/detergent. Purification from viral inactivation products and ballast proteins is performed by a two-step processing of the obtained fibrinogen concentrate with glycine solution. Results. The developed laboratory method for isolating fibrinogen has been optimized in terms of main parameters and scaled in pilot production. Conclusion. The presented laboratory technique for fibrinogen extraction is characterized by a high yield of the target product, thus being suitable for the production of hemostatic drugs." @default.
- W2968705572 created "2019-08-22" @default.
- W2968705572 creator A5039789668 @default.
- W2968705572 creator A5040392752 @default.
- W2968705572 creator A5069338464 @default.
- W2968705572 creator A5077345914 @default.
- W2968705572 date "2019-08-10" @default.
- W2968705572 modified "2023-09-30" @default.
- W2968705572 title "PRODUCTION OF PURIFIED FIBRINOGEN CONCENTRATE" @default.
- W2968705572 cites W1927136087 @default.
- W2968705572 cites W1991583204 @default.
- W2968705572 cites W1993203868 @default.
- W2968705572 cites W2078132464 @default.
- W2968705572 cites W2146012199 @default.
- W2968705572 cites W2321549943 @default.
- W2968705572 doi "https://doi.org/10.35754/0234-5730-2019-64-1-73-78" @default.
- W2968705572 hasPublicationYear "2019" @default.
- W2968705572 type Work @default.
- W2968705572 sameAs 2968705572 @default.
- W2968705572 citedByCount "0" @default.
- W2968705572 crossrefType "journal-article" @default.
- W2968705572 hasAuthorship W2968705572A5039789668 @default.
- W2968705572 hasAuthorship W2968705572A5040392752 @default.
- W2968705572 hasAuthorship W2968705572A5069338464 @default.
- W2968705572 hasAuthorship W2968705572A5077345914 @default.
- W2968705572 hasBestOaLocation W29687055721 @default.
- W2968705572 hasConcept C107054158 @default.
- W2968705572 hasConcept C121332964 @default.
- W2968705572 hasConcept C153294291 @default.
- W2968705572 hasConcept C185592680 @default.
- W2968705572 hasConcept C2776964284 @default.
- W2968705572 hasConcept C2778258694 @default.
- W2968705572 hasConcept C2779036427 @default.
- W2968705572 hasConcept C43617362 @default.
- W2968705572 hasConcept C55493867 @default.
- W2968705572 hasConceptScore W2968705572C107054158 @default.
- W2968705572 hasConceptScore W2968705572C121332964 @default.
- W2968705572 hasConceptScore W2968705572C153294291 @default.
- W2968705572 hasConceptScore W2968705572C185592680 @default.
- W2968705572 hasConceptScore W2968705572C2776964284 @default.
- W2968705572 hasConceptScore W2968705572C2778258694 @default.
- W2968705572 hasConceptScore W2968705572C2779036427 @default.
- W2968705572 hasConceptScore W2968705572C43617362 @default.
- W2968705572 hasConceptScore W2968705572C55493867 @default.
- W2968705572 hasIssue "1" @default.
- W2968705572 hasLocation W29687055721 @default.
- W2968705572 hasOpenAccess W2968705572 @default.
- W2968705572 hasPrimaryLocation W29687055721 @default.
- W2968705572 hasRelatedWork W1985030818 @default.
- W2968705572 hasRelatedWork W2035521453 @default.
- W2968705572 hasRelatedWork W2093700531 @default.
- W2968705572 hasRelatedWork W2102869383 @default.
- W2968705572 hasRelatedWork W2123086946 @default.
- W2968705572 hasRelatedWork W2143521469 @default.
- W2968705572 hasRelatedWork W2408782384 @default.
- W2968705572 hasRelatedWork W2516711089 @default.
- W2968705572 hasRelatedWork W2968705572 @default.
- W2968705572 hasRelatedWork W3132482680 @default.
- W2968705572 hasVolume "64" @default.
- W2968705572 isParatext "false" @default.
- W2968705572 isRetracted "false" @default.
- W2968705572 magId "2968705572" @default.
- W2968705572 workType "article" @default.