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- W2968718863 abstract "During deep brain stimulation (DBS) surgery, we analysed somatosensory evoked potentials (SSEPs) using microelectrode recordings (MERs) in patients under general anaesthesia.We obtained MERs from 5 patients with refractory epilepsy. Off-line analysis isolated local field potentials (LFPs, 2-200 Hz) and high frequency components (HFCs, 0.5-5 kHz). Trajectories were reconstructed off-line.The ventral caudate (V.c.) nucleus was most frequently recorded from (171 mm). Very high frequency oscillations (VHFOs) were recorded up to 8 mm in length from all 4 electrodes but were most frequently recorded from the V.c. The properties of VHFOs were similar among all nuclei (frequency >1500 Hz, amplitude ∼3 µV, starting time ∼14 ms, duration 8-9 ms). Consecutive recordings did not show any synchronization or propagation, but a new kind of potential (high frequency oscillation, HFO) appeared abruptly inside the V.c. (frequency = 848 ± 66 Hz, amplitude = 5.2 ± 1.8 µV starting at 17.7 ± 0.5 ms, spanning 3.4 ± 0.3 ms).VHFOs are widely extending and cannot be ascribed to the V.c. HFOs in patients under general anaesthesia can serve as a landmark to identify the V.c. in thalamic DBS surgery.Thalamic processing involves nuclei other than the V.c, and HFO can be used to improve DBS surgery." @default.
- W2968718863 created "2019-08-22" @default.
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- W2968718863 date "2019-10-01" @default.
- W2968718863 modified "2023-09-24" @default.
- W2968718863 title "A new potential specifically marks the sensory thalamus in anaesthetised patients" @default.
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- W2968718863 doi "https://doi.org/10.1016/j.clinph.2019.07.026" @default.
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