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• W2968758539 abstract "The design of hybrid (chimeric) molecules containing two different pharmacophores connected via a spacer (linker) is a promising approach to the functionalization of natural compounds and potentially of drug molecules. These are important examples for the use of this approach with anthracycline antibiotics. The use of this methodology may help to eliminate some of the drawbacks of anthracycline drugs, e.g., high cardiotoxicity and MDR development." @default.
• W2968758539 created "2019-08-22" @default.
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• W2968758539 date "2019-10-01" @default.
• W2968758539 modified "2023-10-03" @default.
• W2968758539 title "Synthesis and antitumor activity of daunorubicin conjugates with of 3,4-methylendioxybenzaldehyde" @default.
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• W2968758539 doi "https://doi.org/10.1016/j.bmcl.2019.08.021" @default.
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