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• W2968763903 abstract "Study ObjectiveTo compare enucleation time, total operative time, and perioperative complications during laparoscopic myomectomy in patients pretreated with ulipristal acetate (UPA) compared with untreated patients.DesignProspective, observational pilot study.SettingTertiary referral center of minimally invasive gynecologic surgery, Sant'Orsola Academic Hospital, Bologna, Italy.PatientsSeventy-four of 108 patients scheduled for laparoscopic myomectomy from January to November 2017 were enrolled.InterventionsLaparoscopic myomectomy following pretreatment with UPA or no hormonal pretreatment therapy.Measurements and Main ResultsOf the 74 patients who were enrolled, 29 were pretreated with UPA (UPA group), and 45 did not receive any hormonal therapy before surgery (control group). Surgeons, blinded to patient pre-operative treatment, completed a 3-item questionnaire after each procedure to evaluate surgical difficulty. Based on surgeon response, myomas in the UPA group appeared softer and more difficult to enucleate because of less clear cleavage planes than the control group. The overall difficulty of myoma detachment from the myometrium was judged considerably higher in the UPA group. Despite this, enucleation time, total operative time, and perioperative complications were not statistically different in the 2 groups.ConclusionMyomas in patients pretreated with UPA are subjectively less easy to enucleate; however, surgical times and perioperative outcomes are not affected by pretreatment with UPA." @default.
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• W2968763903 date "2020-03-01" @default.
• W2968763903 modified "2023-10-14" @default.
• W2968763903 title "First Impressions Can Be Deceiving: Surgical Outcomes of Laparoscopic Myomectomy in Patients Pretreated with Ulipristal Acetate" @default.
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• W2968763903 doi "https://doi.org/10.1016/j.jmig.2019.04.026" @default.
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