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• W2968763927 abstract "The aim of the present study was to investigate the existence of a critical threshold beyond which peripheral fatigue would not further decrease during knee extensor (KE) exercise in older men, and the consequences of this mechanism on the force-duration relationship. Twelve old men (59 ± 2 years) randomly performed two different sessions, in which they performed 60 maximum voluntary contractions (MVC; 3s contraction, 2s relaxation). One trial was performed in the unfatigued state (CTRL) and one other following fatiguing neuromuscular electrical stimulation of the KE (FNMES). Peripheral and central fatigue were quantified via pre/post-exercise decreases in quadriceps twitch-force (Δ Ptw) and voluntary activation (ΔVA). Critical torque (CT) was determined as the mean force of the last 12 contractions while W′ was calculated as the area above CT. Compared with CTRL, pre-fatigue (Δ Ptw = −10.3 ± 6.2%) resulted in a significant (p < 0.05) reduction in W’ (−18.2 ± 1.6%) in FNMES. However, CT (∼964 N), ΔVA (∼15%) and Δ Ptw (∼25%) post-MVCs were similar between both conditions. In CTRL, W’ was correlated with Δ Ptw (r2 = 0.78). Moreover, the difference in W’ between CTRL and FNMES was correlated with the level of pre-fatigue induced in FNMES (r2 = 0.76). These findings document that peripheral fatigue is confined to an individual threshold during KE exercise in older men. Furthermore, correlative results suggest that mechanisms regulating peripheral fatigue to a critical threshold also restrict W’, and therefore play a role in exercise capacity in older men." @default.
• W2968763927 created "2019-08-22" @default.
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• W2968763927 date "2019-08-22" @default.
• W2968763927 modified "2023-10-18" @default.
• W2968763927 title "Centrally-mediated regulation of peripheral fatigue during knee extensor exercise and consequences on the force-duration relationship in older men" @default.
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• W2968763927 doi "https://doi.org/10.1080/17461391.2019.1655099" @default.
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