FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2968779105> ?p ?o ?g. }

• W2968779105 abstract "Abstract Background Repetitive transcranial magnetic stimulation (rTMS) is used to investigate normal brain function in healthy participants and as a treatment for brain disorders. Various subject factors can influence individual response to rTMS, including brain network properties. Objective/Hypothesis A previous study by our group showed that ‘virtually lesioning’ the left dorsolateral prefrontal cortex (dlPFC; important for cognitive flexibility) using inhibitory rTMS reduced performance on a set-shifting task. We aimed to determine whether this behavioural response was related to topological features of pre-TMS resting-state and task-based functional networks. Methods Inhibitory (1Hz) rTMS was applied to the left dlPFC in 16 healthy participants, and to the vertex in 17 participants as a control condition. Participants performed a set-shifting task during fMRI at baseline and directly after a single rTMS session 1-2 weeks later. Functional network topology measures were calculated from resting-state and task-based fMRI scans using graph theoretical analysis. Results The dlPFC-stimulated group, but not the vertex group, showed reduced set shifting performance after rTMS associated with lower task-based betweenness centrality of the dlPFC at baseline (p=.030) and a smaller reduction in task-based betweenness centrality after rTMS (p=.024). Reduced repeat trial accuracy after rTMS was associated with higher baseline resting state node strength of the dlPFC (p=.017). Conclusions Our results suggest that behavioural response to inhibitory rTMS to the dlPFC is dependent on baseline functional network features. Individuals with more globally integrated stimulated regions show greater resilience to inhibitory rTMS, while individuals with more locally well-connected regions show greater vulnerability. Highlights Functional brain network properties predict behavioural response to 1Hz DLPFC rTMS Globally integrated stimulated regions are resilient to effects of inhibitory rTMS Segregated, locally well-connected regions are vulnerable to inhibitory rTMS Change in performance after rTMS correlates with change in network properties" @default.
• W2968779105 created "2019-08-22" @default.
• W2968779105 creator A5006775126 @default.
• W2968779105 creator A5014542175 @default.
• W2968779105 creator A5016766601 @default.
• W2968779105 creator A5070997624 @default.
• W2968779105 creator A5090414948 @default.
• W2968779105 date "2019-08-15" @default.
• W2968779105 modified "2023-09-26" @default.
• W2968779105 title "Resting-state and task-based centrality of dorsolateral prefrontal cortex predict resilience to inhibitory repetitive transcranial magnetic stimulation" @default.
• W2968779105 cites W1687468892 @default.
• W2968779105 cites W1760829075 @default.
• W2968779105 cites W1849616893 @default.
• W2968779105 cites W1857064333 @default.
• W2968779105 cites W1966460145 @default.
• W2968779105 cites W1981244178 @default.
• W2968779105 cites W1987464027 @default.
• W2968779105 cites W1988751658 @default.
• W2968779105 cites W1990134753 @default.
• W2968779105 cites W1999174202 @default.
• W2968779105 cites W2006096283 @default.
• W2968779105 cites W2007729962 @default.
• W2968779105 cites W2019823588 @default.
• W2968779105 cites W2019930104 @default.
• W2968779105 cites W2020055733 @default.
• W2968779105 cites W2020641665 @default.
• W2968779105 cites W2023687307 @default.
• W2968779105 cites W2031713841 @default.
• W2968779105 cites W2036231449 @default.
• W2968779105 cites W2037776963 @default.
• W2968779105 cites W2042206901 @default.
• W2968779105 cites W2079418286 @default.
• W2968779105 cites W2079450984 @default.
• W2968779105 cites W2088326070 @default.
• W2968779105 cites W2088905367 @default.
• W2968779105 cites W2090668679 @default.
• W2968779105 cites W2095491050 @default.
• W2968779105 cites W2101375808 @default.
• W2968779105 cites W2120546516 @default.
• W2968779105 cites W2128552517 @default.
• W2968779105 cites W2132961058 @default.
• W2968779105 cites W2142814757 @default.
• W2968779105 cites W2153107438 @default.
• W2968779105 cites W2167822639 @default.
• W2968779105 cites W2402346616 @default.
• W2968779105 cites W2465224384 @default.
• W2968779105 cites W2611764076 @default.
• W2968779105 cites W2618978501 @default.
• W2968779105 cites W2782334844 @default.
• W2968779105 cites W2802442632 @default.
• W2968779105 cites W2885696377 @default.
• W2968779105 cites W4238079920 @default.
• W2968779105 cites W565631165 @default.
• W2968779105 cites W820930954 @default.
• W2968779105 doi "https://doi.org/10.1101/735506" @default.
• W2968779105 hasPublicationYear "2019" @default.
• W2968779105 type Work @default.
• W2968779105 sameAs 2968779105 @default.
• W2968779105 citedByCount "0" @default.
• W2968779105 crossrefType "posted-content" @default.
• W2968779105 hasAuthorship W2968779105A5006775126 @default.
• W2968779105 hasAuthorship W2968779105A5014542175 @default.
• W2968779105 hasAuthorship W2968779105A5016766601 @default.
• W2968779105 hasAuthorship W2968779105A5070997624 @default.
• W2968779105 hasAuthorship W2968779105A5090414948 @default.
• W2968779105 hasBestOaLocation W29687791051 @default.
• W2968779105 hasConcept C114614502 @default.
• W2968779105 hasConcept C117045392 @default.
• W2968779105 hasConcept C15744967 @default.
• W2968779105 hasConcept C169760540 @default.
• W2968779105 hasConcept C169900460 @default.
• W2968779105 hasConcept C24998067 @default.
• W2968779105 hasConcept C2778581513 @default.
• W2968779105 hasConcept C2779226451 @default.
• W2968779105 hasConcept C2780508717 @default.
• W2968779105 hasConcept C2781195155 @default.
• W2968779105 hasConcept C2985799443 @default.
• W2968779105 hasConcept C33923547 @default.
• W2968779105 hasConcept C53811970 @default.
• W2968779105 hasConcept C66324658 @default.
• W2968779105 hasConceptScore W2968779105C114614502 @default.
• W2968779105 hasConceptScore W2968779105C117045392 @default.
• W2968779105 hasConceptScore W2968779105C15744967 @default.
• W2968779105 hasConceptScore W2968779105C169760540 @default.
• W2968779105 hasConceptScore W2968779105C169900460 @default.
• W2968779105 hasConceptScore W2968779105C24998067 @default.
• W2968779105 hasConceptScore W2968779105C2778581513 @default.
• W2968779105 hasConceptScore W2968779105C2779226451 @default.
• W2968779105 hasConceptScore W2968779105C2780508717 @default.
• W2968779105 hasConceptScore W2968779105C2781195155 @default.
• W2968779105 hasConceptScore W2968779105C2985799443 @default.
• W2968779105 hasConceptScore W2968779105C33923547 @default.
• W2968779105 hasConceptScore W2968779105C53811970 @default.
• W2968779105 hasConceptScore W2968779105C66324658 @default.
• W2968779105 hasLocation W29687791051 @default.
• W2968779105 hasLocation W29687791052 @default.
• W2968779105 hasOpenAccess W2968779105 @default.
• W2968779105 hasPrimaryLocation W29687791051 @default.
• W2968779105 hasRelatedWork W1918898887 @default.
• W2968779105 hasRelatedWork W1958861424 @default.

• next