FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2968805268> ?p ?o ?g. }

• W2968805268 endingPage "13" @default.
• W2968805268 startingPage "8" @default.
• W2968805268 abstract "Introduction Bleeding is a major complication of anticoagulation in acute pulmonary embolism (APE) while estimating individual bleeding risk remains challenging. Elevated D-dimer levels (DD) have been shown to predict bleeding events. Objectives (1) direct comparison of the capacity of bleeding risk prediction scores (VTE-BLEED, RIETE, HAS-BLED, HEMORR2HAGES) to prognosticate in-hospital bleeding events in the acute phase of APE in a real-life population of APE patients;(2) augmentation of the discriminative capacity of fore mentioned scores with DD. Materials Post-hoc analysis of a prospective observational study. DD levels were measured using the VIDAS D-dimer Exclusion test. Receiver operating characteristic curves, areas under the curve (AUC) for bleeding prediction were calculated for scores and DD. Bleeding scores+DD were compared using an established index quantifying the reclassification of patients (net reclassification index, NRI). Results 310 APE patients were included. 35(11.3%) bleeding events occurred (hematomas, GI, urinary tract, retroperitoneal, uterine, CNS, respiratory tract): 17 major (MB) and 18 clinically-relevant non-major bleedings (CRNMB), none were fatal. All scores had satisfactory AUCs (0.754–0.767), except HAS-BLED (AUC = 0.512; 0.455–0.569). DD were higher in patients with bleeding events (29,911 ng/ml vs. 4805 ng/ml, p = .031), AUC 0.621(0.520–0.721), p = .02. DD = 5750 ng/ml was characterized by OR = 2.3(95%CI 1.05–5.0) for all bleeding events. Adding DD improved the discriminatory capacity of tested scores in the non-high risk of bleeding category, NRI 0.07–03. Conclusions Of the tested scores RIETE, HEMORR2HAGES, VTE-BLEED performed best at identifying APE patients at risk of in-hospital bleeding complications. DD levels may predict in-hospital bleeding events and may improve identifying patients classified as non-high risk who experience bleeding complications." @default.
• W2968805268 created "2019-08-22" @default.
• W2968805268 creator A5001809701 @default.
• W2968805268 creator A5006186970 @default.
• W2968805268 creator A5026821629 @default.
• W2968805268 creator A5030206037 @default.
• W2968805268 creator A5046078213 @default.
• W2968805268 creator A5049626439 @default.
• W2968805268 creator A5056212512 @default.
• W2968805268 creator A5057178326 @default.
• W2968805268 creator A5058516553 @default.
• W2968805268 creator A5063323661 @default.
• W2968805268 creator A5064068213 @default.
• W2968805268 creator A5064151300 @default.
• W2968805268 date "2019-11-01" @default.
• W2968805268 modified "2023-10-16" @default.
• W2968805268 title "D-dimer levels enhance the discriminatory capacity of bleeding risk scores for predicting in-hospital bleeding events in acute pulmonary embolism" @default.
• W2968805268 cites W176602670 @default.
• W2968805268 cites W1859270852 @default.
• W2968805268 cites W1964644585 @default.
• W2968805268 cites W1967611159 @default.
• W2968805268 cites W1974789202 @default.
• W2968805268 cites W1978745101 @default.
• W2968805268 cites W2018856451 @default.
• W2968805268 cites W2029581583 @default.
• W2968805268 cites W2030988686 @default.
• W2968805268 cites W2038821159 @default.
• W2968805268 cites W2044334576 @default.
• W2968805268 cites W2071276750 @default.
• W2968805268 cites W2092668085 @default.
• W2968805268 cites W2106421416 @default.
• W2968805268 cites W2107181407 @default.
• W2968805268 cites W2115175853 @default.
• W2968805268 cites W2119221555 @default.
• W2968805268 cites W2120203545 @default.
• W2968805268 cites W2127985968 @default.
• W2968805268 cites W2151708030 @default.
• W2968805268 cites W2162499932 @default.
• W2968805268 cites W2284688597 @default.
• W2968805268 cites W2492552840 @default.
• W2968805268 cites W2530960320 @default.
• W2968805268 cites W2791549410 @default.
• W2968805268 cites W2794269286 @default.
• W2968805268 cites W2807508646 @default.
• W2968805268 cites W2888250172 @default.
• W2968805268 cites W4361773866 @default.
• W2968805268 cites W618839329 @default.
• W2968805268 doi "https://doi.org/10.1016/j.ejim.2019.08.002" @default.
• W2968805268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31427186" @default.
• W2968805268 hasPublicationYear "2019" @default.
• W2968805268 type Work @default.
• W2968805268 sameAs 2968805268 @default.
• W2968805268 citedByCount "13" @default.
• W2968805268 countsByYear W29688052682020 @default.
• W2968805268 countsByYear W29688052682021 @default.
• W2968805268 countsByYear W29688052682022 @default.
• W2968805268 countsByYear W29688052682023 @default.
• W2968805268 crossrefType "journal-article" @default.
• W2968805268 hasAuthorship W2968805268A5001809701 @default.
• W2968805268 hasAuthorship W2968805268A5006186970 @default.
• W2968805268 hasAuthorship W2968805268A5026821629 @default.
• W2968805268 hasAuthorship W2968805268A5030206037 @default.
• W2968805268 hasAuthorship W2968805268A5046078213 @default.
• W2968805268 hasAuthorship W2968805268A5049626439 @default.
• W2968805268 hasAuthorship W2968805268A5056212512 @default.
• W2968805268 hasAuthorship W2968805268A5057178326 @default.
• W2968805268 hasAuthorship W2968805268A5058516553 @default.
• W2968805268 hasAuthorship W2968805268A5063323661 @default.
• W2968805268 hasAuthorship W2968805268A5064068213 @default.
• W2968805268 hasAuthorship W2968805268A5064151300 @default.
• W2968805268 hasConcept C126322002 @default.
• W2968805268 hasConcept C141071460 @default.
• W2968805268 hasConcept C2776259030 @default.
• W2968805268 hasConcept C2776265017 @default.
• W2968805268 hasConcept C2779161974 @default.
• W2968805268 hasConcept C2779519742 @default.
• W2968805268 hasConcept C2908647359 @default.
• W2968805268 hasConcept C3017811039 @default.
• W2968805268 hasConcept C58471807 @default.
• W2968805268 hasConcept C71924100 @default.
• W2968805268 hasConcept C76318530 @default.
• W2968805268 hasConcept C90924648 @default.
• W2968805268 hasConcept C99454951 @default.
• W2968805268 hasConceptScore W2968805268C126322002 @default.
• W2968805268 hasConceptScore W2968805268C141071460 @default.
• W2968805268 hasConceptScore W2968805268C2776259030 @default.
• W2968805268 hasConceptScore W2968805268C2776265017 @default.
• W2968805268 hasConceptScore W2968805268C2779161974 @default.
• W2968805268 hasConceptScore W2968805268C2779519742 @default.
• W2968805268 hasConceptScore W2968805268C2908647359 @default.
• W2968805268 hasConceptScore W2968805268C3017811039 @default.
• W2968805268 hasConceptScore W2968805268C58471807 @default.
• W2968805268 hasConceptScore W2968805268C71924100 @default.
• W2968805268 hasConceptScore W2968805268C76318530 @default.
• W2968805268 hasConceptScore W2968805268C90924648 @default.
• W2968805268 hasConceptScore W2968805268C99454951 @default.
• W2968805268 hasFunder F4320322511 @default.
• W2968805268 hasLocation W29688052681 @default.

• next