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- W2968932019 abstract "SuleymanDemirel Universitesi TIP FAKULTESI DERGISI: 2006 Eylul; 13(3) Obez hastalarda kisa donem (1 aylik) orlistat tedavisinin plazma lipid duzeylerine etkisi Ercan Varol, Mehmet Sahin, S Murat Aslan, Mehmet Ozaydin, Ahmet Altinbas Ozet Obez hastalarda kisa donem (1 aylik) orlistat tedavisinin plazma lipid duzeylerine etkisi Kisa donem, 1 aylik orlistat tedavisinin lipid profili uzerine etkisini arastirmak. Onuc obez hastada dusuk kalorili diyete ilave olarak gunde 3 kez 120 mg orlistat verildi. Baslangic ve 1 ay sonraki plazma lipid duzeylerine bakildi. Trigliserid (TG) seviyesi 169.9 ± 62.7 mg/dl den 156.6 ± 60.4 mg/dl'ye (p<0.05), dusuk dansiteli lipoprotein kolesterol (LDL-K) seviyesi 137.7 ± 17.5 mg/dl den 136.1 ± 17.2 mg/dl'ye (p<0.05) ve total kolesterol (TK) seviyesi 222.1 ± 47.3 mg/dl den 220.8 ± 47.6 mg/dl seviyesine dustu (p<0.05). Azalmalar istatistiksel acidan anlamli idi. Yuksek dansiteli lipoprotein kolesterol (HDL-K) seviyesindeki artis anlamli degildi (36.5 ± 2.7 mg/dl den 36.9 ± 2.4 mg/dl' ye; p=0.09). Orlistat kilo verdirici etkisinden bagimsiz olarak 1 aylik kisa donemde lipid profili uzerine olumlu etkiye sahiptir. Anahtar kelimeler: Obezite, Orlistat, Kolesterol, Trigliserid Abstract Effect of short term (1 month) orlistat treatment on plasma lipid levels in obese patients The aim of the study is to investigate the effect of a short term 1–month orlistat treatment on lipid profile in obese patients. Orlistat was administered three times 120 mg in a day in conjunction with a reduced calorie diet in 13 obese patients. Plasma lipid levels were determined at beginning and 1 month later. The triglyceride level decreased from 169.9 ± 62.7 mg/dl to 156.6 ± 60.4 mg/dl (p<0.05), low density lipoprotein cholesterol level decreased from 137.7 ± 17.5 mg/dl to 136.1 ± 17.2 mg/dl (p<0.05) and total cholesterol level decreased from 222.1 ± 47.3 mg/dl to 220.8 ± 47.6 mg/dl (p<0.05). The changes were statistically significant. The increase in high density lipoprotein cholesterol levels was not statistically significant (36.5 ± 2.7 mg/dl to 36.9 ± 2.4 mg/dl; p=0.09). Orlistat has a beneficial effect on lipid profiles in 1 month short term period in obese patients regardless of weight loss. Key words: Obesity, Orlistat, Cholesterol, Triglyceride" @default.
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- W2968932019 date "2009-04-21" @default.
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- W2968932019 title "Obez hastalarda kısa dönem (1 aylık) orlistat tedavisinin plazma lipid düzeylerine etkisi" @default.
- W2968932019 doi "https://doi.org/10.17343/sdutfd.57521" @default.
- W2968932019 hasPublicationYear "2009" @default.
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