Matches in SemOpenAlex for { <https://semopenalex.org/work/W2968999213> ?p ?o ?g. }
- W2968999213 abstract "Globally, mosquitoes are known to be competent vectors to various arboviruses that cause serious and debilitating diseases to humans and animals. Conversely, mosquitoes harbor a wide array of insect specific viruses (ISVs) that are generally neglected. Extensive characterization of these ISVs is important in understanding their persistence infection effect on host behavior and arbovirus transmission. Herein, we report first time isolation of Tanay virus (TANAV) isolate YN15_103_01 in Anopheles sinensis mosquitoes from Yunnan Province, China. Phylogenetically, the isolate's nucleotide identity had more than 14.47% variance compared to previous TANAV isolates, and it clustered into an independent branch within the genus Sandewavirus in the newly proposed taxon Negevirus. TANAV growth and high titers was attained in Aag2 cells (107 PFU/mL) but with no CPE observed up to 7 days.p.i. compared to C6/36 cells that exhibited extensive CPE at 48 h.p.i. with titers of 107 PFU/mL. Contrarywise, the viral isolate did not replicate in vertebrate cell lines. Electron microscopy analyses showed that its final maturation process takes place in the cell cytoplasm. Notably, the predicted viral proteins were verified to be corresponding to the obtained SDS-PAGE protein bands. Our findings advance forth new and vital knowledge important in understanding insect specific viruses, especially TANAV." @default.
- W2968999213 created "2019-08-22" @default.
- W2968999213 creator A5002439287 @default.
- W2968999213 creator A5024951053 @default.
- W2968999213 creator A5025664350 @default.
- W2968999213 creator A5032364522 @default.
- W2968999213 creator A5034382408 @default.
- W2968999213 creator A5045167604 @default.
- W2968999213 creator A5049216056 @default.
- W2968999213 creator A5074900997 @default.
- W2968999213 creator A5084559787 @default.
- W2968999213 date "2019-08-22" @default.
- W2968999213 modified "2023-10-12" @default.
- W2968999213 title "Characterization of a Novel Tanay Virus Isolated From Anopheles sinensis Mosquitoes in Yunnan, China" @default.
- W2968999213 cites W1253856521 @default.
- W2968999213 cites W1561863552 @default.
- W2968999213 cites W1588435884 @default.
- W2968999213 cites W1830937045 @default.
- W2968999213 cites W1920555941 @default.
- W2968999213 cites W19483775 @default.
- W2968999213 cites W1965835845 @default.
- W2968999213 cites W1967478051 @default.
- W2968999213 cites W1968947874 @default.
- W2968999213 cites W1989521478 @default.
- W2968999213 cites W1997836106 @default.
- W2968999213 cites W1998108299 @default.
- W2968999213 cites W2018375557 @default.
- W2968999213 cites W2023092952 @default.
- W2968999213 cites W2045506655 @default.
- W2968999213 cites W2050059456 @default.
- W2968999213 cites W2059986511 @default.
- W2968999213 cites W2061488183 @default.
- W2968999213 cites W2072801570 @default.
- W2968999213 cites W2082667898 @default.
- W2968999213 cites W2086888164 @default.
- W2968999213 cites W2090407970 @default.
- W2968999213 cites W2092928490 @default.
- W2968999213 cites W2095239080 @default.
- W2968999213 cites W2116009888 @default.
- W2968999213 cites W2125583308 @default.
- W2968999213 cites W2129045087 @default.
- W2968999213 cites W2133992470 @default.
- W2968999213 cites W2136919267 @default.
- W2968999213 cites W2143750933 @default.
- W2968999213 cites W2147597502 @default.
- W2968999213 cites W2152770371 @default.
- W2968999213 cites W2154936936 @default.
- W2968999213 cites W2158240087 @default.
- W2968999213 cites W2159356412 @default.
- W2968999213 cites W2162744783 @default.
- W2968999213 cites W2170618071 @default.
- W2968999213 cites W2258203861 @default.
- W2968999213 cites W2296777643 @default.
- W2968999213 cites W2403822993 @default.
- W2968999213 cites W2500723320 @default.
- W2968999213 cites W2516022550 @default.
- W2968999213 cites W2524979344 @default.
- W2968999213 cites W2546352571 @default.
- W2968999213 cites W2576744019 @default.
- W2968999213 cites W2578051997 @default.
- W2968999213 cites W2582710002 @default.
- W2968999213 cites W2586958824 @default.
- W2968999213 cites W2607369158 @default.
- W2968999213 cites W2611172242 @default.
- W2968999213 cites W2623035620 @default.
- W2968999213 cites W2748180286 @default.
- W2968999213 cites W2751276158 @default.
- W2968999213 cites W2768218258 @default.
- W2968999213 cites W2775807843 @default.
- W2968999213 cites W2788524777 @default.
- W2968999213 cites W2885995415 @default.
- W2968999213 cites W2896709872 @default.
- W2968999213 cites W2900411092 @default.
- W2968999213 cites W2900647221 @default.
- W2968999213 cites W2905849725 @default.
- W2968999213 cites W2910584227 @default.
- W2968999213 cites W2922008448 @default.
- W2968999213 cites W2922655573 @default.
- W2968999213 doi "https://doi.org/10.3389/fmicb.2019.01963" @default.
- W2968999213 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6714596" @default.
- W2968999213 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31507570" @default.
- W2968999213 hasPublicationYear "2019" @default.
- W2968999213 type Work @default.
- W2968999213 sameAs 2968999213 @default.
- W2968999213 citedByCount "11" @default.
- W2968999213 countsByYear W29689992132020 @default.
- W2968999213 countsByYear W29689992132022 @default.
- W2968999213 countsByYear W29689992132023 @default.
- W2968999213 crossrefType "journal-article" @default.
- W2968999213 hasAuthorship W2968999213A5002439287 @default.
- W2968999213 hasAuthorship W2968999213A5024951053 @default.
- W2968999213 hasAuthorship W2968999213A5025664350 @default.
- W2968999213 hasAuthorship W2968999213A5032364522 @default.
- W2968999213 hasAuthorship W2968999213A5034382408 @default.
- W2968999213 hasAuthorship W2968999213A5045167604 @default.
- W2968999213 hasAuthorship W2968999213A5049216056 @default.
- W2968999213 hasAuthorship W2968999213A5074900997 @default.
- W2968999213 hasAuthorship W2968999213A5084559787 @default.
- W2968999213 hasBestOaLocation W29689992131 @default.
- W2968999213 hasConcept C126831891 @default.