Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969001444> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2969001444 abstract "The organic extract of cultured Aspergillus terreus displayed scavenging activity against ABTS•+ and DPPH free radicals, and protective activity against glutamate-induced excitotoxicity in N18-RE-105 neuroblastoma-retina hybrid cells. Bioassay-guided fractionation of the active organic extract led to the isolation of total six butenolide derivatives, including one new metabolite, named butyroscavin (1), and five previously described metabolites, butyrolactones I (2), II (3), III (4), and VII (5), and aspernolide E (6). The planar structure of butyroscavin (1) was determined by the analysis of spectroscopic data including ESIMS (electrospray ionization mass spectrometry), and 1D and 2D NMR (nuclear magnetic resonance). The absolute configuration of butyroscavin (1) was assigned by comparison of the specific rotation with those of known compounds that share the same chiral carbon. All isolated compounds were active in the radical scavenging assay, whereas only butyrolactones I (2) and VII (5) exhibited protective activity against the glutamate-induced excitotoxicity with the EC50 of 130.1 and 91.9 μM, respectively." @default.
- W2969001444 created "2019-08-22" @default.
- W2969001444 creator A5022350933 @default.
- W2969001444 creator A5074751488 @default.
- W2969001444 date "2019-08-09" @default.
- W2969001444 modified "2023-09-30" @default.
- W2969001444 title "Butenolide derivatives from the fungus Aspergillus terreus and their radical scavenging activity and protective activity against glutamate-induced excitotoxicity" @default.
- W2969001444 cites W1881066497 @default.
- W2969001444 cites W1965903482 @default.
- W2969001444 cites W1984156662 @default.
- W2969001444 cites W2012991711 @default.
- W2969001444 cites W2034787157 @default.
- W2969001444 cites W2078909484 @default.
- W2969001444 cites W2089842365 @default.
- W2969001444 cites W2097546870 @default.
- W2969001444 cites W2114942937 @default.
- W2969001444 cites W2133040061 @default.
- W2969001444 cites W2158350898 @default.
- W2969001444 cites W2176847468 @default.
- W2969001444 cites W2312789042 @default.
- W2969001444 cites W2472117811 @default.
- W2969001444 cites W2899460232 @default.
- W2969001444 doi "https://doi.org/10.1186/s13765-019-0451-3" @default.
- W2969001444 hasPublicationYear "2019" @default.
- W2969001444 type Work @default.
- W2969001444 sameAs 2969001444 @default.
- W2969001444 citedByCount "7" @default.
- W2969001444 countsByYear W29690014442020 @default.
- W2969001444 countsByYear W29690014442022 @default.
- W2969001444 crossrefType "journal-article" @default.
- W2969001444 hasAuthorship W2969001444A5022350933 @default.
- W2969001444 hasAuthorship W2969001444A5074751488 @default.
- W2969001444 hasBestOaLocation W29690014441 @default.
- W2969001444 hasConcept C170493617 @default.
- W2969001444 hasConcept C185592680 @default.
- W2969001444 hasConcept C2776781318 @default.
- W2969001444 hasConcept C2779200925 @default.
- W2969001444 hasConcept C2781012912 @default.
- W2969001444 hasConcept C55493867 @default.
- W2969001444 hasConcept C61174792 @default.
- W2969001444 hasConcept C71240020 @default.
- W2969001444 hasConceptScore W2969001444C170493617 @default.
- W2969001444 hasConceptScore W2969001444C185592680 @default.
- W2969001444 hasConceptScore W2969001444C2776781318 @default.
- W2969001444 hasConceptScore W2969001444C2779200925 @default.
- W2969001444 hasConceptScore W2969001444C2781012912 @default.
- W2969001444 hasConceptScore W2969001444C55493867 @default.
- W2969001444 hasConceptScore W2969001444C61174792 @default.
- W2969001444 hasConceptScore W2969001444C71240020 @default.
- W2969001444 hasFunder F4320322110 @default.
- W2969001444 hasIssue "1" @default.
- W2969001444 hasLocation W29690014441 @default.
- W2969001444 hasOpenAccess W2969001444 @default.
- W2969001444 hasPrimaryLocation W29690014441 @default.
- W2969001444 hasRelatedWork W1975569432 @default.
- W2969001444 hasRelatedWork W2095102762 @default.
- W2969001444 hasRelatedWork W2158350898 @default.
- W2969001444 hasRelatedWork W2779074130 @default.
- W2969001444 hasRelatedWork W2810834944 @default.
- W2969001444 hasRelatedWork W2888007917 @default.
- W2969001444 hasRelatedWork W2890673824 @default.
- W2969001444 hasRelatedWork W2913961224 @default.
- W2969001444 hasRelatedWork W2947508329 @default.
- W2969001444 hasRelatedWork W2969001444 @default.
- W2969001444 hasVolume "62" @default.
- W2969001444 isParatext "false" @default.
- W2969001444 isRetracted "false" @default.
- W2969001444 magId "2969001444" @default.
- W2969001444 workType "article" @default.