Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969035560> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2969035560 abstract "Abstract Several reports and databases on genomic variants have associated variation in DNA sequences (≥ 1kb), or copy number variation (CNV), with susceptibility to common diseases. However, very few reports are found on hypertension and no study has been reported on CNV in prehypertensive and hypertensive young adult Malaysians. In this comparative cross-sectional study, 133 young adults were recruited, comprising of normotensive (45 subjects), prehypertensive (40 subjects) and mild hypertensive (48 subjects) subjects. DNA for CNV determination was extracted from 3 ml of blood samples collected. CNV esv27061 was analysed using optimized droplet digital polymerase chain reaction (ddPCR) method which has enhanced sensitivity and precision. Frequency distribution patterns of CNV among mild hypertensives showed highest peak copy-number-gain (number of copies more than 2) particularly in copy numbers 3 and 5. The prehypertensive subjects exhibited marked increase in copy number 5 when compared with normotensives. All the subjects in this study showed low frequency distribution pattern for copy numbers 2, 6 and 7. This discovery emphasizes the importance of frequency patterns in determining CNV status of prehypertensive and mild hypertensive subjects. Optimization method in this study showed that the detection of CNV esv27061 is possible in our sample population." @default.
- W2969035560 created "2019-08-22" @default.
- W2969035560 creator A5008572002 @default.
- W2969035560 creator A5015946136 @default.
- W2969035560 creator A5058045365 @default.
- W2969035560 creator A5071462928 @default.
- W2969035560 creator A5091640537 @default.
- W2969035560 date "2019-01-01" @default.
- W2969035560 modified "2023-09-27" @default.
- W2969035560 title "Copy number variation of CNVesv27061 analysis among young adults with high blood pressure using optimized droplet digital polymerase chain reaction (ddPCR) method" @default.
- W2969035560 cites W1973649519 @default.
- W2969035560 cites W2064543601 @default.
- W2969035560 cites W2096318664 @default.
- W2969035560 cites W2099066165 @default.
- W2969035560 cites W2143954917 @default.
- W2969035560 doi "https://doi.org/10.1016/j.matpr.2019.06.127" @default.
- W2969035560 hasPublicationYear "2019" @default.
- W2969035560 type Work @default.
- W2969035560 sameAs 2969035560 @default.
- W2969035560 citedByCount "0" @default.
- W2969035560 crossrefType "journal-article" @default.
- W2969035560 hasAuthorship W2969035560A5008572002 @default.
- W2969035560 hasAuthorship W2969035560A5015946136 @default.
- W2969035560 hasAuthorship W2969035560A5058045365 @default.
- W2969035560 hasAuthorship W2969035560A5071462928 @default.
- W2969035560 hasAuthorship W2969035560A5091640537 @default.
- W2969035560 hasBestOaLocation W29690355602 @default.
- W2969035560 hasConcept C104317684 @default.
- W2969035560 hasConcept C118190526 @default.
- W2969035560 hasConcept C120821319 @default.
- W2969035560 hasConcept C126322002 @default.
- W2969035560 hasConcept C141231307 @default.
- W2969035560 hasConcept C2908647359 @default.
- W2969035560 hasConcept C48126324 @default.
- W2969035560 hasConcept C49105822 @default.
- W2969035560 hasConcept C54355233 @default.
- W2969035560 hasConcept C71924100 @default.
- W2969035560 hasConcept C84393581 @default.
- W2969035560 hasConcept C86803240 @default.
- W2969035560 hasConcept C99454951 @default.
- W2969035560 hasConceptScore W2969035560C104317684 @default.
- W2969035560 hasConceptScore W2969035560C118190526 @default.
- W2969035560 hasConceptScore W2969035560C120821319 @default.
- W2969035560 hasConceptScore W2969035560C126322002 @default.
- W2969035560 hasConceptScore W2969035560C141231307 @default.
- W2969035560 hasConceptScore W2969035560C2908647359 @default.
- W2969035560 hasConceptScore W2969035560C48126324 @default.
- W2969035560 hasConceptScore W2969035560C49105822 @default.
- W2969035560 hasConceptScore W2969035560C54355233 @default.
- W2969035560 hasConceptScore W2969035560C71924100 @default.
- W2969035560 hasConceptScore W2969035560C84393581 @default.
- W2969035560 hasConceptScore W2969035560C86803240 @default.
- W2969035560 hasConceptScore W2969035560C99454951 @default.
- W2969035560 hasLocation W29690355601 @default.
- W2969035560 hasLocation W29690355602 @default.
- W2969035560 hasLocation W29690355603 @default.
- W2969035560 hasOpenAccess W2969035560 @default.
- W2969035560 hasPrimaryLocation W29690355601 @default.
- W2969035560 hasRelatedWork W1990724946 @default.
- W2969035560 hasRelatedWork W2055812542 @default.
- W2969035560 hasRelatedWork W2066303733 @default.
- W2969035560 hasRelatedWork W2151472315 @default.
- W2969035560 hasRelatedWork W2158004339 @default.
- W2969035560 hasRelatedWork W2166696532 @default.
- W2969035560 hasRelatedWork W2170938017 @default.
- W2969035560 hasRelatedWork W2239906618 @default.
- W2969035560 hasRelatedWork W2948383981 @default.
- W2969035560 hasRelatedWork W2969035560 @default.
- W2969035560 isParatext "false" @default.
- W2969035560 isRetracted "false" @default.
- W2969035560 magId "2969035560" @default.
- W2969035560 workType "article" @default.