Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969036062> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2969036062 endingPage "1005" @default.
- W2969036062 startingPage "998" @default.
- W2969036062 abstract "Superoxide dismutases (SODs) are one of the most important antioxidant enzymes against oxidative damage. In the present study, we cloned and expressed a novel and stable Cu, Zn-SOD from a hadal sea cucumber Psychropotes longicauda (i.e., Pl-Cu, Zn-SOD). The purified recombinant enzyme was intracellular, dimeric with the Mr. of approximately 38 kDa, with the expressed activity from 0 °C to 60 °C at an optimal temperature of 20 °C and 30 °C and maximum activity at the pH of 8.0. The Km and Vmax values of Pl-Cu, Zn-SOD were 0.041 ± 0.004 mM and 1450.275 ± 36.621 U/mg, respectively. At tested conditions, Pl-Cu, Zn-SOD was relatively stable in chemicals, such as β-ME, EDTA, Tween 20, Triton X-100, and Chaps, especially in urea and guanidine hydrochloride, which can resist protease hydrolysis and tolerate high hydrostatic pressure of 100 MPa and 2 M NaCl. All these properties make Pl-Cu, Zn-SOD a candidate in the biopharmaceutical and nutraceutical fields, and help us better understand the adaptation mechanism of hadal area." @default.
- W2969036062 created "2019-08-22" @default.
- W2969036062 creator A5024660374 @default.
- W2969036062 creator A5033747658 @default.
- W2969036062 date "2019-11-01" @default.
- W2969036062 modified "2023-10-12" @default.
- W2969036062 title "A novel, kinetically stable copper, zinc superoxide dismutase from Psychropotes longicauda" @default.
- W2969036062 cites W1911470969 @default.
- W2969036062 cites W1920721054 @default.
- W2969036062 cites W1965208511 @default.
- W2969036062 cites W1965237975 @default.
- W2969036062 cites W1979545106 @default.
- W2969036062 cites W1984375147 @default.
- W2969036062 cites W1989036315 @default.
- W2969036062 cites W2029967497 @default.
- W2969036062 cites W2033794196 @default.
- W2969036062 cites W2034555311 @default.
- W2969036062 cites W2036644638 @default.
- W2969036062 cites W2040728249 @default.
- W2969036062 cites W2043024692 @default.
- W2969036062 cites W2046371125 @default.
- W2969036062 cites W2047614338 @default.
- W2969036062 cites W2049033930 @default.
- W2969036062 cites W2051272283 @default.
- W2969036062 cites W2056151844 @default.
- W2969036062 cites W2060649546 @default.
- W2969036062 cites W2073732263 @default.
- W2969036062 cites W2074089063 @default.
- W2969036062 cites W2108345570 @default.
- W2969036062 cites W2113232199 @default.
- W2969036062 cites W2129318438 @default.
- W2969036062 cites W2143538013 @default.
- W2969036062 cites W2144852755 @default.
- W2969036062 cites W2148557032 @default.
- W2969036062 cites W2155200379 @default.
- W2969036062 cites W2159614853 @default.
- W2969036062 cites W265263939 @default.
- W2969036062 cites W2789291816 @default.
- W2969036062 cites W2804745758 @default.
- W2969036062 cites W2902421170 @default.
- W2969036062 cites W2912385772 @default.
- W2969036062 doi "https://doi.org/10.1016/j.ijbiomac.2019.08.089" @default.
- W2969036062 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31408658" @default.
- W2969036062 hasPublicationYear "2019" @default.
- W2969036062 type Work @default.
- W2969036062 sameAs 2969036062 @default.
- W2969036062 citedByCount "4" @default.
- W2969036062 countsByYear W29690360622020 @default.
- W2969036062 countsByYear W29690360622021 @default.
- W2969036062 countsByYear W29690360622022 @default.
- W2969036062 countsByYear W29690360622023 @default.
- W2969036062 crossrefType "journal-article" @default.
- W2969036062 hasAuthorship W2969036062A5024660374 @default.
- W2969036062 hasAuthorship W2969036062A5033747658 @default.
- W2969036062 hasConcept C121332964 @default.
- W2969036062 hasConcept C178790620 @default.
- W2969036062 hasConcept C181199279 @default.
- W2969036062 hasConcept C185592680 @default.
- W2969036062 hasConcept C2775838275 @default.
- W2969036062 hasConcept C2778004101 @default.
- W2969036062 hasConcept C2910081258 @default.
- W2969036062 hasConcept C535196362 @default.
- W2969036062 hasConcept C55493867 @default.
- W2969036062 hasConcept C86803240 @default.
- W2969036062 hasConcept C97355855 @default.
- W2969036062 hasConceptScore W2969036062C121332964 @default.
- W2969036062 hasConceptScore W2969036062C178790620 @default.
- W2969036062 hasConceptScore W2969036062C181199279 @default.
- W2969036062 hasConceptScore W2969036062C185592680 @default.
- W2969036062 hasConceptScore W2969036062C2775838275 @default.
- W2969036062 hasConceptScore W2969036062C2778004101 @default.
- W2969036062 hasConceptScore W2969036062C2910081258 @default.
- W2969036062 hasConceptScore W2969036062C535196362 @default.
- W2969036062 hasConceptScore W2969036062C55493867 @default.
- W2969036062 hasConceptScore W2969036062C86803240 @default.
- W2969036062 hasConceptScore W2969036062C97355855 @default.
- W2969036062 hasFunder F4320335777 @default.
- W2969036062 hasLocation W29690360621 @default.
- W2969036062 hasLocation W29690360622 @default.
- W2969036062 hasOpenAccess W2969036062 @default.
- W2969036062 hasPrimaryLocation W29690360621 @default.
- W2969036062 hasRelatedWork W1490802485 @default.
- W2969036062 hasRelatedWork W1608242839 @default.
- W2969036062 hasRelatedWork W1797037923 @default.
- W2969036062 hasRelatedWork W2037078933 @default.
- W2969036062 hasRelatedWork W2267482523 @default.
- W2969036062 hasRelatedWork W2326504209 @default.
- W2969036062 hasRelatedWork W2360203209 @default.
- W2969036062 hasRelatedWork W2372082568 @default.
- W2969036062 hasRelatedWork W2467718070 @default.
- W2969036062 hasRelatedWork W984575549 @default.
- W2969036062 hasVolume "140" @default.
- W2969036062 isParatext "false" @default.
- W2969036062 isRetracted "false" @default.
- W2969036062 magId "2969036062" @default.
- W2969036062 workType "article" @default.